DUXA (Homo sapiens)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSG00000258873 T209954_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This gene is a member of the DUXA homeobox gene family. Evidence of mRNA expression has not yet been found for this gene. Multiple, related processed pseudogenes have been found which are thought to reflect expression of this gene in the germ line or embryonic cells. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
DUXA
M01247_2.00		 Homo sapiens
NTGATTRNN
NNYAATCAN		 PBM
Lambert et al.(2019)
pTH11226		 (Direct) (Direct)
DUXA
M03244_2.00		 Homo sapiens
NHRAYBYAATCAN
NTGATTRVRTYDN		 SELEX
Jolma et al.(2013)
DUXA_1		 (Direct) (Direct)
DUXA
M05402_2.00		 Homo sapiens
TRAYBYAATCA
TGATTRVRTYA		 SELEX
Yin et al.(2017)
DUXA_eDBD_HT-SELEX		 (Direct) (Direct)
DUXA
M05403_2.00		 Homo sapiens
YRAYBYAATCA
TGATTRVRTYR		 SELEX
Yin et al.(2017)
DUXA_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
DUXA
M10756_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$DUXA_02		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.599 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M01247_2.00 Homeodomain 16 70
M01247_2.00 Homeodomain 102 156

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000452398 Homeodomain 16 70
ENSP00000452398 Homeodomain 102 156

Links

Other Homeodomain family TFs
Other Homo sapiens TFs

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30 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action