Obox6 (Mus musculus)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSMUSG00000041583 T212511_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is expressed in bladder; early conceptus; gonad; and thymus. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Obox6
M00490_2.00		 Mus musculus
NTAATCYNN
NNRGATTAN		 PBM
Berger et al.(2008)
Obox6_3440		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Obox3
M00523_2.00 		Mus musculus
NWWATMN
NKATWWN		 PBM
Berger et al.(2008)
Obox3_3439 		0.690 0.561
Obox5
M00527_2.00 		Mus musculus
NTWATHNN
NNDATWAN		 PBM
Berger et al.(2008)
Obox5_2284 		0.689 0.614
Obox5
M00528_2.00 		Mus musculus
NWDATHNN
NNDATHWN		 PBM
Berger et al.(2008)
Obox5_3963 		0.689 0.614
Obox1
M00515_2.00 		Mus musculus
NTAATCYNNN
NNNRGATTAN		 PBM
Berger et al.(2008)
Obox1_3970 		0.689 0.579
NEMVEDRAFT_v1g113057
M02144_2.00 		Nematostella vectensis
NYTAATCCBN
NVGGATTARN		 PBM
Weirauch et al.(2014)
pTH6135 		0.659 0.421
Q8VHG7_MOUSE
M00529_2.00 		Mus musculus
WTAATCCH
DGGATTAW		 PBM
Berger et al.(2008)
Obox2_3438 		0.654 0.544
CRX
M00270_2.00 		Homo sapiens
NWDAKNN
NNMTHWN		 PBM
Barrera et al.(2016)
CRX_E80A 		0.636 0.368
ceh-53
M00679_2.00 		Caenorhabditis elegans
HTAATCYN
NRGATTAD		 PBM
Narasimhan et al.(2015)
pTH10699 		0.623 0.404
Dmbx1
M00441_2.00 		Mus musculus
NTAATCYNN
NNRGATTAN		 PBM
Berger et al.(2008)
Dmbx1_2277 		0.620 0.386
DMBX1
M03236_2.00 		Homo sapiens
NHTAATCCBN
NVGGATTADN		 SELEX
Jolma et al.(2013)
DMBX1_1 		0.620 0.386
DMBX1
M05383_2.00 		Homo sapiens
NTAATCSN
NSGATTAN		 SELEX
Yin et al.(2017)
DMBX1_eDBD_HT-SELEX 		0.620 0.386
DMBX1
M05384_2.00 		Homo sapiens
HTAATCCN
NGGATTAD		 SELEX
Yin et al.(2017)
DMBX1_eDBD_Methyl-HT-SELEX 		0.620 0.386
HBX4_ECHGR
M02195_2.00 		Echinococcus granulosus
NHTAATCYNN
NNRGATTADN		 PBM
Weirauch et al.(2014)
pTH6301 		0.618 0.404
ceh-36
M00673_2.00 		Caenorhabditis elegans
NWAATCYN
NRGATTWN		 PBM
Narasimhan et al.(2015)
pTH10730 		0.616 0.368
Otx1
M00396_2.00 		Mus musculus
NTAAKCYN
NRGMTTAN		 PBM
Berger et al.(2008)
Otx1_2325 		0.616 0.368
Otx2
M00418_2.00 		Mus musculus
NTAAKMBN
NVKMTTAN		 PBM
Berger et al.(2008)
Otx2_3441 		0.616 0.368
OTX1
M03116_2.00 		Homo sapiens
NNTAAKCGGATTANN
NNTAATCCGMTTANN		 SELEX
Jolma et al.(2013)
OTX1_1 		0.616 0.368
OTX1
M03117_2.00 		Homo sapiens
NTAATCSB
VSGATTAN		 SELEX
Jolma et al.(2013)
OTX1_2 		0.616 0.368
OTX2
M03197_2.00 		Homo sapiens
NHTAAKCGGATTANN
NNTAATCCGMTTADN		 SELEX
Jolma et al.(2013)
OTX2_1 		0.616 0.368
OTX2
M03198_2.00 		Homo sapiens
HTAATCCB
VGGATTAD		 SELEX
Jolma et al.(2013)
OTX2_2 		0.616 0.368
Otx1
M03249_2.00 		Mus musculus
NNTAAKCGGATTANN
NNTAATCCGMTTANN		 SELEX
Jolma et al.(2013)
Otx1_1 		0.616 0.368
Otx1
M03250_2.00 		Mus musculus
NTAATCCN
NGGATTAN		 SELEX
Jolma et al.(2013)
Otx1_2 		0.616 0.368
oc
M03808_2.00 		Drosophila melanogaster
HTAATCCB
VGGATTAD		 SELEX
Nitta et al.(2015)
oc_1 		0.616 0.368
OTX1
M05022_2.00 		Homo sapiens
NTAATCCN
NGGATTAN		 SELEX
Yin et al.(2017)
OTX1_eDBD_HT-SELEX 		0.616 0.368
OTX1
M05024_2.00 		Homo sapiens
NTAATCCNNN
NNNGGATTAN		 SELEX
Yin et al.(2017)
OTX1_FL_HT-SELEX 		0.616 0.368
OTX2
M05251_2.00 		Homo sapiens
NTAATCCN
NGGATTAN		 SELEX
Yin et al.(2017)
OTX2_FL_HT-SELEX 		0.616 0.368
oc
M06502_2.00 		Drosophila melanogaster
TAATCC
GGATTA		 B1H
Mathelier et al.(2014)
MA0234.1 		0.616 0.368
oc
M06282_2.00 		Drosophila melanogaster
WTAATCC
GGATTAW		 B1H
Zhu et al.(2011)
Oc_Cell_FBgn0004102 		0.616 0.368
oc
M06283_2.00 		Drosophila melanogaster
NTAATCCB
VGGATTAN		 B1H
Zhu et al.(2011)
Oc_SOLEXA_FBgn0004102 		0.616 0.368
OTX2
M09153_2.00 		Homo sapiens
BYTAATCCYYN
NRRGGATTARV		 Misc
Kulakovskiy et al.(2013)
OTX2_HUMAN.H11MO.0.A 		0.616 0.368
Otx2
M09183_2.00 		Mus musculus
HTAATCCYNYNN
NNRNRGGATTAD		 Misc
Kulakovskiy et al.(2013)
OTX2_MOUSE.H11MO.0.A 		0.616 0.368
Otx2
M09569_2.00 		Mus musculus
NHTAATCCHB
VDGGATTADN		 Misc
Heinz et al.(2010)
EpiLC-Otx2_GSE56098 		0.616 0.368
oc
M09681_2.00 		Drosophila melanogaster
HTAATCCN
NGGATTAD		 Misc
Kulakovskiy et al.(2009)
oc 		0.616 0.368
OTX1
M10673_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$OTX1_Q5 		0.616 0.368
OTX2
M10727_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$OTX2_Q3_01 		0.616 0.368
OTX2
M10728_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$OTX2_Q3 		0.616 0.368
OTX1
M05023_2.00 		Homo sapiens
NTAATCCN
NGGATTAN		 SELEX
Yin et al.(2017)
OTX1_eDBD_Methyl-HT-SELEX 		0.616 0.368
OTX1
M05025_2.00 		Homo sapiens
HTAATCCNHN
NDNGGATTAD		 SELEX
Yin et al.(2017)
OTX1_FL_Methyl-HT-SELEX 		0.616 0.368
OTX2
M05252_2.00 		Homo sapiens
NTAATCCN
NGGATTAN		 SELEX
Yin et al.(2017)
OTX2_FL_Methyl-HT-SELEX 		0.616 0.368
CRX
M00274_2.00 		Homo sapiens
NMTAATCCSN
NSGGATTAKN		 PBM
Barrera et al.(2016)
CRX_REF 		0.616 0.351
Crx
M00489_2.00 		Mus musculus
NWAAKMBN
NVKMTTWN		 PBM
Berger et al.(2008)
Crx_3485 		0.616 0.351
CRX
M04949_2.00 		Homo sapiens
NTAATCCN
NGGATTAN		 SELEX
Yin et al.(2017)
CRX_FL_HT-SELEX 		0.616 0.351
Crx
M08139_2.00 		Mus musculus
YTAATCCYCYY
RRGRGGATTAR		 ChIP-seq
Mathelier et al.(2014)
MA0467.1 		0.616 0.351
CRX
M09132_2.00 		Homo sapiens
BYTAATCCBHYYN
NRRDVGGATTARV		 Misc
Kulakovskiy et al.(2013)
CRX_HUMAN.H11MO.0.B 		0.616 0.351
Crx
M09208_2.00 		Mus musculus
BYTAATCCBHYYN
NRRDVGGATTARV		 Misc
Kulakovskiy et al.(2013)
CRX_MOUSE.H11MO.0.A 		0.616 0.351
Crx
M09577_2.00 		Mus musculus
NYTAATCC
GGATTARN		 Misc
Heinz et al.(2010)
Retina-Crx_GSE20012 		0.616 0.351
CRX
M10647_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CRX_Q4_01 		0.616 0.351
CRX
M10648_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CRX_Q4_02 		0.616 0.351
CRX
M00271_2.00 		Homo sapiens
NHDAKNN
NNMTHDN		 PBM
Barrera et al.(2016)
CRX_R41Q 		0.616 0.351
CRX
M00272_2.00 		Homo sapiens
NNHNATNN
NNATNDNN		 PBM
Barrera et al.(2016)
CRX_R41W 		0.616 0.351
CRX
M00273_2.00 		Homo sapiens
NNYTAATCCVN
NBGGATTARNN		 PBM
Barrera et al.(2016)
CRX_R90W 		0.616 0.351
CRX
M00275_2.00 		Homo sapiens
NMTAATCCSN
NSGGATTAKN		 PBM
Barrera et al.(2016)
CRX_V66I 		0.616 0.351
CRX
M04950_2.00 		Homo sapiens
HTAATCCN
NGGATTAD		 SELEX
Yin et al.(2017)
CRX_FL_Methyl-HT-SELEX 		0.616 0.351
ceh-37
M00674_2.00 		Caenorhabditis elegans
HTAATCYN
NRGATTAD		 PBM
Narasimhan et al.(2015)
pTH10716 		0.611 0.351
Gsc
M00411_2.00 		Mus musculus
NNTAATYBN
NVRATTANN		 PBM
Berger et al.(2008)
Gsc_2327 		0.611 0.386
GSC
M03146_2.00 		Homo sapiens
NHTAATCCNH
DNGGATTADN		 SELEX
Jolma et al.(2013)
GSC_1 		0.611 0.386
GSC
M05134_2.00 		Homo sapiens
NTAATCCB
VGGATTAN		 SELEX
Yin et al.(2017)
GSC_eDBD_HT-SELEX 		0.611 0.386
GSC
M05136_2.00 		Homo sapiens
HTAATCCN
NGGATTAD		 SELEX
Yin et al.(2017)
GSC_FL_HT-SELEX 		0.611 0.386
gsc
M09584_2.00 		Xenopus tropicalis
NTAATCYN
NRGATTAN		 Misc
Heinz et al.(2010)
FrogEmbryos-GSC_DRA000576 		0.611 0.386
GSC
M05135_2.00 		Homo sapiens
HTAATCCB
VGGATTAD		 SELEX
Yin et al.(2017)
GSC_eDBD_Methyl-HT-SELEX 		0.611 0.386
GSC
M05137_2.00 		Homo sapiens
HTAATCCN
NGGATTAD		 SELEX
Yin et al.(2017)
GSC_FL_Methyl-HT-SELEX 		0.611 0.386
For this family, TFs with SR scores > 0.599 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00490_2.00 Homeodomain 17 73

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000104153 Homeodomain 146 202

Links

Other Homeodomain family TFs
Other Mus musculus TFs

Invalid Input OrderBy

661 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action