Duxbl1 (Mus musculus)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSMUSG00000048502 T212526_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within regulation of T cell differentiation. Located in nucleus. Is expressed in several structures, including brain; early conceptus; and genitourinary system. Orthologous to several human genes including DUX4L1 (double homeobox 4 like 1 (pseudogene)); DUX4L2 (double homeobox 4 like 2 (pseudogene)); and DUX4L4 (double homeobox 4 like 4 (pseudogene)). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Duxbl1
M00502_2.00		 Mus musculus
NWGATKRNNN
NNNYMATCWN		 PBM
Berger et al.(2008)
Duxl_1286		 (Direct) (Direct)
Duxbl1
M02099_2.00		 Mus musculus
NTGATTRNN
NNYAATCAN		 PBM
Weirauch et al.(2014)
pTH6453		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.599 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00502_2.00 Homeodomain 14 70
M00502_2.00 Homeodomain 94 148
M02099_2.00 Homeodomain 1 55

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000056056 Homeodomain 15 71
ENSMUSP00000056056 Homeodomain 95 149
ENSMUSP00000133570 Homeodomain 15 71
ENSMUSP00000133570 Homeodomain 95 140
ENSMUSP00000134001 Homeodomain 15 71
ENSMUSP00000134483 Homeodomain 15 71
ENSMUSP00000134483 Homeodomain 95 149

Links

Other Homeodomain family TFs
Other Mus musculus TFs

Invalid Input OrderBy

7 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action