CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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Dbx1
(
Rattus norvegicus
)
Homeodomain
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00046 (Homeobox)
IPR001356
ENSRNOG00000014706
T215407_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Predicted to enable DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in cell differentiation in spinal cord and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within ventral spinal cord interneuron specification. Predicted to be located in nucleus. Orthologous to human DBX1 (developing brain homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Dbx1
M00451_2.00
Mus musculus
WTTAATTA
TAATTAAW
PBM
Berger et al.(2008)
Dbx1_3486
0.867
1.000
Dbx2
M00499_2.00
Mus musculus
NNDTNNN
NNNAHNN
PBM
Berger et al.(2008)
Dbx2_3487
0.830
0.857
Dbx
M02128_2.00
Drosophila melanogaster
WTTAATTA
TAATTAAW
PBM
Weirauch et al.(2014)
pTH6051
0.818
0.875
Dbx
M06550_2.00
Drosophila melanogaster
TTWATKA
TMATWAA
B1H
Mathelier et al.(2014)
MA0174.1
0.818
0.875
Hlx
M00485_2.00
Mus musculus
NNNAWND
HNWTNNN
PBM
Berger et al.(2008)
Hlx1_2350
0.733
0.696
H2.0
M06489_2.00
Drosophila melanogaster
WTWATDA
THATWAW
B1H
Mathelier et al.(2014)
MA0448.1
0.732
0.696
H2.0
M06250_2.00
Drosophila melanogaster
TWWWWDA
THAWWWA
B1H
Zhu et al.(2011)
H2.0_Cell_FBgn0001170
0.732
0.696
H2.0
M06251_2.00
Drosophila melanogaster
WTWATTRN
NYAATWAW
B1H
Zhu et al.(2011)
H2.0_SOLEXA_FBgn0001170
0.732
0.696
For this family, TFs with SR scores >
0.599
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSRNOP00000019739
Homeodomain
183
238
LRRAVFSDVQRKALEKTFQKQKYISKPDRKKLASKLGLKDSQVKIWFQNRRMKWRN
Links
Other
Homeodomain
family TFs
Other
Rattus norvegicus
TFs
270 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy