ISCW020063 (Ixodes scapularis)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ISCW020063 T219724_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
scro
M03854_2.00
Drosophila melanogaster
NNBRMGTGB

VCACKYVNN
SELEX
Nitta et al.(2015)
scro_1
0.862 0.982
ceh-24
M02181_2.00
Caenorhabditis elegans
NNRAKWRNN

NNYWMTYNN
PBM
Weirauch et al.(2014)
pTH6327
0.853 0.877
Nkx2-1
M00385_2.00
Mus musculus
NNRAGDRN

NYHCTYNN
PBM
Berger et al.(2008)
Titf1_1722
0.839 0.947
Nkx2-4
M00514_2.00
Mus musculus
NNRAGDRBNN

NNVYHCTYNN
PBM
Berger et al.(2008)
Nkx2-4_3074
0.839 0.947
NKX2-1
M09146_2.00
Homo sapiens
BTKGAGWGBN

NVCWCTCMAV
Misc
Kulakovskiy et al.(2013)
NKX21_HUMAN.H11MO.0.A
0.839 0.947
Nkx2-1
M09171_2.00
Mus musculus
NBTKGAGWGB

VCWCTCMAVN
Misc
Kulakovskiy et al.(2013)
NKX21_MOUSE.H11MO.0.A
0.839 0.947
Nkx2-1
M09563_2.00
Mus musculus
BTBRAGWGBH

DVCWCTYVAV
Misc
Heinz et al.(2010)
LungAC-Nkx2.1_GSE43252
0.839 0.947
NKX2-1
M10694_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TITF1_Q3
0.839 0.947
NKX2-1
M10695_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TTF1_Q5_01
0.839 0.947
NKX2-1
M10696_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TTF1_Q5
0.839 0.947
NKX2-1
M10697_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TTF1_Q6
0.839 0.947
NKX2-5
M00323_2.00
Homo sapiens
NWYAAGTGSNN

NNSCACTTRWN
PBM
Barrera et al.(2016)
NKX2-5_REF
0.803 0.825
Nkx2-5
M00404_2.00
Mus musculus
NNNRAGDRBN

NVYHCTYNNN
PBM
Berger et al.(2008)
Nkx2-5_3436
0.803 0.825
NKX2-5
M05346_2.00
Homo sapiens
BHYAAGTGBN

NVCACTTRDV
SELEX
Yin et al.(2017)
NKX2-5_FL_HT-SELEX
0.803 0.825
Nkx2-5
M02686_2.00
Mus musculus
WTAAKWK

MWMTTAW
SELEX
Mathelier et al.(2014)
MA0063.1
0.803 0.825
Nkx2-5
M08136_2.00
Mus musculus
SYTGAGWGSYH

DRSCWCTCARS
ChIP-seq
Mathelier et al.(2014)
MA0503.1
0.803 0.825
NKX2-5
M09163_2.00
Homo sapiens
BKRAGWGV

BCWCTYMV
Misc
Kulakovskiy et al.(2013)
NKX25_HUMAN.H11MO.0.B
0.803 0.825
Nkx2-5
M09177_2.00
Mus musculus
NBYBRAGTGS

SCACTYVRVN
Misc
Kulakovskiy et al.(2013)
NKX25_MOUSE.H11MO.0.A
0.803 0.825
Nkx2-5
M09567_2.00
Mus musculus
HBRAGWGBNN

NNVCWCTYVD
Misc
Heinz et al.(2010)
HL1-Nkx2.5.biotin_GSE21529
0.803 0.825
NKX2-5
M10742_2.00
Homo sapiens
TYAAGTG

CACTTRA
Transfac
Matys et al.(2006)
V$NKX25_01
0.803 0.825
NKX2-5
M10743_2.00
Homo sapiens
CWTAATTV

BAATTAWG
Transfac
Matys et al.(2006)
V$NKX25_02
0.803 0.825
NKX2-5
M10744_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NKX25_Q5
0.803 0.825
NKX2-5
M10745_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NKX25_Q6
0.803 0.825
NKX2-5
M00321_2.00
Homo sapiens
HNAAGTRBNN

NNVYACTTND
PBM
Barrera et al.(2016)
NKX2-5_R161P
0.803 0.825
NKX2-5
M05347_2.00
Homo sapiens
BTYAAGTGGN

NCCACTTRAV
SELEX
Yin et al.(2017)
NKX2-5_FL_Methyl-HT-SELEX_1
0.803 0.825
NKX2-5
M05348_2.00
Homo sapiens
BTYAACGAB

VTCGTTRAV
SELEX
Yin et al.(2017)
NKX2-5_FL_Methyl-HT-SELEX_2
0.803 0.825
NKX2-5
M00322_2.00
Homo sapiens
NNNRNNN

NNNYNNN
PBM
Barrera et al.(2016)
NKX2-5_R190C
0.803 0.807
NKX2-5
M00324_2.00
Homo sapiens
NHNNNNN

NNNNNDN
PBM
Barrera et al.(2016)
NKX2-5_T178M
0.803 0.807
Nkx2-3
M00497_2.00
Mus musculus
NNRAGDRNN

NNYHCTYNN
PBM
Berger et al.(2008)
Nkx2-3_3435
0.801 0.842
NKX2-3
M05042_2.00
Homo sapiens
NNBAAGTGBN

NVCACTTVNN
SELEX
Yin et al.(2017)
NKX2-3_eDBD_HT-SELEX
0.801 0.842
NKX2-3
M05045_2.00
Homo sapiens
BNBAAGTGBN

NVCACTTVNV
SELEX
Yin et al.(2017)
NKX2-3_FL_HT-SELEX
0.801 0.842
NKX2-3
M05043_2.00
Homo sapiens
BNBAAGTGBN

NVCACTTVNV
SELEX
Yin et al.(2017)
NKX2-3_eDBD_Methyl-HT-SELEX_1
0.801 0.842
NKX2-3
M05044_2.00
Homo sapiens
SDYAACGHB

VDCGTTRHS
SELEX
Yin et al.(2017)
NKX2-3_eDBD_Methyl-HT-SELEX_2
0.801 0.842
NKX2-3
M05046_2.00
Homo sapiens
BNBAAGTGBN

NVCACTTVNV
SELEX
Yin et al.(2017)
NKX2-3_FL_Methyl-HT-SELEX_1
0.801 0.842
NKX2-3
M05047_2.00
Homo sapiens
SWYAACSHB

VDSGTTRWS
SELEX
Yin et al.(2017)
NKX2-3_FL_Methyl-HT-SELEX_2
0.801 0.842
ceh-28
M08210_2.00
Caenorhabditis elegans
AATCGATW

WATCGATT
ChIP-seq
Contrino et al.(2012)
Mw138
0.797 0.719
vnd
M06551_2.00
Drosophila melanogaster
WYTCAAGTR

YACTTGARW
B1H
Mathelier et al.(2014)
MA0253.1
0.794 0.895
vnd
M06377_2.00
Drosophila melanogaster
WYTCAAGTR

YACTTGARW
B1H
Zhu et al.(2011)
Vnd_Cell_FBgn0003986
0.794 0.895
vnd
M06378_2.00
Drosophila melanogaster
KYTSAAGWGY

RCWCTTSARM
B1H
Zhu et al.(2011)
vnd_FlyReg_FBgn0003986
0.794 0.895
vnd
M06379_2.00
Drosophila melanogaster
BTBAAGTR

YACTTVAV
B1H
Zhu et al.(2011)
Vnd_SOLEXA_FBgn0003986
0.794 0.895
vnd
M09683_2.00
Drosophila melanogaster
TCAAGTGB

VCACTTGA
Misc
Kulakovskiy et al.(2009)
vnd
0.794 0.895
Nkx2-2
M00438_2.00
Mus musculus
NNNRAGDRN

NYHCTYNNN
PBM
Berger et al.(2008)
Nkx2-2_2823
0.794 0.877
Nkx2-2
M09190_2.00
Mus musculus
NTBRAGWGBBN

NVVCWCTYVAN
Misc
Kulakovskiy et al.(2013)
NKX22_MOUSE.H11MO.0.A
0.794 0.877
NKX2-2
M10681_2.00
Homo sapiens
WTAAGTRBTT

AAVYACTTAW
Transfac
Matys et al.(2006)
V$NKX22_01
0.794 0.877
NKX2-2
M10682_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NKX2B_Q3_01
0.794 0.877
NKX2-2
M10683_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NKX2B_Q3
0.794 0.877
Nkx2-9
M00520_2.00
Mus musculus
NNNRAGDRBN

NVYHCTYNNN
PBM
Berger et al.(2008)
Nkx2-9_3082
0.787 0.807
Nkx2-9
M00800_2.00
Mus musculus
NNRAGDRBNN

NNVYHCTYNN
PBM
Weirauch et al.(2013)
pTH2842
0.787 0.807
Nkx2-9
M09215_2.00
Mus musculus
BTCAAGKRB

VYMCTTGAV
Misc
Kulakovskiy et al.(2013)
NKX28_MOUSE.H11MO.0.C
0.787 0.807
tin
M00559_2.00
Drosophila melanogaster
NWYAAGTGGNN

NNCCACTTRWN
PBM
Busser et al.(2012a)
Tin
0.771 0.649
tin
M03809_2.00
Drosophila melanogaster
BTYAAGTGSN

NSCACTTRAV
SELEX
Nitta et al.(2015)
tin_1
0.771 0.649
tin
M06284_2.00
Drosophila melanogaster
BTYAAGTG

CACTTRAV
B1H
Zhu et al.(2011)
Tin_Cell_FBgn0004110
0.771 0.649
tin
M06285_2.00
Drosophila melanogaster
BCTCAAGTGSVN

NBSCACTTGAGV
B1H
Zhu et al.(2011)
tin_FlyReg_FBgn0004110
0.771 0.649
tin
M06286_2.00
Drosophila melanogaster
BWYAAGTR

YACTTRWV
B1H
Zhu et al.(2011)
Tin_SOLEXA_FBgn0004110
0.771 0.649
tin
M08421_2.00
Drosophila melanogaster
DBTCRAGTGS

SCACTYGAVH
ChIP-chip
Mathelier et al.(2014)
MA0247.2
0.771 0.649
NKX2-5
M00320_2.00
Homo sapiens
NHBAAKWRN

NYWMTTVDN
PBM
Barrera et al.(2016)
NKX2-5_K183E
0.770 0.807
Nkx2-6
M00496_2.00
Mus musculus
HYAAGTRBNN

NNVYACTTRD
PBM
Berger et al.(2008)
Nkx2-6_3437
0.763 0.772
ceh-22
M00376_2.00
Caenorhabditis elegans
WBRAGTRBNN

NNVYACTYVW
PBM
Berger et al.(2006)
Ceh-22
0.761 0.825
NKX2-8
M00302_2.00
Homo sapiens
NNRAGDRB

VYHCTYNN
PBM
Barrera et al.(2016)
NKX2-8_REF
0.755 0.807
NKX2-8
M05149_2.00
Homo sapiens
BTSRAGTGBN

NVCACTYSAV
SELEX
Yin et al.(2017)
NKX2-8_FL_HT-SELEX
0.755 0.807
NKX2-8
M09145_2.00
Homo sapiens
BTCAAGKRB

VYMCTTGAV
Misc
Kulakovskiy et al.(2013)
NKX28_HUMAN.H11MO.0.C
0.755 0.807
NKX2-8
M05150_2.00
Homo sapiens
GCARTAACGACATC

GATGTCGTTAYTGC
SELEX
Yin et al.(2017)
NKX2-8_FL_Methyl-HT-SELEX_1
0.755 0.807
NKX2-8
M05151_2.00
Homo sapiens
BTSAAGTGBN

NVCACTTSAV
SELEX
Yin et al.(2017)
NKX2-8_FL_Methyl-HT-SELEX_2
0.755 0.807
NKX2-8
M05152_2.00
Homo sapiens
BTBAACGAB

VTCGTTVAV
SELEX
Yin et al.(2017)
NKX2-8_FL_Methyl-HT-SELEX_3
0.755 0.807
NKX2-8
M00301_2.00
Homo sapiens
NNRAKDRB

VYHMTYNN
PBM
Barrera et al.(2016)
NKX2-8_A94T
0.755 0.789
Q24782_9CNID
M02206_2.00
Eleutheria dichotoma
TTAATTAA

TTAATTAA
PBM
Weirauch et al.(2014)
pTH5486
0.612 0.509
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ISCW020063-PA Homeodomain 9 65

Links

Other Homeodomain family TFs
Other Ixodes scapularis TFs

832 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
29598.m000468 Ricinus communis 29598.m000468 I 0.000
AMTR_s00002p00268140 Amborella trichopoda AMTR_s00002p00268140 I 0.000
Aquca_017_00582 Aquilegia coerulea Aquca_017_00582 I 0.000
BZIP63 Arabidopsis thaliana AT5G28770 D 0.000
BGIOSGA037742 Oryza indica BGIOSGA037742 I 0.000
Bo2g151850 Brassica oleracea Bo2g151850 I 0.000
Bostr.25517s0001 Boechera stricta Bostr.25517s0001 I 0.000
Bra010010 Brassica rapa Bra010010 I 0.000
Cagra.5456s0001 Capsella grandiflora Cagra.5456s0001 I 0.000
Carubv10001450m.g Capsella rubella Carubv10001450m.g I 0.000
cassava18571.valid.m1 Manihot esculenta cassava18571.valid.m1 I 0.000
cassava22706.valid.m1 Manihot esculenta cassava22706.valid.m1 I 0.000
Ca_01234 Cicer arietinum Ca_01234 I 0.000
Ca_03753 Cicer arietinum Ca_03753 I 0.000
chr5.LjT29J15.10.nc Lotus japonicus chr5.LjT29J15.10.nc I 0.000
Ciclev10001051m.g Citrus clementina Ciclev10001051m.g I 0.000
Ciclev10020133m.g Citrus clementina Ciclev10020133m.g I 0.000
Cla020112 Citrullus lanatus Cla020112 I 0.000
CPRF2_PETCR Petroselinum crispum CPRF2_PETCR D 0.000
Cucsa.133290 Cucumis sativus Cucsa.133290 I 0.000
estExt_fgenesh1_pg.C_2060068 Physcomitrella patens estExt_fgenesh1_pg.C_2060068 I 0.000
estExt_Genewise1.C_2060077 Physcomitrella patens estExt_Genewise1.C_2060077 D 0.000
Eucgr.H04338 Eucalyptus grandis Eucgr.H04338 I 0.000
gene16561-v1.0-hybrid Fragaria vesca gene16561-v1.0-hybrid I 0.000
GLYMA03G40730 Glycine max GLYMA03G40730 I 0.000
GLYMA10G30410 Glycine max GLYMA10G30410 I 0.000
GLYMA19G43420 Glycine max GLYMA19G43420 I 0.000
GLYMA20G36750 Glycine max GLYMA20G36750 I 0.000
Gorai.001G000600 Gossypium raimondii Gorai.001G000600 I 0.000
Gorai.004G246700 Gossypium raimondii Gorai.004G246700 I 0.000
Gorai.007G277300 Gossypium raimondii Gorai.007G277300 I 0.000
GSMUA_Achr10G08670_001 Musa acuminata GSMUA_Achr10G08670_001 I 0.000
GSMUA_Achr4G28530_001 Musa acuminata GSMUA_Achr4G28530_001 I 0.000
LPERR12G15130 Leersia perrieri LPERR12G15130 I 0.000
Lus10006590.g Linum usitatissimum Lus10006590.g I 0.000
Lus10015913.g Linum usitatissimum Lus10015913.g I 0.000
MDP0000270365 Malus domestica MDP0000270365 I 0.000
mgf004063m Mimulus guttatus mgf004063m N 0.000
mgf009803m Mimulus guttatus mgf009803m I 0.000
mgf012838m Mimulus guttatus mgf012838m I 0.000
MTR_1g080920 Medicago truncatula MTR_1g080920 I 0.000
MTR_7g115120 Medicago truncatula MTR_7g115120 I 0.000
OB02G14920 Oryza brachyantha OB02G14920 I 0.000
OB02G19520 Oryza brachyantha OB02G19520 I 0.000
OB12G24740 Oryza brachyantha OB12G24740 I 0.000
OBART12G18120 Oryza barthii OBART12G18120 I 0.000
OGLUM12G19660 Oryza glumaepatula OGLUM12G19660 I 0.000
ONIVA12G16860 Oryza nivara ONIVA12G16860 I 0.000
OPUNC12G16360 Oryza punctata OPUNC12G16360 I 0.000
orange1.1g012287m.g Citrus sinensis orange1.1g012287m.g I 0.000
orange1.1g013166m.g Citrus sinensis orange1.1g013166m.g I 0.000
ORUFI12G20050 Oryza rufipogon ORUFI12G20050 I 0.000
OS12G0601800 Oryza sativa OS12G0601800 I 0.000
PGSC0003DMG400019455 Solanum tuberosum PGSC0003DMG400019455 I 0.000
PK05128.1 Cannabis sativa PK05128.1 D 0.000
Pm003522 Prunus mume Pm003522 I 0.000
POPTR_0006s29250 Populus trichocarpa POPTR_0006s29250 I 0.000
POPTR_0013s03800 Populus trichocarpa POPTR_0013s03800 I 0.000
PRUPE_ppa005585mg Prunus persica PRUPE_ppa005585mg I 0.000
SapurV1A.0110s0140 Salix purpurea SapurV1A.0110s0140 I 0.000
SapurV1A.0729s0180 Salix purpurea SapurV1A.0729s0180 I 0.000
SELMODRAFT_270282 Selaginella moellendorffii SELMODRAFT_270282 I 0.000
SELMODRAFT_439017 Selaginella moellendorffii SELMODRAFT_439017 I 0.000
Solyc01g097330.2 Solanum lycopersicum Solyc01g097330.2 I 0.000
TCM_026349 Theobroma cacao TCM_026349 I 0.000
BZO2H3 Vitis vinifera VIT_14s0030g02200 I 0.000