ENSP00000371875 (Macaca fascicularis)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00046 (Homeobox) IPR001356 ENSP00000371875 T226110_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a member of the NK family of homeobox-containing proteins. The encoded protein may play a role in skeletal development. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Nkx3-2
M00506_2.00
Mus musculus
NNRAGDRNN

NNYHCTYNN
PBM
Berger et al.(2008)
Bapx1_2343
0.850 0.965
NKX3-2
M05012_2.00
Homo sapiens
NNTAAGTGSN

NSCACTTANN
SELEX
Yin et al.(2017)
NKX3-2_eDBD_HT-SELEX
0.850 0.965
NKX3-2
M09138_2.00
Homo sapiens
TTAAGTGBNH

DNVCACTTAA
Misc
Kulakovskiy et al.(2013)
NKX32_HUMAN.H11MO.0.C
0.850 0.965
Nkx3-2
M09212_2.00
Mus musculus
TTAAGTGBNH

DNVCACTTAA
Misc
Kulakovskiy et al.(2013)
NKX32_MOUSE.H11MO.0.B
0.850 0.965
NKX3-2
M10663_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NKX32_01
0.850 0.965
NKX3-2
M05013_2.00
Homo sapiens
NNTAAGTGBN

NVCACTTANN
SELEX
Yin et al.(2017)
NKX3-2_eDBD_Methyl-HT-SELEX_1
0.850 0.965
NKX3-2
M05014_2.00
Homo sapiens
NTAACGHB

VDCGTTAN
SELEX
Yin et al.(2017)
NKX3-2_eDBD_Methyl-HT-SELEX_2
0.850 0.965
bap
M00560_2.00
Drosophila melanogaster
NDAAGTRBNN

NNVYACTTHN
PBM
Busser et al.(2012a)
Bap
0.839 0.842
bap
M02119_2.00
Drosophila melanogaster
NYTAAGTRSNN

NNSYACTTARN
PBM
Weirauch et al.(2014)
pTH5945
0.839 0.842
bap
M03812_2.00
Drosophila melanogaster
NNTAAGTGBN

NVCACTTANN
SELEX
Nitta et al.(2015)
bap_1
0.839 0.842
bap
M06504_2.00
Drosophila melanogaster
TTAAGTR

YACTTAA
B1H
Mathelier et al.(2014)
MA0211.1
0.839 0.842
bap
M06287_2.00
Drosophila melanogaster
NBTTAAGTRN

NYACTTAAVN
B1H
Zhu et al.(2011)
Bap_Cell_FBgn0004862
0.839 0.842
bap
M06288_2.00
Drosophila melanogaster
NYTAAKTR

YAMTTARN
B1H
Zhu et al.(2011)
Bap_SOLEXA_FBgn0004862
0.839 0.842
Nkx3-1
M00170_2.00
Mus musculus
NDAAGTRBNN

NNVYACTTHN
PBM
Badis et al.(2009)
Nkx3-1_2923
0.822 0.807
Nkx3-1
M00420_2.00
Mus musculus
NNAAGTRBNN

NNVYACTTNN
PBM
Berger et al.(2008)
Nkx3-1_2923
0.822 0.807
NKX3-1
M05255_2.00
Homo sapiens
NNTAAGTGSN

NSCACTTANN
SELEX
Yin et al.(2017)
NKX3-1_eDBD_HT-SELEX
0.822 0.807
NKX3-1
M09154_2.00
Homo sapiens
NYDAAGTGBYWD

HWRVCACTTHRN
Misc
Kulakovskiy et al.(2013)
NKX31_HUMAN.H11MO.0.C
0.822 0.807
Nkx3-1
M09184_2.00
Mus musculus
NYDAAGTGBYWD

HWRVCACTTHRN
Misc
Kulakovskiy et al.(2013)
NKX31_MOUSE.H11MO.0.C
0.822 0.807
NKX3-1
M09559_2.00
Homo sapiens
BTRAGTRBYY

RRVYACTYAV
Misc
Heinz et al.(2010)
LNCaP-Nkx3.1_GSE28264
0.822 0.807
NKX3-1
M10729_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
P$GT1_Q6_01
0.822 0.807
NKX3-1
M10730_2.00
Homo sapiens
NWWTAAGTATWH

DWATACTTAWWN
Transfac
Matys et al.(2006)
V$NKX3A_01
0.822 0.807
NKX3-1
M10731_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NKX3A_Q3
0.822 0.807
NKX3-1
M05256_2.00
Homo sapiens
NNTAAGTGBN

NVCACTTANN
SELEX
Yin et al.(2017)
NKX3-1_eDBD_Methyl-HT-SELEX_1
0.822 0.807
NKX3-1
M05257_2.00
Homo sapiens
NTAAYSWB

VWSRTTAN
SELEX
Yin et al.(2017)
NKX3-1_eDBD_Methyl-HT-SELEX_2
0.822 0.807
ENSCING00000007395
M02076_2.00
Ciona intestinalis
NNNDWNWR

YWNWHNNN
PBM
Weirauch et al.(2014)
pTH5922
0.808 0.649
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000371875 Homeodomain 86 142

Links

Other Homeodomain family TFs
Other Macaca fascicularis TFs

222 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
NKX3-2 Homo sapiens ENSG00000109705 D 0.850
nkx3-2 Xenopus tropicalis XB-GENE-876834 I 0.850
nkx3.2 Oryzias latipes ENSORLG00000000593 I 0.850
ENSOPRG00000005452 Ochotona princeps ENSOPRG00000005452 I 0.850
NKX3-2 Gorilla gorilla ENSGGOG00000008589 I 0.850
nkx3.2 Gasterosteus aculeatus ENSGACG00000016378 I 0.850
ENSEEUG00000012691 Erinaceus europaeus ENSEEUG00000012691 I 0.850
nkx3-2.S Xenopus laevis XB-GENE-876836 I 0.850
nkx3.2 Danio rerio ENSDARG00000037639 I 0.850
ENSCSAG00000016338 Chlorocebus sabaeus ENSCSAG00000016338 I 0.850
ENSPFOG00000002882 Poecilia formosa ENSPFOG00000002882 I 0.850
Alligator_sinensis_CCG000534.1 Alligator sinensis Alligator_sinensis_CCG000534.1 I 0.850
ENSPANG00000021310 Papio anubis ENSPANG00000021310 I 0.850
NKX3-2 Procavia capensis ENSPCAG00000013077 I 0.850
ENSGMOG00000018725 Gadus morhua ENSGMOG00000018725 I 0.850
ENSLACG00000003608 Latimeria chalumnae ENSLACG00000003608 I 0.850
ENSMPUG00000000476 Mustela putorius furo ENSMPUG00000000476 I 0.850
NKX3-2 Monodelphis domestica ENSMODG00000024753 I 0.850
NKX3-2 Otolemur garnettii ENSOGAG00000015615 I 0.850
Nkx3-2 Mus musculus ENSMUSG00000049691 D 0.850
ENSNLEG00000016256 Nomascus leucogenys ENSNLEG00000016256 I 0.850
NKX3-2 Oryctolagus cuniculus ENSOCUG00000009039 I 0.850
Pvit_15821 Pogona vitticeps Pvit_15821 I 0.850
ENSMMUG00000022026 Macaca mulatta ENSMMUG00000022026 I 0.850
ENSLOCG00000009892 Lepisosteus oculatus ENSLOCG00000009892 I 0.850
NKX3-2 Loxodonta africana ENSLAFG00000031404 I 0.850
ENSONIG00000002379 Oreochromis niloticus ENSONIG00000002379 I 0.850
ENSMICG00000000190 Microcebus murinus ENSMICG00000000190 I 0.850
NKX3-2 Myotis lucifugus ENSMLUG00000008362 I 0.850
ENSPPYG00000014611 Pongo abelii ENSPPYG00000014611 I 0.850
NKX3-2 Dasypus novemcinctus ENSDNOG00000043074 I 0.850
ENSSTOG00000021803 Ictidomys tridecemlineatus ENSSTOG00000021803 I 0.850
ENSSSCG00000024594 Sus scrofa ENSSSCG00000024594 I 0.850
Nkx3-2 Rattus norvegicus ENSRNOG00000060782 I 0.850
NKX3-2 Bos taurus ENSBTAG00000010896 I 0.850
NKX3-2 Cavia porcellus ENSCPOG00000005449 I 0.850
ENSAMEG00000009342 Ailuropoda melanoleuca ENSAMEG00000009342 I 0.850
ENSXMAG00000016282 Xiphophorus maculatus ENSXMAG00000016282 I 0.850
ENSTTRG00000003623 Tursiops truncatus ENSTTRG00000003623 I 0.850
nkx3.2 Takifugu rubripes ENSTRUG00000014438 I 0.850
NKX3-2 Canis familiaris ENSCAFG00000015412 I 0.850
ENSAMXG00000003840 Astyanax mexicanus ENSAMXG00000003840 I 0.850
ENSPSIG00000012169 Pelodiscus sinensis ENSPSIG00000012169 I 0.850
ENSPTRG00000031253 Pan troglodytes ENSPTRG00000031253 I 0.850
NKX3-2 Callithrix jacchus ENSCJAG00000012159 I 0.850
NKX3-2 Pteropus vampyrus ENSPVAG00000002830 I 0.850
ACYPI002893 Acyrthosiphon pisum ACYPI002893 I 0.846
BGIBMGA010706 Bombyx mori BGIBMGA010706 I 0.844
KGM_11246 Danaus plexippus KGM_11246 I 0.844
MCINX004875 Melitaea cinxia MCINX004875 I 0.844
HMEL006181 Heliconius melpomene HMEL006181 I 0.844
nkx3-3.S Xenopus laevis XB-GENE-865322 I 0.844
CpipJ_CPIJ004109 Culex pipiens CpipJ_CPIJ004109 I 0.843
CPIJ004109 Culex quinquefasciatus CPIJ004109 I 0.843
PPAI010327 Phlebotomus papatasi PPAI010327 I 0.843
AAEL006597 Aedes aegypti AAEL006597 I 0.843
MESCA006298 Megaselia scalaris MESCA006298 I 0.843
LCUP000733 Lucilia cuprina LCUP000733 I 0.843
nkx3.2 Tetraodon nigroviridis ENSTNIG00000015732 I 0.841
bap Drosophila sechellia FBgn0067536 I 0.839
bap Drosophila simulans FBgn0067504 I 0.839
bap Drosophila melanogaster FBgn0004862 D 0.839
Sakowv30040088m.g Saccoglossus kowalevskii Sakowv30040088m.g I 0.839
GE25732 Drosophila yakuba FBgn0242790 I 0.839
SMAR005030 Strigamia maritima SMAR005030 I 0.839
GG24598 Drosophila erecta FBgn0116730 I 0.839
GF18600 Drosophila ananassae FBgn0095618 I 0.839
CGI_10023919 Crassostrea gigas CGI_10023919 I 0.838
estExt_fgenesh2_pg.C_1430013 Branchiostoma floridae estExt_fgenesh2_pg.C_1430013 I 0.838
SPU_013047 Strongylocentrotus purpuratus SPU_013047 I 0.838
RPRC001122 Rhodnius prolixus RPRC001122 I 0.837
ENSLACG00000012763 Latimeria chalumnae ENSLACG00000012763 I 0.837
CLEC002956 Cimex lectularius CLEC002956 I 0.836
NEMVEDRAFT_v1g208034 Nematostella vectensis NEMVEDRAFT_v1g208034 I 0.833
PHUM439840 Pediculus humanus PHUM439840 I 0.833
nkx3-1 Oryzias latipes ENSORLG00000010925 I 0.833
Ocbimv22026957m.g Octopus bimaculoides Ocbimv22026957m.g I 0.833
nkx3.3 Danio rerio ENSDARG00000069327 I 0.833
ADIR005347 Anopheles dirus ADIR005347 I 0.832
AEPI001627 Anopheles epiroticus AEPI001627 I 0.832
ACUA019412 Anopheles culicifacies ACUA019412 I 0.832
ASTEI07437 Anopheles stephensi ASTEI07437 I 0.832
ACOM028774 Anopheles coluzzii ACOM028774 I 0.832
ENSAMXG00000002250 Astyanax mexicanus ENSAMXG00000002250 I 0.832
ENSPFOG00000020885 Poecilia formosa ENSPFOG00000020885 I 0.832
AFAF013479 Anopheles farauti AFAF013479 I 0.832
AMEM005009 Anopheles merus AMEM005009 I 0.832
AQUA001538 Anopheles quadriannulatus AQUA001538 I 0.832
AMEC017317 Anopheles melas AMEC017317 I 0.832
ASIS007650 Anopheles sinensis ASIS007650 I 0.832
AFUN008966 Anopheles funestus AFUN008966 I 0.832
AMAM011860 Anopheles maculatus AMAM011860 I 0.832
AMIN004031 Anopheles minimus AMIN004031 I 0.832
ACHR006588 Anopheles christyi ACHR006588 I 0.832
ENSLOCG00000015015 Lepisosteus oculatus ENSLOCG00000015015 I 0.832
ENSLOCG00000009031 Lepisosteus oculatus ENSLOCG00000009031 I 0.832
AGAP003671 Anopheles gambiae AGAP003671 I 0.832
ADAC003526 Anopheles darlingi ADAC003526 I 0.832
ENSXMAG00000020095 Xiphophorus maculatus ENSXMAG00000020095 I 0.832
AATE016309 Anopheles atroparvus AATE016309 I 0.832
MDOA010758 Musca domestica MDOA010758 I 0.832
nkx3-3 Xenopus tropicalis XB-GENE-479908 I 0.832
AARA010121 Anopheles arabiensis AARA010121 I 0.832
ENSORLG00000007716 Oryzias latipes ENSORLG00000007716 I 0.832
HelroG148616 Helobdella robusta HelroG148616 I 0.830
nkx3.3 Gasterosteus aculeatus ENSGACG00000007573 I 0.830
nkx3-1.L Xenopus laevis XB-GENE-479031 I 0.829
XP_002932598 Xenopus tropicalis XP_002932598 I 0.829
nkx3-1.S Xenopus laevis XB-GENE-6252708 I 0.829
CapteG79432 Capitella teleta CapteG79432 I 0.828
ISCW014989 Ixodes scapularis ISCW014989 I 0.828
NV25828 Nasonia vitripennis NV25828 I 0.827
ENSAMXG00000024837 Astyanax mexicanus ENSAMXG00000024837 I 0.827
SINV22315 Solenopsis invicta SINV22315 I 0.827
GA20672 Drosophila pseudoobscura FBgn0080666 I 0.827
Hsal_06436--XP_001120208.1_APIME Harpegnathos saltator Hsal_06436--XP_001120208.1_APIME I 0.827
ACEP23863 Atta cephalotes ACEP23863 I 0.827
GH22032 Drosophila grimshawi FBgn0129493 I 0.827
GK14503 Drosophila willistoni FBgn0216509 I 0.827
GJ14311 Drosophila virilis FBgn0201526 I 0.827
GB47401 Apis mellifera GB47401 I 0.827
GL27337 Drosophila persimilis FBgn0164918 I 0.827
GI21951 Drosophila mojavensis FBgn0144680 I 0.827
LotgiG60615 Lottia gigantea LotgiG60615 I 0.823
ENSP00000370253 Macaca fascicularis ENSP00000370253 I 0.822
ENSBTAP00000001615-D1 Bos grunniens ENSBTAP00000001615-D1 I 0.822
Myotis_brandtii_NKX3_10014306 Myotis brandtii Myotis_brandtii_NKX3_10014306 I 0.822
ENSSHAG00000015475 Sarcophilus harrisii ENSSHAG00000015475 I 0.822
NKX3-1 Macaca mulatta ENSMMUG00000009796 I 0.822
NKX3-1 Monodelphis domestica ENSMODG00000016789 I 0.822
NKX3-1 Myotis lucifugus ENSMLUG00000006118 I 0.822
NKX3-1 Microcebus murinus ENSMICG00000011189 I 0.822
NKX3-1 Loxodonta africana ENSLAFG00000008941 I 0.822
ENSMPUG00000003418 Mustela putorius furo ENSMPUG00000003418 I 0.822
Nkx3-1 Mus musculus ENSMUSG00000022061 D 0.822
NKX3-1 Oryctolagus cuniculus ENSOCUG00000004294 I 0.822
ENSOARG00000010071 Ovis aries ENSOARG00000010071 I 0.822
NKX3-1 Ornithorhynchus anatinus ENSOANG00000008027 I 0.822
ENSNLEG00000015968 Nomascus leucogenys ENSNLEG00000015968 I 0.822
NKX3-1 Homo sapiens ENSG00000167034 D 0.822
NKX3-1 Echinops telfairi ENSETEG00000018790 I 0.822
ENSCAFG00000009107 Canis familiaris ENSCAFG00000009107 I 0.822
NKX3-1 Bos taurus ENSBTAG00000001221 I 0.822
ENSAMEG00000002866 Ailuropoda melanoleuca ENSAMEG00000002866 I 0.822
ENSACAG00000026683 Anolis carolinensis ENSACAG00000026683 I 0.822
ENSCHOG00000011132 Choloepus hoffmanni ENSCHOG00000011132 I 0.822
NKX3-1 Callithrix jacchus ENSCJAG00000020092 I 0.822
NKX3-1 Erinaceus europaeus ENSEEUG00000001113 I 0.822
NKX3-1 Dasypus novemcinctus ENSDNOG00000044451 I 0.822
ENSCSAG00000016229 Chlorocebus sabaeus ENSCSAG00000016229 I 0.822
ENSCPOG00000010557 Cavia porcellus ENSCPOG00000010557 I 0.822
NKX3-1 Otolemur garnettii ENSOGAG00000001303 I 0.822
NKX3-1 Gorilla gorilla ENSGGOG00000014369 I 0.822
NKX3-1 Pteropus vampyrus ENSPVAG00000005378 I 0.822
NKX3-1 Pan troglodytes ENSPTRG00000020081 I 0.822
ENSPPYG00000018442 Pongo abelii ENSPPYG00000018442 I 0.822
Nkx3-1 Rattus norvegicus ENSRNOG00000015477 I 0.822
ENSSSCG00000028216 Sus scrofa ENSSSCG00000028216 I 0.822
NKX3-1 Vicugna pacos ENSVPAG00000004503 I 0.822
ENSTSYG00000007109 Tarsius syrichta ENSTSYG00000007109 I 0.822
ENSTBEG00000002319 Tupaia belangeri ENSTBEG00000002319 I 0.822
ENSPCAG00000016644 Procavia capensis ENSPCAG00000016644 I 0.822
ENSSARG00000001895 Sorex araneus ENSSARG00000001895 I 0.822
ENSPANG00000004934 Papio anubis ENSPANG00000004934 I 0.822
NKX3-1 Ochotona princeps ENSOPRG00000003179 I 0.822
nkx3-1 Gasterosteus aculeatus ENSGACG00000010776 I 0.821
ENSONIG00000011762 Oreochromis niloticus ENSONIG00000011762 I 0.821
ENSGMOG00000005518 Gadus morhua ENSGMOG00000005518 I 0.821
ENSXMAG00000020262 Xiphophorus maculatus ENSXMAG00000020262 I 0.820
ENSFALG00000011121 Ficedula albicollis ENSFALG00000011121 I 0.820
ENSAPLG00000014690 Anas platyrhynchos ENSAPLG00000014690 I 0.820
nkx3-1 Danio rerio ENSDARG00000078280 I 0.820
ENSPFOG00000009654 Poecilia formosa ENSPFOG00000009654 I 0.820
tetur04g08350 Tetranychus urticae tetur04g08350 I 0.819
TC012743 Tribolium castaneum TC012743 I 0.819
YQE_10102 Dendroctonus ponderosae YQE_10102 I 0.819
LDEC009723 Leptinotarsa decemlineata LDEC009723 I 0.819
ENSECAG00000001509 Equus caballus ENSECAG00000001509 I 0.818
ENSPSIG00000017342 Pelodiscus sinensis ENSPSIG00000017342 I 0.818
ENSCING00000007395 Ciona intestinalis ENSCING00000007395 D 0.808
SMU15003549 Schmidtea mediterranea SMU15003549 I 0.808
BGLB010692 Biomphalaria glabrata BGLB010692 I 0.805
csin109461 Clonorchis sinensis csin109461 I 0.803
Smp_140730 Schistosoma mansoni Smp_140730 I 0.803
A_02450 Schistosoma haematobium A_02450 I 0.803
SMRZ_0000016501 Schistosoma margrebowiei SMRZ_0000016501 I 0.803
SMTD_0000549701 Schistosoma mattheei SMTD_0000549701 I 0.803
PXEA_0003190801 Protopolystoma xenopodis PXEA_0003190801 I 0.793
TCLT_0000478201 Thelazia callipaeda TCLT_0000478201 I 0.738
Aan_R009530 Calypte anna Aan_R009530 I 0.703
ENSONIG00000018347 Oreochromis niloticus ENSONIG00000018347 I 0.694
ENSTTRG00000012332 Tursiops truncatus ENSTTRG00000012332 I 0.683
D915_02578 Fasciola hepatica D915_02578 I 0.680
MCOS_0000074801 Mesocestoides corti MCOS_0000074801 I 0.660
HelroG138724 Helobdella robusta HelroG138724 I 0.651
ENSAMXG00000009415 Astyanax mexicanus ENSAMXG00000009415 I 0.645
D918_06873 Trichuris suis D918_06873 I 0.629
TTRE_0000463801 Trichuris trichiura TTRE_0000463801 I 0.629
BTMF_0000772101 Brugia timori BTMF_0000772101 I 0.625
EmuJ_000895600 Echinococcus multilocularis EmuJ_000895600 I 0.624
TsM_000540100 Taenia solium TsM_000540100 I 0.624
ECANG7_00763 Echinococcus canadensis ECANG7_00763 I 0.624
TTAC_0000184701 Hydatigera taeniaeformis TTAC_0000184701 I 0.624
TASK_0000475201 Taenia asiatica TASK_0000475201 I 0.624
nLs.2.1.2.g07743 Litomosoides sigmodontis nLs.2.1.2.g07743 I 0.623
CGOC_0001018301 Cylicostephanus goldi CGOC_0001018301 I 0.620
ASIM_0001224701 Anisakis simplex ASIM_0001224701 I 0.614
Minc11316 Meloidogyne incognita Minc11316 I 0.613
L893_g18140 Steinernema glaseri L893_g18140 I 0.612
WUBG_10043 Wuchereria bancrofti WUBG_10043 I 0.611
ENSTGUG00000004550 Taeniopygia guttata ENSTGUG00000004550 I 0.610
NKX2-3 Takifugu rubripes ENSTRUG00000002729 I 0.608
ENSPFOG00000009440 Poecilia formosa ENSPFOG00000009440 I 0.608
ENSONIG00000000279 Oreochromis niloticus ENSONIG00000000279 I 0.608
NKX2-3 Takifugu rubripes ENSTRUG00000003800 I 0.608
ENSXMAG00000005680 Xiphophorus maculatus ENSXMAG00000005680 I 0.608
ENSAMXG00000015414 Astyanax mexicanus ENSAMXG00000015414 I 0.607
NKX2-6 Pteropus vampyrus ENSPVAG00000005380 I 0.605
NKX2-6 Equus caballus ENSECAG00000013714 I 0.605
NKX2-6 Canis familiaris ENSCAFG00000024691 I 0.605
A_06201 Schistosoma haematobium A_06201 I 0.603
hlx Ciona intestinalis ENSCING00000019191 I 0.602