|
|
HHAL002696-PA
(Halyomorpha halys)
Homeodomain
|
TF Information |
|---|
| Pfam ID |
Interpro ID |
Gene ID |
CIS-BP ID |
Sequence source |
| PF00046 (Homeobox) |
IPR001356 |
HHAL002696-PA |
T229832_2.00 |
Misc (2018-Jan-19) |
| NCBI Gene Info:This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] |
Directly determined binding motifs |
|---|
| Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR
Score |
DBD
Identity |
| No direct experiments |
|
|
|
|
|
Motifs from related TFs |
|---|
| Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR
Score |
DBD
Identity |
VAX1
M03168_2.00 |
Homo sapiens |
YTAATKAN |
NTMATTAR |
SELEX
Jolma et al.(2013)
VAX1_1
|
0.671
|
0.400
|
VAX1
M05182_2.00 |
Homo sapiens |
BTAATTRN |
NYAATTAV |
SELEX
Yin et al.(2017)
VAX1_eDBD_HT-SELEX
|
0.671
|
0.400
|
VAX1
M05183_2.00 |
Homo sapiens |
BTMATKRN |
NYMATKAV |
SELEX
Yin et al.(2017)
VAX1_eDBD_Methyl-HT-SELEX
|
0.671
|
0.400
|
VSX1
M03087_2.00 |
Homo sapiens |
YTAATTAN |
NTAATTAR |
SELEX
Jolma et al.(2013)
VSX1_1
|
0.615
|
0.289
|
VSX1
M03088_2.00 |
Homo sapiens |
NNYAATTRRBN |
NVYYAATTRNN |
SELEX
Jolma et al.(2013)
VSX1_2
|
0.615
|
0.289
|
VSX1
M04941_2.00 |
Homo sapiens |
YYAATTRN |
NYAATTRR |
SELEX
Yin et al.(2017)
VSX1_eDBD_HT-SELEX
|
0.615
|
0.289
|
VSX1
M04944_2.00 |
Homo sapiens |
NTAATTRS |
SYAATTAN |
SELEX
Yin et al.(2017)
VSX1_FL_HT-SELEX
|
0.615
|
0.289
|
VSX1
M05869_2.00 |
Homo sapiens |
DGCTAATTAN |
NTAATTAGCH |
SMiLE-seq
Isakova et al.(2017)
VSX1
|
0.615
|
0.289
|
VSX1
M04942_2.00 |
Homo sapiens |
NTAAYGMN |
NKCRTTAN |
SELEX
Yin et al.(2017)
VSX1_eDBD_Methyl-HT-SELEX_1
|
0.615
|
0.289
|
VSX1
M04943_2.00 |
Homo sapiens |
YYAATTRN |
NYAATTRR |
SELEX
Yin et al.(2017)
VSX1_eDBD_Methyl-HT-SELEX_2
|
0.615
|
0.289
|
VSX1
M04945_2.00 |
Homo sapiens |
NTAATTRG |
CYAATTAN |
SELEX
Yin et al.(2017)
VSX1_FL_Methyl-HT-SELEX_1
|
0.615
|
0.289
|
VSX1
M04946_2.00 |
Homo sapiens |
NTAAYGAN |
NTCRTTAN |
SELEX
Yin et al.(2017)
VSX1_FL_Methyl-HT-SELEX_2
|
0.615
|
0.289
|
| For this family, TFs with SR scores > 0.599 will likely have a similar motif |