TF Information

HHAL002779-PA *(Halyomorpha halys)* Homeodomain
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source
PF00046 (Homeobox)	IPR001356	HHAL002779-PA	T229834_2.00	Misc (2018-Jan-19)
NCBI Gene Info: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
NEMVEDRAFT_v1g136480 M02147_2.00	Nematostella vectensis	NNNNNNNNNN	NNNNNNNNNN	PBM Weirauch et al.(2014) pTH6103	0.702	0.544
Rax M00426_2.00	Mus musculus	NNTAATTRN	NYAATTANN	PBM Berger et al.(2008) Rax_3443	0.619	0.702
RAX M03149_2.00	Homo sapiens	NHTAATTRNN	NNYAATTADN	SELEX Jolma et al.(2013) RAX_1	0.619	0.702
Rx M03840_2.00	Drosophila melanogaster	BTAATTRV	BYAATTAV	SELEX Nitta et al.(2015) Rx_1	0.619	0.702
Rx M03841_2.00	Drosophila melanogaster	NTAATBNSATTAN	NTAATSNVATTAN	SELEX Nitta et al.(2015) Rx_2	0.619	0.702
RAX M05142_2.00	Homo sapiens	YYAATTRN	NYAATTRR	SELEX Yin et al.(2017) RAX_eDBD_HT-SELEX	0.619	0.702
Rx M06520_2.00	Drosophila melanogaster	YTAATTR	YAATTAR	B1H Mathelier et al.(2014) MA0202.1	0.619	0.702
Rx M06317_2.00	Drosophila melanogaster	VYTAATTR	YAATTARB	B1H Zhu et al.(2011) Rx_Cell_FBgn0020617	0.619	0.702
Rx M06318_2.00	Drosophila melanogaster	HTAATTR	YAATTAD	B1H Zhu et al.(2011) Rx_SOLEXA_FBgn0020617	0.619	0.702
Rax M10773_2.00	Rattus norvegicus	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$RAX_04	0.619	0.702
RAX M05143_2.00	Homo sapiens	NTAAYRNN	NNYRTTAN	SELEX Yin et al.(2017) RAX_eDBD_Methyl-HT-SELEX_1	0.619	0.702
RAX M05144_2.00	Homo sapiens	YYAATTRN	NYAATTRR	SELEX Yin et al.(2017) RAX_eDBD_Methyl-HT-SELEX_2	0.619	0.702
RAX2 M03214_2.00	Homo sapiens	NTAATTRN	NYAATTAN	SELEX Jolma et al.(2013) RAXL1_1	0.615	0.684
For this family, TFs with SR scores > 0.599* will likely have a similar motif*