|
HHAL003615-PA
(Halyomorpha halys)
Homeodomain
|
TF Information |
Pfam ID |
Interpro ID |
Gene ID |
CIS-BP ID |
Sequence source |
PF00046 (Homeobox) |
IPR001356 |
HHAL003615-PA |
T229837_2.00 |
Misc (2018-Jan-19) |
NCBI Gene Info:This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] |
Directly determined binding motifs |
Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR Score |
DBD Identity |
No direct experiments |
|
|
|
|
|
Motifs from related TFs |
Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR Score |
DBD Identity |
Six3
M00483_2.00 |
Mus musculus |
NNNAYMN |
NKRTNNN |
PBM
Berger et al.(2008)
Six3_1732
|
0.867
|
0.982
|
SIX3
M05159_2.00 |
Homo sapiens |
NNYGATABBN |
NVVTATCRNN |
SELEX
Yin et al.(2017)
SIX3_eDBD_HT-SELEX
|
0.867
|
0.982
|
SIX3
M10698_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$SIX3_Q6
|
0.867
|
0.982
|
SIX3
M05160_2.00 |
Homo sapiens |
NNYGATABVB |
VBVTATCRNN |
SELEX
Yin et al.(2017)
SIX3_eDBD_Methyl-HT-SELEX
|
0.867
|
0.982
|
Optix
M02124_2.00 |
Drosophila melanogaster |
NNNNNDATMN |
NKATHNNNNN |
PBM
Weirauch et al.(2014)
pTH5437
|
0.867
|
0.965
|
Optix
M03850_2.00 |
Drosophila melanogaster |
TAATYTAATTA |
TAATTARATTA |
SELEX
Nitta et al.(2015)
Optix_1
|
0.867
|
0.965
|
Optix
M06526_2.00 |
Drosophila melanogaster |
TGATA |
TATCA |
B1H
Mathelier et al.(2014)
MA0199.1
|
0.867
|
0.965
|
Optix
M06327_2.00 |
Drosophila melanogaster |
HHVTGATA |
TATCABDD |
B1H
Zhu et al.(2011)
Optix_Cell_FBgn0025360
|
0.867
|
0.965
|
Optix
M06328_2.00 |
Drosophila melanogaster |
NNNTGATA |
TATCANNN |
B1H
Zhu et al.(2011)
Optix_SOLEXA_FBgn0025360
|
0.867
|
0.965
|
SIX6
M00326_2.00 |
Homo sapiens |
NNDATMB |
VKATHNN |
PBM
Barrera et al.(2016)
SIX6_REF
|
0.865
|
0.965
|
Six6
M00169_2.00 |
Mus musculus |
NNAYMNN |
NNKRTNN |
PBM
Badis et al.(2009)
Six6_2267
|
0.865
|
0.965
|
Six6
M00412_2.00 |
Mus musculus |
NNNTGATAYCN |
NGRTATCANNN |
PBM
Berger et al.(2008)
Six6_2267
|
0.865
|
0.965
|
SIX6
M05357_2.00 |
Homo sapiens |
NNYGATASVB |
VBSTATCRNN |
SELEX
Yin et al.(2017)
SIX6_eDBD_HT-SELEX
|
0.865
|
0.965
|
SIX6
M00325_2.00 |
Homo sapiens |
NNNDATMB |
VKATHNNN |
PBM
Barrera et al.(2016)
SIX6_H141N
|
0.865
|
0.965
|
SIX6
M05358_2.00 |
Homo sapiens |
VBVYAYCRNN |
NNYGRTRBVB |
SELEX
Yin et al.(2017)
SIX6_eDBD_Methyl-HT-SELEX
|
0.865
|
0.965
|
six3
M02102_2.00 |
Oryzias latipes |
NNDAYMBNNN |
NNNVKRTHNN |
PBM
Weirauch et al.(2014)
pTH5928
|
0.865
|
0.947
|
SIX6
M00327_2.00 |
Homo sapiens |
NHDAYMBNN |
NNVKRTHDN |
PBM
Barrera et al.(2016)
SIX6_T165A
|
0.859
|
0.947
|
For this family, TFs with SR scores > 0.599 will likely have a similar motif |