HHAL008908-PA (Halyomorpha halys)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00046 (Homeobox) IPR001356 HHAL008908-PA T229859_2.00 Misc (2018-Jan-19)
NCBI Gene Info:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
dve
M03837_2.00
Drosophila melanogaster
VHTAATTADB

VHTAATTADB
SELEX
Nitta et al.(2015)
dve_1
0.833 0.868
dve
M03838_2.00
Drosophila melanogaster
TAATTWATKC

GMATWAATTA
SELEX
Nitta et al.(2015)
dve_2
0.833 0.868
dve
M03839_2.00
Drosophila melanogaster
YHATTATGYTAATKA

TMATTARCATAATDR
SELEX
Nitta et al.(2015)
dve_3
0.833 0.868
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
HHAL008908-PA Homeodomain 11 78
HHAL008908-PA Homeodomain 265 332

Links

Other Homeodomain family TFs
Other Halyomorpha halys TFs

63 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
RPRC004899 Rhodnius prolixus RPRC004899 I 0.853
PHUM502960 Pediculus humanus PHUM502960 I 0.846
TC001741 Tribolium castaneum TC001741 I 0.845
CLEC004759 Cimex lectularius CLEC004759 I 0.842
Hsal_07106--XP_001606248.1_NASVI Harpegnathos saltator Hsal_07106--XP_001606248.1_NASVI I 0.841
ACEP17090 Atta cephalotes ACEP17090 I 0.841
SINV11333 Solenopsis invicta SINV11333 I 0.841
Cflo_07225--XP_001606248.1_NASVI Camponotus floridanus Cflo_07225--XP_001606248.1_NASVI I 0.841
HMEL015950 Heliconius melpomene HMEL015950 I 0.837
KGM_06737 Danaus plexippus KGM_06737 I 0.837
MCINX008112 Melitaea cinxia MCINX008112 I 0.837
AATE017517 Anopheles atroparvus AATE017517 I 0.837
BGIBMGA002615 Bombyx mori BGIBMGA002615 I 0.837
GK20806 Drosophila willistoni FBgn0222802 I 0.836
AMIN007755 Anopheles minimus AMIN007755 I 0.835
AMEM004713 Anopheles merus AMEM004713 I 0.835
AMEC015188 Anopheles melas AMEC015188 I 0.835
LCUP002690 Lucilia cuprina LCUP002690 I 0.835
AQUA004750 Anopheles quadriannulatus AQUA004750 I 0.835
ASIS003438 Anopheles sinensis ASIS003438 I 0.835
PPAI002585 Phlebotomus papatasi PPAI002585 I 0.835
MDOA012801 Musca domestica MDOA012801 I 0.835
LLOJ007250 Lutzomyia longipalpis LLOJ007250 I 0.835
LDEC014136 Leptinotarsa decemlineata LDEC014136 I 0.835
AMAM001922 Anopheles maculatus AMAM001922 I 0.835
ACOM039410 Anopheles coluzzii ACOM039410 I 0.835
YQE_09198 Dendroctonus ponderosae YQE_09198 I 0.835
ACUA026318 Anopheles culicifacies ACUA026318 I 0.835
ADIR007339 Anopheles dirus ADIR007339 I 0.835
ACHR004661 Anopheles christyi ACHR004661 I 0.835
AFAF019299 Anopheles farauti AFAF019299 I 0.835
AALB004829 Anopheles albimanus AALB004829 I 0.835
AFUN004267 Anopheles funestus AFUN004267 I 0.835
AARA008518 Anopheles arabiensis AARA008518 I 0.835
AEPI005009 Anopheles epiroticus AEPI005009 I 0.835
CpipJ_CPIJ005190 Culex pipiens CpipJ_CPIJ005190 I 0.835
L798_03211 Zootermopsis nevadensis L798_03211 I 0.835
GH21453 Drosophila grimshawi FBgn0128915 I 0.835
GI19929 Drosophila mojavensis FBgn0142666 I 0.835
GL17532 Drosophila persimilis FBgn0155135 I 0.835
GJ15096 Drosophila virilis FBgn0202295 I 0.835
GF12619 Drosophila ananassae FBgn0089655 I 0.835
GA19138 Drosophila pseudoobscura FBgn0079135 I 0.835
ADAC003119 Anopheles darlingi ADAC003119 I 0.835
CPIJ005190 Culex quinquefasciatus CPIJ005190 I 0.835
dve Drosophila melanogaster FBgn0020307 D 0.833
GG22176 Drosophila erecta FBgn0114350 I 0.833
GM15897 Drosophila sechellia FBgn0170813 I 0.833
GE14170 Drosophila yakuba FBgn0231792 I 0.833
ISCW015706 Ixodes scapularis ISCW015706 I 0.831
ACYPI009254 Acyrthosiphon pisum ACYPI009254 I 0.831
NV13500 Nasonia vitripennis NV13500 I 0.830
SMAR004501 Strigamia maritima SMAR004501 I 0.827
tetur20g03290 Tetranychus urticae tetur20g03290 I 0.813
GK23597 Drosophila willistoni FBgn0225559 I 0.813
DAPPUDRAFT_302916 Daphnia pulex DAPPUDRAFT_302916 I 0.801
PHUM373730 Pediculus humanus PHUM373730 I 0.800
GK24109 Drosophila willistoni FBgn0226071 I 0.677
BGLB008208 Biomphalaria glabrata BGLB008208 I 0.656
LotgiG173809 Lottia gigantea LotgiG173809 I 0.645
CGI_10015221 Crassostrea gigas CGI_10015221 I 0.642
Ocbimv22009013m.g Octopus bimaculoides Ocbimv22009013m.g I 0.640
GB50892 Apis mellifera GB50892 I 0.630