D915_02578 (Fasciola hepatica)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00046 (Homeobox) IPR001356 D915_02578 T233417_2.00 WormBase:ParaSite (2015-Oct-22)

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Nkx3-1
M00170_2.00
Mus musculus
NDAAGTRBNN

NNVYACTTHN
PBM
Badis et al.(2009)
Nkx3-1_2923
0.710 0.784
Nkx3-1
M00420_2.00
Mus musculus
NNAAGTRBNN

NNVYACTTNN
PBM
Berger et al.(2008)
Nkx3-1_2923
0.710 0.784
NKX3-1
M05255_2.00
Homo sapiens
NNTAAGTGSN

NSCACTTANN
SELEX
Yin et al.(2017)
NKX3-1_eDBD_HT-SELEX
0.710 0.784
NKX3-1
M09154_2.00
Homo sapiens
NYDAAGTGBYWD

HWRVCACTTHRN
Misc
Kulakovskiy et al.(2013)
NKX31_HUMAN.H11MO.0.C
0.710 0.784
Nkx3-1
M09184_2.00
Mus musculus
NYDAAGTGBYWD

HWRVCACTTHRN
Misc
Kulakovskiy et al.(2013)
NKX31_MOUSE.H11MO.0.C
0.710 0.784
NKX3-1
M09559_2.00
Homo sapiens
BTRAGTRBYY

RRVYACTYAV
Misc
Heinz et al.(2010)
LNCaP-Nkx3.1_GSE28264
0.710 0.784
NKX3-1
M10729_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
P$GT1_Q6_01
0.710 0.784
NKX3-1
M10730_2.00
Homo sapiens
NWWTAAGTATWH

DWATACTTAWWN
Transfac
Matys et al.(2006)
V$NKX3A_01
0.710 0.784
NKX3-1
M10731_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NKX3A_Q3
0.710 0.784
NKX3-1
M05256_2.00
Homo sapiens
NNTAAGTGBN

NVCACTTANN
SELEX
Yin et al.(2017)
NKX3-1_eDBD_Methyl-HT-SELEX_1
0.710 0.784
NKX3-1
M05257_2.00
Homo sapiens
NTAAYSWB

VWSRTTAN
SELEX
Yin et al.(2017)
NKX3-1_eDBD_Methyl-HT-SELEX_2
0.710 0.784
Nkx3-2
M00506_2.00
Mus musculus
NNRAGDRNN

NNYHCTYNN
PBM
Berger et al.(2008)
Bapx1_2343
0.696 0.824
NKX3-2
M05012_2.00
Homo sapiens
NNTAAGTGSN

NSCACTTANN
SELEX
Yin et al.(2017)
NKX3-2_eDBD_HT-SELEX
0.696 0.824
NKX3-2
M09138_2.00
Homo sapiens
TTAAGTGBNH

DNVCACTTAA
Misc
Kulakovskiy et al.(2013)
NKX32_HUMAN.H11MO.0.C
0.696 0.824
Nkx3-2
M09212_2.00
Mus musculus
TTAAGTGBNH

DNVCACTTAA
Misc
Kulakovskiy et al.(2013)
NKX32_MOUSE.H11MO.0.B
0.696 0.824
NKX3-2
M10663_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NKX32_01
0.696 0.824
NKX3-2
M05013_2.00
Homo sapiens
NNTAAGTGBN

NVCACTTANN
SELEX
Yin et al.(2017)
NKX3-2_eDBD_Methyl-HT-SELEX_1
0.696 0.824
NKX3-2
M05014_2.00
Homo sapiens
NTAACGHB

VDCGTTAN
SELEX
Yin et al.(2017)
NKX3-2_eDBD_Methyl-HT-SELEX_2
0.696 0.824
bap
M00560_2.00
Drosophila melanogaster
NDAAGTRBNN

NNVYACTTHN
PBM
Busser et al.(2012a)
Bap
0.692 0.824
bap
M02119_2.00
Drosophila melanogaster
NYTAAGTRSNN

NNSYACTTARN
PBM
Weirauch et al.(2014)
pTH5945
0.692 0.824
bap
M03812_2.00
Drosophila melanogaster
NNTAAGTGBN

NVCACTTANN
SELEX
Nitta et al.(2015)
bap_1
0.692 0.824
bap
M06504_2.00
Drosophila melanogaster
TTAAGTR

YACTTAA
B1H
Mathelier et al.(2014)
MA0211.1
0.692 0.824
bap
M06287_2.00
Drosophila melanogaster
NBTTAAGTRN

NYACTTAAVN
B1H
Zhu et al.(2011)
Bap_Cell_FBgn0004862
0.692 0.824
bap
M06288_2.00
Drosophila melanogaster
NYTAAKTR

YAMTTARN
B1H
Zhu et al.(2011)
Bap_SOLEXA_FBgn0004862
0.692 0.824
ENSCING00000007395
M02076_2.00
Ciona intestinalis
NNNDWNWR

YWNWHNNN
PBM
Weirauch et al.(2014)
pTH5922
0.688 0.647
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
D915_02578 Homeodomain 156 206

Links

Other Homeodomain family TFs
Other Fasciola hepatica TFs

191 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
Nkx3-2 Mus musculus ENSMUSG00000049691 D 0.696
bap Drosophila melanogaster FBgn0004862 D 0.692
ENSCING00000007395 Ciona intestinalis ENSCING00000007395 D 0.688
NKX3-2 Homo sapiens ENSG00000109705 D 0.696
NKX3-1 Homo sapiens ENSG00000167034 D 0.710
Nkx3-1 Mus musculus ENSMUSG00000022061 D 0.710
KGM_11246 Danaus plexippus KGM_11246 I 0.693
tetur04g08350 Tetranychus urticae tetur04g08350 I 0.697
ISCW014989 Ixodes scapularis ISCW014989 I 0.693
HMEL006181 Heliconius melpomene HMEL006181 I 0.693
HelroG148616 Helobdella robusta HelroG148616 I 0.695
GB47401 Apis mellifera GB47401 I 0.689
GE25732 Drosophila yakuba FBgn0242790 I 0.692
LotgiG60615 Lottia gigantea LotgiG60615 I 0.680
MCINX004875 Melitaea cinxia MCINX004875 I 0.693
TC012743 Tribolium castaneum TC012743 I 0.695
SPU_013047 Strongylocentrotus purpuratus SPU_013047 I 0.695
Smp_140730 Schistosoma mansoni Smp_140730 I 0.740
SMAR005030 Strigamia maritima SMAR005030 I 0.696
SINV22315 Solenopsis invicta SINV22315 I 0.689
RPRC001122 Rhodnius prolixus RPRC001122 I 0.694
PHUM439840 Pediculus humanus PHUM439840 I 0.694
NV25828 Nasonia vitripennis NV25828 I 0.689
NEMVEDRAFT_v1g208034 Nematostella vectensis NEMVEDRAFT_v1g208034 I 0.690
MESCA006298 Megaselia scalaris MESCA006298 I 0.695
GK14503 Drosophila willistoni FBgn0216509 I 0.692
GJ14311 Drosophila virilis FBgn0201526 I 0.692
ENSTTRG00000003623 Tursiops truncatus ENSTTRG00000003623 I 0.696
ENSTSYG00000007109 Tarsius syrichta ENSTSYG00000007109 I 0.710
nkx3.2 Takifugu rubripes ENSTRUG00000014438 I 0.696
nkx3.2 Tetraodon nigroviridis ENSTNIG00000015732 I 0.696
ENSTBEG00000002319 Tupaia belangeri ENSTBEG00000002319 I 0.710
ENSSTOG00000021803 Ictidomys tridecemlineatus ENSSTOG00000021803 I 0.696
ENSSSCG00000028216 Sus scrofa ENSSSCG00000028216 I 0.710
ENSSSCG00000024594 Sus scrofa ENSSSCG00000024594 I 0.696
ENSSHAG00000015475 Sarcophilus harrisii ENSSHAG00000015475 I 0.710
ENSSARG00000001895 Sorex araneus ENSSARG00000001895 I 0.710
NKX3-1 Vicugna pacos ENSVPAG00000004503 I 0.710
ENSXMAG00000016282 Xiphophorus maculatus ENSXMAG00000016282 I 0.696
GL27337 Drosophila persimilis FBgn0164918 I 0.692
GI21951 Drosophila mojavensis FBgn0144680 I 0.692
GH22032 Drosophila grimshawi FBgn0129493 I 0.692
GG24598 Drosophila erecta FBgn0116730 I 0.692
GF18600 Drosophila ananassae FBgn0095618 I 0.692
GA20672 Drosophila pseudoobscura FBgn0080666 I 0.692
bap Drosophila sechellia FBgn0067536 I 0.692
bap Drosophila simulans FBgn0067504 I 0.692
ENSXMAG00000020262 Xiphophorus maculatus ENSXMAG00000020262 I 0.700
ENSXMAG00000020095 Xiphophorus maculatus ENSXMAG00000020095 I 0.693
Nkx3-2 Rattus norvegicus ENSRNOG00000060782 I 0.696
YQE_10102 Dendroctonus ponderosae YQE_10102 I 0.695
TCLT_0000478201 Thelazia callipaeda TCLT_0000478201 I 0.613
AMEM005009 Anopheles merus AMEM005009 I 0.709
AMEC017317 Anopheles melas AMEC017317 I 0.709
AMAM011860 Anopheles maculatus AMAM011860 I 0.709
AFUN008966 Anopheles funestus AFUN008966 I 0.709
AFAF013479 Anopheles farauti AFAF013479 I 0.709
AEPI001627 Anopheles epiroticus AEPI001627 I 0.709
ADIR005347 Anopheles dirus ADIR005347 I 0.709
ACUA019412 Anopheles culicifacies ACUA019412 I 0.709
ACOM028774 Anopheles coluzzii ACOM028774 I 0.709
AMIN004031 Anopheles minimus AMIN004031 I 0.709
AQUA001538 Anopheles quadriannulatus AQUA001538 I 0.709
ASIS007650 Anopheles sinensis ASIS007650 I 0.709
SMTD_0000549701 Schistosoma mattheei SMTD_0000549701 I 0.740
SMRZ_0000016501 Schistosoma margrebowiei SMRZ_0000016501 I 0.740
PXEA_0003190801 Protopolystoma xenopodis PXEA_0003190801 I 0.735
csin109461 Clonorchis sinensis csin109461 I 0.741
A_02450 Schistosoma haematobium A_02450 I 0.740
PPAI010327 Phlebotomus papatasi PPAI010327 I 0.697
MDOA010758 Musca domestica MDOA010758 I 0.697
BGLB010692 Biomphalaria glabrata BGLB010692 I 0.702
ASTEI07437 Anopheles stephensi ASTEI07437 I 0.709
ACHR006588 Anopheles christyi ACHR006588 I 0.709
AATE016309 Anopheles atroparvus AATE016309 I 0.709
AARA010121 Anopheles arabiensis AARA010121 I 0.709
Ocbimv22026957m.g Octopus bimaculoides Ocbimv22026957m.g I 0.695
estExt_fgenesh2_pg.C_1430013 Branchiostoma floridae estExt_fgenesh2_pg.C_1430013 I 0.695
Pvit_15821 Pogona vitticeps Pvit_15821 I 0.696
Myotis_brandtii_NKX3_10014306 Myotis brandtii Myotis_brandtii_NKX3_10014306 I 0.710
Hsal_06436--XP_001120208.1_APIME Harpegnathos saltator Hsal_06436--XP_001120208.1_APIME I 0.689
ENSP00000371875 Macaca fascicularis ENSP00000371875 I 0.680
ENSP00000370253 Macaca fascicularis ENSP00000370253 I 0.710
ENSBTAP00000001615-D1 Bos grunniens ENSBTAP00000001615-D1 I 0.710
Alligator_sinensis_CCG000534.1 Alligator sinensis Alligator_sinensis_CCG000534.1 I 0.696
Sakowv30040088m.g Saccoglossus kowalevskii Sakowv30040088m.g I 0.696
CLEC002956 Cimex lectularius CLEC002956 I 0.693
LCUP000733 Lucilia cuprina LCUP000733 I 0.697
XP_002932598 Xenopus tropicalis XP_002932598 I 0.698
nkx3-2.S Xenopus laevis XB-GENE-876836 I 0.696
nkx3-2 Xenopus tropicalis XB-GENE-876834 I 0.696
nkx3-3.S Xenopus laevis XB-GENE-865322 I 0.693
nkx3-1.S Xenopus laevis XB-GENE-6252708 I 0.698
nkx3-3 Xenopus tropicalis XB-GENE-479908 I 0.693
nkx3-1.L Xenopus laevis XB-GENE-479031 I 0.698
SMU15003549 Schmidtea mediterranea SMU15003549 I 0.722
LDEC009723 Leptinotarsa decemlineata LDEC009723 I 0.695
Aan_R009530 Calypte anna Aan_R009530 I 0.601
ENSLACG00000003608 Latimeria chalumnae ENSLACG00000003608 I 0.696
NKX3-1 Dasypus novemcinctus ENSDNOG00000044451 I 0.710
NKX3-2 Dasypus novemcinctus ENSDNOG00000043074 I 0.696
nkx3-1 Danio rerio ENSDARG00000078280 I 0.703
nkx3.3 Danio rerio ENSDARG00000069327 I 0.694
nkx3.2 Danio rerio ENSDARG00000037639 I 0.696
ENSCSAG00000016338 Chlorocebus sabaeus ENSCSAG00000016338 I 0.696
ENSCSAG00000016229 Chlorocebus sabaeus ENSCSAG00000016229 I 0.710
ENSCPOG00000010557 Cavia porcellus ENSCPOG00000010557 I 0.710
NKX3-2 Cavia porcellus ENSCPOG00000005449 I 0.696
ENSECAG00000001509 Equus caballus ENSECAG00000001509 I 0.710
NKX3-1 Erinaceus europaeus ENSEEUG00000001113 I 0.710
ENSEEUG00000012691 Erinaceus europaeus ENSEEUG00000012691 I 0.696
ENSGMOG00000018725 Gadus morhua ENSGMOG00000018725 I 0.696
ENSGMOG00000005518 Gadus morhua ENSGMOG00000005518 I 0.701
NKX3-1 Gorilla gorilla ENSGGOG00000014369 I 0.710
NKX3-2 Gorilla gorilla ENSGGOG00000008589 I 0.696
nkx3.2 Gasterosteus aculeatus ENSGACG00000016378 I 0.696
nkx3-1 Gasterosteus aculeatus ENSGACG00000010776 I 0.713
nkx3.3 Gasterosteus aculeatus ENSGACG00000007573 I 0.693
ENSFALG00000011121 Ficedula albicollis ENSFALG00000011121 I 0.698
NKX3-1 Echinops telfairi ENSETEG00000018790 I 0.698
NKX3-1 Callithrix jacchus ENSCJAG00000020092 I 0.710
NKX3-2 Callithrix jacchus ENSCJAG00000012159 I 0.696
CPIJ004109 Culex quinquefasciatus CPIJ004109 I 0.697
CGI_10023919 Crassostrea gigas CGI_10023919 I 0.695
CapteG79432 Capitella teleta CapteG79432 I 0.704
BGIBMGA010706 Bombyx mori BGIBMGA010706 I 0.693
AGAP003671 Anopheles gambiae AGAP003671 I 0.709
ADAC003526 Anopheles darlingi ADAC003526 I 0.709
ACYPI002893 Acyrthosiphon pisum ACYPI002893 I 0.696
ACEP23863 Atta cephalotes ACEP23863 I 0.689
AAEL006597 Aedes aegypti AAEL006597 I 0.697
ENSACAG00000026683 Anolis carolinensis ENSACAG00000026683 I 0.698
ENSAMEG00000002866 Ailuropoda melanoleuca ENSAMEG00000002866 I 0.710
ENSAMEG00000009342 Ailuropoda melanoleuca ENSAMEG00000009342 I 0.696
ENSCHOG00000011132 Choloepus hoffmanni ENSCHOG00000011132 I 0.710
NKX3-2 Canis familiaris ENSCAFG00000015412 I 0.696
ENSCAFG00000009107 Canis familiaris ENSCAFG00000009107 I 0.710
NKX3-2 Bos taurus ENSBTAG00000010896 I 0.696
NKX3-1 Bos taurus ENSBTAG00000001221 I 0.710
ENSAPLG00000014690 Anas platyrhynchos ENSAPLG00000014690 I 0.710
ENSAMXG00000024837 Astyanax mexicanus ENSAMXG00000024837 I 0.700
ENSAMXG00000003840 Astyanax mexicanus ENSAMXG00000003840 I 0.696
ENSAMXG00000002250 Astyanax mexicanus ENSAMXG00000002250 I 0.693
CpipJ_CPIJ004109 Culex pipiens CpipJ_CPIJ004109 I 0.697
ENSLACG00000012763 Latimeria chalumnae ENSLACG00000012763 I 0.694
Nkx3-1 Rattus norvegicus ENSRNOG00000015477 I 0.710
NKX3-2 Procavia capensis ENSPCAG00000013077 I 0.696
ENSPANG00000021310 Papio anubis ENSPANG00000021310 I 0.696
ENSPANG00000004934 Papio anubis ENSPANG00000004934 I 0.710
nkx3-1 Oryzias latipes ENSORLG00000010925 I 0.701
ENSORLG00000007716 Oryzias latipes ENSORLG00000007716 I 0.693
nkx3.2 Oryzias latipes ENSORLG00000000593 I 0.696
ENSOPRG00000005452 Ochotona princeps ENSOPRG00000005452 I 0.696
NKX3-1 Ochotona princeps ENSOPRG00000003179 I 0.710
ENSONIG00000011762 Oreochromis niloticus ENSONIG00000011762 I 0.701
ENSPCAG00000016644 Procavia capensis ENSPCAG00000016644 I 0.710
ENSPFOG00000002882 Poecilia formosa ENSPFOG00000002882 I 0.696
ENSPFOG00000009654 Poecilia formosa ENSPFOG00000009654 I 0.700
NKX3-1 Pteropus vampyrus ENSPVAG00000005378 I 0.710
NKX3-2 Pteropus vampyrus ENSPVAG00000002830 I 0.696
ENSPTRG00000031253 Pan troglodytes ENSPTRG00000031253 I 0.696
NKX3-1 Pan troglodytes ENSPTRG00000020081 I 0.710
ENSPSIG00000017342 Pelodiscus sinensis ENSPSIG00000017342 I 0.710
ENSPSIG00000012169 Pelodiscus sinensis ENSPSIG00000012169 I 0.696
ENSPPYG00000018442 Pongo abelii ENSPPYG00000018442 I 0.710
ENSPPYG00000014611 Pongo abelii ENSPPYG00000014611 I 0.696
ENSPFOG00000020885 Poecilia formosa ENSPFOG00000020885 I 0.693
ENSONIG00000002379 Oreochromis niloticus ENSONIG00000002379 I 0.696
NKX3-2 Otolemur garnettii ENSOGAG00000015615 I 0.696
NKX3-1 Macaca mulatta ENSMMUG00000009796 I 0.710
NKX3-2 Myotis lucifugus ENSMLUG00000008362 I 0.696
NKX3-1 Myotis lucifugus ENSMLUG00000006118 I 0.710
NKX3-1 Microcebus murinus ENSMICG00000011189 I 0.710
ENSMICG00000000190 Microcebus murinus ENSMICG00000000190 I 0.696
ENSLOCG00000015015 Lepisosteus oculatus ENSLOCG00000015015 I 0.700
ENSLOCG00000009892 Lepisosteus oculatus ENSLOCG00000009892 I 0.696
ENSLOCG00000009031 Lepisosteus oculatus ENSLOCG00000009031 I 0.693
NKX3-2 Loxodonta africana ENSLAFG00000031404 I 0.696
ENSMMUG00000022026 Macaca mulatta ENSMMUG00000022026 I 0.696
NKX3-1 Monodelphis domestica ENSMODG00000016789 I 0.710
NKX3-2 Monodelphis domestica ENSMODG00000024753 I 0.696
NKX3-1 Otolemur garnettii ENSOGAG00000001303 I 0.710
NKX3-2 Oryctolagus cuniculus ENSOCUG00000009039 I 0.696
NKX3-1 Oryctolagus cuniculus ENSOCUG00000004294 I 0.710
ENSOARG00000010071 Ovis aries ENSOARG00000010071 I 0.710
NKX3-1 Ornithorhynchus anatinus ENSOANG00000008027 I 0.710
ENSNLEG00000016256 Nomascus leucogenys ENSNLEG00000016256 I 0.696
ENSNLEG00000015968 Nomascus leucogenys ENSNLEG00000015968 I 0.710
ENSMPUG00000003418 Mustela putorius furo ENSMPUG00000003418 I 0.710
ENSMPUG00000000476 Mustela putorius furo ENSMPUG00000000476 I 0.696
NKX3-1 Loxodonta africana ENSLAFG00000008941 I 0.710