snap_masked-nMf.1.1.scaf16485-processed-gene-0.2 (Meloidogyne floridensis)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00046 (Homeobox) IPR001356 snap_masked-nMf.1.1.scaf16485-processed-gene-0.2 T236240_2.00 WormBase:ParaSite (2015-Oct-22)
NCBI Gene Info:
This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to transforming growth factor (TGF)-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The protein acts as a tumor suppressor and inhibits epithelial cell proliferation. It may also have an inhibitory effect on tumors by reducing angiogenesis and increasng blood vessel hyperpermeability. The encoded protein is a crucial component of the bone morphogenetic protein signaling pathway. The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. [provided by RefSeq, Aug 2017]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
snap_masked-nMf.1.1.scaf16485-processed-gene-0.2-mRNA-1 Homeodomain 5 63

Links

Other Homeodomain family TFs
Other Meloidogyne floridensis TFs

50 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ANCCAN_27245 Ancylostoma caninum ANCCAN_27245 N 0.769
NEMVEDRAFT_v1g48861 Nematostella vectensis NEMVEDRAFT_v1g48861 N 0.671
ENSPANG00000010570 Papio anubis ENSPANG00000010570 N 0.659
OTX2 Myotis lucifugus ENSMLUG00000022591 I 0.659
LEUTX Pan troglodytes ENSPTRG00000033892 N 0.659
ENSCSAG00000003788 Chlorocebus sabaeus ENSCSAG00000003788 N 0.659
LEUTX Homo sapiens ENSG00000213921 N 0.659
WUBG_02624 Wuchereria bancrofti WUBG_02624 N 0.659
WUBG_02192 Wuchereria bancrofti WUBG_02192 N 0.639
ISCW006446 Ixodes scapularis ISCW006446 N 0.639
ENSSTOG00000026735 Ictidomys tridecemlineatus ENSSTOG00000026735 N 0.635
GK22279 Drosophila willistoni FBgn0224264 N 0.633
Hba_17538 Heterorhabditis bacteriophora Hba_17538 N 0.631
Traes_6BS_96BBFCC97 Triticum aestivum Traes_6BS_96BBFCC97 N 0.627
Sjc_0128760 Schistosoma japonicum Sjc_0128760 N 0.627
XP_002164986.1 Hydra magnipapillata XP_002164986.1 N 0.624
CBG15039 Caenorhabditis briggsae CBG15039 N 0.614
ANCCEY_11895 Ancylostoma ceylanicum ANCCEY_11895 N 0.614
SMTD_0001972301 Schistosoma mattheei SMTD_0001972301 N 0.613
ENSCJAG00000011381 Callithrix jacchus ENSCJAG00000011381 N 0.612
GB50469 Apis mellifera GB50469 N 0.612
TPRX1 Homo sapiens ENSG00000178928 I 0.612
AEPI010431 Anopheles epiroticus AEPI010431 N 0.606
AALB006874 Anopheles albimanus AALB006874 N 0.606
TTRE_0000079401 Trichuris trichiura TTRE_0000079401 N 0.606
ASIS015315 Anopheles sinensis ASIS015315 N 0.606
TELCIR_18721 Teladorsagia circumcincta TELCIR_18721 N 0.606
snap_masked-nMf.1.1.scaf19847-processed-gene-0.1 Meloidogyne floridensis snap_masked-nMf.1.1.scaf19847-processed-gene-0.1 N 0.606
GPLIN_000181000 Globodera pallida GPLIN_000181000 N 0.606
ANCCEY_04348 Ancylostoma ceylanicum ANCCEY_04348 N 0.606
OESDEN_16215 Oesophagostomum dentatum OESDEN_16215 N 0.606
LDEC016519 Leptinotarsa decemlineata LDEC016519 N 0.606
ACEP26305 Atta cephalotes ACEP26305 N 0.606
Alligator_sinensis_CCG004399.1 Alligator sinensis Alligator_sinensis_CCG004399.1 N 0.606
Otx2 Mus musculus ENSMUSG00000021848 D 0.606
EFV55958 Trichinella spiralis EFV55958 N 0.606
CJA11256 Caenorhabditis japonica CJA11256 N 0.606
DMBX1 Monodelphis domestica ENSMODG00000001963 N 0.606
OTX2 Choloepus hoffmanni ENSCHOG00000013827 I 0.606
pitx1 Gasterosteus aculeatus ENSGACG00000016483 I 0.606
ENSLAFG00000000420 Loxodonta africana ENSLAFG00000000420 N 0.606
HMEL015659 Heliconius melpomene HMEL015659 I 0.606
CGI_10007832 Crassostrea gigas CGI_10007832 N 0.606
Hsal_07660--XP_394161.1_APIME Harpegnathos saltator Hsal_07660--XP_394161.1_APIME I 0.606
Ocbimv22035611m.g Octopus bimaculoides Ocbimv22035611m.g I 0.606
Cmyd_10017639 Chelonia mydas Cmyd_10017639 I 0.606
ENSCSAG00000014537 Chlorocebus sabaeus ENSCSAG00000014537 I 0.606
unc-30 Caenorhabditis elegans WBGene00006766 I 0.606
YQE_12574 Dendroctonus ponderosae YQE_12574 N 0.606
CLEC006124 Cimex lectularius CLEC006124 N 0.606