pax6a (Danio rerio)
Homeodomain,Paired box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00292 (PAX) 		IPR001356
IPR001523 		ENSDARG00000103379 T237311_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
VAX1
M03168_2.00 		Homo sapiens
YTAATKAN
NTMATTAR		 SELEX
Jolma et al.(2013)
VAX1_1 		0.687 0.450
pax2b
M02425_2.00 		Danio rerio
HVNYSRNSCR
YGSNYSRNBD		 PBM
Weirauch et al.(2014)
pTH8679 		0.776 0.776
PAX6
M00342_2.00 		Homo sapiens
NNNRCDMATTANNN
NNNTAATKHGYNNN		 PBM
Barrera et al.(2016)
PAX6_REF 		0.989 0.989
Pax6
M00540_2.00 		Mus musculus
CBAATTAA
TTAATTVG		 PBM
Berger et al.(2008)
Pax6_3838 		0.995 0.995
VAX1
M05182_2.00 		Homo sapiens
BTAATTRN
NYAATTAV		 SELEX
Yin et al.(2017)
VAX1_eDBD_HT-SELEX 		0.687 0.450
Pax5B
M01301_2.00 		Gallus gallus
NSNDTNNNN
NNNNAHNSN		 PBM
Lambert et al.(2019)
pTH9781 		0.776 0.776
PAX6
M03291_2.00 		Homo sapiens
DTWYACGCWTGANTGMDYH
DRHKCANTCAWGCGTRWAH		 SELEX
Jolma et al.(2013)
PAX6_1 		0.995 0.995
VAX1
M05183_2.00 		Homo sapiens
BTMATKRN
NYMATKAV		 SELEX
Yin et al.(2017)
VAX1_eDBD_Methyl-HT-SELEX 		0.687 0.450
pax2
M02428_2.00 		Xenopus tropicalis
NNNRNBCRNN
NNYGVNYNNN		 PBM
Weirauch et al.(2014)
pTH8556 		0.776 0.776
PAX6
M05412_2.00 		Homo sapiens
NYACGCHYSRNYRMNYN
NRNKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_eDBD_HT-SELEX 		0.989 0.989
VSX1
M03087_2.00 		Homo sapiens
YTAATTAN
NTAATTAR		 SELEX
Jolma et al.(2013)
VSX1_1 		0.680 0.600
PAX5
M03443_2.00 		Homo sapiens
RNBYANYSAWSCGTRACN
NGTYACGSWTSRNTRVNY		 SELEX
Jolma et al.(2013)
PAX5_1 		0.776 0.776
PAX5
M08160_2.00 		Homo sapiens
RDGCGTGACCNN
NNGGTCACGCHY		 ChIP-seq
Mathelier et al.(2014)
MA0014.3 		0.829 0.829
PAX6
M05414_2.00 		Homo sapiens
NYRCGCNYSRNYRVNYN
NRNBYRNYSRNGCGYRN		 SELEX
Yin et al.(2017)
PAX6_FL_HT-SELEX 		0.989 0.989
VSX1
M03088_2.00 		Homo sapiens
NNYAATTRRBN
NVYYAATTRNN		 SELEX
Jolma et al.(2013)
VSX1_2 		0.680 0.600
VSX1
M04941_2.00 		Homo sapiens
YYAATTRN
NYAATTRR		 SELEX
Yin et al.(2017)
VSX1_eDBD_HT-SELEX 		0.680 0.590
PAX5
M07995_2.00 		Homo sapiens
BCAVYSRDSCRKRRC
GYYMYGSHYSRBTGV		 ChIP-seq
Gerstein et al.(2012)
GM12878_PAX5C20_HudsonAlpha 		0.829 0.829
PAX6
M02689_2.00 		Homo sapiens
TTYACGCWTSANTK
MANTSAWGCGTRAA		 SELEX
Mathelier et al.(2014)
MA0069.1 		0.989 0.989
PAX5
M07996_2.00 		Homo sapiens
BCASYSRDSCRTRAC
GTYAYGSHYSRSTGV		 ChIP-seq
Gerstein et al.(2012)
GM12878_PAX5N19_HudsonAlpha 		0.776 0.776
VSX1
M04944_2.00 		Homo sapiens
NTAATTRS
SYAATTAN		 SELEX
Yin et al.(2017)
VSX1_FL_HT-SELEX 		0.680 0.590
PAX6
M09216_2.00 		Homo sapiens
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_HUMAN.H11MO.0.C 		0.989 0.989
VSX1
M05869_2.00 		Homo sapiens
DGCTAATTAN
NTAATTAGCH		 SMiLE-seq
Isakova et al.(2017)
VSX1 		0.680 0.600
PAX5
M07997_2.00 		Homo sapiens
CASYSRDSCRKRACN
NGTYMYGSHYSRSTG		 ChIP-seq
Gerstein et al.(2012)
GM12891_PAX5C20_HudsonAlpha 		0.776 0.776
Pax6
M09217_2.00 		Mus musculus
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_MOUSE.H11MO.0.C 		0.989 0.989
VSX1
M04942_2.00 		Homo sapiens
NTAAYGMN
NKCRTTAN		 SELEX
Yin et al.(2017)
VSX1_eDBD_Methyl-HT-SELEX_1 		0.680 0.600
PAX5
M07998_2.00 		Homo sapiens
BCASYSRDSCGKRRC
GYYMCGSHYSRSTGV		 ChIP-seq
Gerstein et al.(2012)
GM12892_PAX5C20_HudsonAlpha 		0.776 0.776
PAX6
M10806_2.00 		Homo sapiens
NHNNTTYACGCWTSANTKVHH
DDBMANTSAWGCGTRAANNDN		 Transfac
Matys et al.(2006)
V$PAX6_01 		0.989 0.989
PAX6
M10807_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX6_Q2 		0.995 0.995
VSX1
M04943_2.00 		Homo sapiens
YYAATTRN
NYAATTRR		 SELEX
Yin et al.(2017)
VSX1_eDBD_Methyl-HT-SELEX_2 		0.680 0.600
PAX5
M08227_2.00 		Homo sapiens
BCANYSRDGCGTRAM
KTYACGCHYSRNTGV		 ChIP-seq
Contrino et al.(2012)
Mv108 		0.776 0.776
PAX6
M05413_2.00 		Homo sapiens
DYRCGCWTSRNYRMNYN
NRNKYRNYSAWGCGYRH		 SELEX
Yin et al.(2017)
PAX6_eDBD_Methyl-HT-SELEX 		0.995 0.995
VSX1
M04945_2.00 		Homo sapiens
NTAATTRG
CYAATTAN		 SELEX
Yin et al.(2017)
VSX1_FL_Methyl-HT-SELEX_1 		0.680 0.600
PAX5
M08228_2.00 		Homo sapiens
AGCGTGRCYG
CRGYCACGCT		 ChIP-seq
Contrino et al.(2012)
Mv109 		0.776 0.776
PAX6
M05415_2.00 		Homo sapiens
NYACGCHYSRNYRMHYN
NRDKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_FL_Methyl-HT-SELEX 		0.989 0.989
VSX1
M04946_2.00 		Homo sapiens
NTAAYGAN
NTCRTTAN		 SELEX
Yin et al.(2017)
VSX1_FL_Methyl-HT-SELEX_2 		0.680 0.600
PAX5
M09341_2.00 		Homo sapiens
SNVDGNKCARCVRAGCRDGAC
GTCHYGCTYBGYTGMNCHBNS		 Misc
Kulakovskiy et al.(2013)
PAX5_HUMAN.H11MO.0.A 		0.776 0.776
Pax5
M09342_2.00 		Mus musculus
VDRNBCAVYVRDSCRKRRM
KYYMYGSHYBRBTGVNYHB		 Misc
Kulakovskiy et al.(2013)
PAX5_MOUSE.H11MO.0.A 		0.829 0.829
PAX6
M00335_2.00 		Homo sapiens
BRNNNNNN
NNNNNNYV		 PBM
Barrera et al.(2016)
PAX6_A79E 		0.984 0.984
PAX5
M09622_2.00 		Homo sapiens
BCASYSRDSCRTGRMN
NKYCAYGSHYSRSTGV		 Misc
Heinz et al.(2010)
GM12878-PAX5_GSE32465_1 		0.829 0.829
PAX6
M00336_2.00 		Homo sapiens
RTGCACAC
GTGTGCAY		 PBM
Barrera et al.(2016)
PAX6_F258S 		0.984 0.984
PAX5
M09623_2.00 		Homo sapiens
BCABNVRSCGTGAC
GTCACGSYBNVTGV		 Misc
Heinz et al.(2010)
GM12878-PAX5_GSE32465_2 		0.776 0.776
PAX6
M00337_2.00 		Homo sapiens
NMTAATTANNN
NNNTAATTAKN		 PBM
Barrera et al.(2016)
PAX6_P118R 		0.984 0.984
PAX5
M11208_2.00 		Homo sapiens
BCNNNRNKCANBGNWGNRKRGMSRSHNB
VNDSYSKCYMYNCWNCVNTGMNYNNNGV		 Transfac
Matys et al.(2006)
V$PAX5_01 		0.776 0.776
PAX6
M00338_2.00 		Homo sapiens
WSGVRVDR
YHBYBCSW		 PBM
Barrera et al.(2016)
PAX6_P68S 		0.984 0.984
PAX5
M11209_2.00 		Homo sapiens
VRHVDGDNDBBTNRAGCGKRACVRYNVH
DBNRYBGTYMCGCTYNAVVHNHCHBDYB		 Transfac
Matys et al.(2006)
V$PAX5_02 		0.776 0.776
PAX6
M00339_2.00 		Homo sapiens
NNNNSGKVGGHNN
NNDCCBMCSNNNN		 PBM
Barrera et al.(2016)
PAX6_R128C 		0.984 0.984
PAX6
M00340_2.00 		Homo sapiens
NNNNNRN
NYNNNNN		 PBM
Barrera et al.(2016)
PAX6_R242T 		0.989 0.989
PAX5
M11210_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX5_06 		0.776 0.776
PAX6
M00341_2.00 		Homo sapiens
BTSCCCSGSC
GSCSGGGSAV		 PBM
Barrera et al.(2016)
PAX6_R26G 		0.989 0.989
PAX5
M11211_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX5_07 		0.776 0.776
PAX6
M00343_2.00 		Homo sapiens
NNNNCCCVKCNBN
NVNGMBGGGNNNN		 PBM
Barrera et al.(2016)
PAX6_S119R 		0.984 0.984
PAX5
M11212_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX5_Q6 		0.776 0.776
sv
M01302_2.00 		Drosophila melanogaster
NNNSCRBRDM
KHYVYGSNNN		 PBM
Lambert et al.(2019)
pTH9773 		0.786 0.786
PAX6
M00344_2.00 		Homo sapiens
NNMSASGBYNNN
NNNRVCSTSKNN		 PBM
Barrera et al.(2016)
PAX6_V126D 		0.984 0.984
PAX8
M05685_2.00 		Homo sapiens
NRNBYRNYSRWGCGTGACSN
NSGTCACGCWYSRNYRVNYN		 SELEX
Yin et al.(2017)
PAX8_FL_HT-SELEX 		0.750 0.750
sv
M03949_2.00 		Drosophila melanogaster
NBCRNYSAWGCGTGACS
SGTCACGCWTSRNYGVN		 SELEX
Nitta et al.(2015)
sv_1 		0.786 0.786
ey
M03896_2.00 		Drosophila melanogaster
CKAATTAD
HTAATTMG		 SELEX
Nitta et al.(2015)
ey_1 		0.934 0.934
Pax8
M09624_2.00 		Rattus norvegicus
BCAGBCADSCRKGVM
KBCMYGSHTGVCTGV		 Misc
Heinz et al.(2010)
Thyroid-Pax8_GSE26938 		0.750 0.750
PAX8
M11205_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX8_01 		0.750 0.750
ey
M03897_2.00 		Drosophila melanogaster
HTAATCKMATTAD
HTAATKMGATTAD		 SELEX
Nitta et al.(2015)
ey_2 		0.934 0.934
PAX8
M11206_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX8_B 		0.750 0.750
sv
M06438_2.00 		Drosophila melanogaster
RNYSRDSCGTRACNN
NNGTYACGSHYSRNY		 B1H
Zhu et al.(2011)
sv_SOLEXA_5_FBgn0005561 		0.786 0.786
ey
M03898_2.00 		Drosophila melanogaster
WAAYYRRTTN
NAAYYRRTTW		 SELEX
Nitta et al.(2015)
ey_3 		0.934 0.934
PAX8
M05686_2.00 		Homo sapiens
NRNBCRNTSAWSCGYGACNN
NNGTCRCGSWTSANYGVNYN		 SELEX
Yin et al.(2017)
PAX8_FL_Methyl-HT-SELEX 		0.750 0.750
toy
M03899_2.00 		Drosophila melanogaster
TTYACGCWTGASTGMACAN
NTGTKCASTCAWGCGTRAA		 SELEX
Nitta et al.(2015)
toy_1 		0.912 0.912
toy
M03900_2.00 		Drosophila melanogaster
NTYACGCWTSAVTGMRCNN
NNGYKCABTSAWGCGTRAN		 SELEX
Nitta et al.(2015)
toy_2 		0.907 0.907
toy
M03901_2.00 		Drosophila melanogaster
VATTANBHAYGSWYSRN
NYSRWSCRTDVNTAATB		 SELEX
Nitta et al.(2015)
toy_3 		0.907 0.907
Poxn
M03946_2.00 		Drosophila melanogaster
DGCGTGACSGTCACGSY
RSCGTGACSGTCACGCH		 SELEX
Nitta et al.(2015)
Poxn_1 		0.757 0.757
Poxm
M03944_2.00 		Drosophila melanogaster
CAVTCAWGCGTGACR
YGTCACGCWTGABTG		 SELEX
Nitta et al.(2015)
Poxm_1 		0.707 0.707
Poxn
M03947_2.00 		Drosophila melanogaster
RSCGKGACSGTTMCGSW
WSCGKAACSGTCMCGSY		 SELEX
Nitta et al.(2015)
Poxn_2 		0.757 0.757
Poxm
M03945_2.00 		Drosophila melanogaster
NYSAWGCRTRACS
SGTYAYGCWTSRN		 SELEX
Nitta et al.(2015)
Poxm_2 		0.707 0.707
Poxm
M06436_2.00 		Drosophila melanogaster
NNNNNNMVNHNRNSCRTGA
TCAYGSNYNDNBKNNNNNN		 B1H
Zhu et al.(2011)
Poxm_SOLEXA_5_FBgn0003129 		0.707 0.707
Poxn
M03948_2.00 		Drosophila melanogaster
NCGTTCCGGAACGD
HCGTTCCGGAACGN		 SELEX
Nitta et al.(2015)
Poxn_3 		0.757 0.757
Poxn
M06437_2.00 		Drosophila melanogaster
RSCGTGACG
CGTCACGSY		 B1H
Zhu et al.(2011)
Poxn_SOLEXA_5_FBgn0003130 		0.757 0.757
PAX7
M00346_2.00 		Homo sapiens
NGTYAYGSHN
NDSCRTRACN		 PBM
Barrera et al.(2016)
PAX7_REF 		0.743 0.743
pax-2
M00706_2.00 		Caenorhabditis elegans
RMSCRTRACS
SGTYAYGSKY		 PBM
Narasimhan et al.(2015)
pTH10794 		0.743 0.743
PAX7
M00345_2.00 		Homo sapiens
NSGTCACGSN
NSCGTGACSN		 PBM
Barrera et al.(2016)
PAX7_P112L 		0.743 0.743
egl-38
M02426_2.00 		Caenorhabditis elegans
ACCGTGAYCAC
GTGRTCACGGT		 PBM
Weirauch et al.(2014)
pTH8981 		0.729 0.729
PAX1
M03442_2.00 		Homo sapiens
DBCANTSAWGCGTGACS
SGTCACGCWTSANTGVH		 SELEX
Jolma et al.(2013)
PAX1_1 		0.729 0.729
PAX9
M03444_2.00 		Homo sapiens
NKCANTSAWGCGTGACS
SGTCACGCWTSANTGMN		 SELEX
Jolma et al.(2013)
PAX9_1 		0.729 0.729
PAX1
M05687_2.00 		Homo sapiens
BCRNTSRWGCGTGACSN
NSGTCACGCWYSANYGV		 SELEX
Yin et al.(2017)
PAX1_eDBD_HT-SELEX 		0.729 0.729
PAX9
M05689_2.00 		Homo sapiens
BHRNYSRDSCGTRACSN
NSGTYACGSHYSRNYDV		 SELEX
Yin et al.(2017)
PAX9_eDBD_HT-SELEX 		0.729 0.729
PAX1
M11207_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX1_B 		0.729 0.729
pax9
M11204_2.00 		Danio rerio Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX9_B 		0.729 0.729
PAX1
M05688_2.00 		Homo sapiens
BCRNTSAWGCGTGACSN
NSGTCACGCWTSANYGV		 SELEX
Yin et al.(2017)
PAX1_eDBD_Methyl-HT-SELEX 		0.729 0.729
PAX9
M05690_2.00 		Homo sapiens
BCRNTSAWSCGYGACNN
NNGTCRCGSWTSANYGV		 SELEX
Yin et al.(2017)
PAX9_eDBD_Methyl-HT-SELEX 		0.729 0.729
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000130714 Paired box 13 96
ENSDARP00000130972 Homeodomain 75 113
ENSDARP00000135767 Paired box 23 161
ENSDARP00000135767 Homeodomain 244 300
ENSDARP00000138421 Paired box 23 138
ENSDARP00000138440 Homeodomain 75 114
ENSDARP00000139430 Paired box 23 147
ENSDARP00000139430 Homeodomain 230 286
ENSDARP00000140503 Paired box 13 151
ENSDARP00000140503 Homeodomain 234 290

Links

Other Homeodomain,Paired box family TFs
Other Danio rerio TFs

Invalid Input OrderBy

2016 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action