PAX6 (Echinops telfairi)
Homeodomain,Paired box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00292 (PAX)
IPR001356
IPR001523
ENSETEG00000002655 T237327_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
PAX6
M00342_2.00
Homo sapiens
NNNRCDMATTANNN

NNNTAATKHGYNNN
PBM
Barrera et al.(2016)
PAX6_REF
0.988 0.988
Pax6
M00540_2.00
Mus musculus
CBAATTAA

TTAATTVG
PBM
Berger et al.(2008)
Pax6_3838
0.988 0.988
PAX6
M03291_2.00
Homo sapiens
DTWYACGCWTGANTGMDYH

DRHKCANTCAWGCGTRWAH
SELEX
Jolma et al.(2013)
PAX6_1
0.988 0.988
PAX6
M05412_2.00
Homo sapiens
NYACGCHYSRNYRMNYN

NRNKYRNYSRDGCGTRN
SELEX
Yin et al.(2017)
PAX6_eDBD_HT-SELEX
0.988 0.988
PAX6
M05414_2.00
Homo sapiens
NYRCGCNYSRNYRVNYN

NRNBYRNYSRNGCGYRN
SELEX
Yin et al.(2017)
PAX6_FL_HT-SELEX
0.988 0.988
PAX6
M02689_2.00
Homo sapiens
TTYACGCWTSANTK

MANTSAWGCGTRAA
SELEX
Mathelier et al.(2014)
MA0069.1
0.988 0.988
PAX6
M09216_2.00
Homo sapiens
TYMYRCWTSRNT

ANYSAWGYRKRA
Misc
Kulakovskiy et al.(2013)
PAX6_HUMAN.H11MO.0.C
0.988 0.988
Pax6
M09217_2.00
Mus musculus
TYMYRCWTSRNT

ANYSAWGYRKRA
Misc
Kulakovskiy et al.(2013)
PAX6_MOUSE.H11MO.0.C
0.988 0.988
PAX6
M10806_2.00
Homo sapiens
NHNNTTYACGCWTSANTKVHH

DDBMANTSAWGCGTRAANNDN
Transfac
Matys et al.(2006)
V$PAX6_01
0.988 0.988
PAX6
M10807_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PAX6_Q2
0.988 0.988
PAX6
M00339_2.00
Homo sapiens
NNNNSGKVGGHNN

NNDCCBMCSNNNN
PBM
Barrera et al.(2016)
PAX6_R128C
0.988 0.988
PAX6
M00344_2.00
Homo sapiens
NNMSASGBYNNN

NNNRVCSTSKNN
PBM
Barrera et al.(2016)
PAX6_V126D
0.988 0.988
PAX6
M05413_2.00
Homo sapiens
DYRCGCWTSRNYRMNYN

NRNKYRNYSAWGCGYRH
SELEX
Yin et al.(2017)
PAX6_eDBD_Methyl-HT-SELEX
0.988 0.988
PAX6
M05415_2.00
Homo sapiens
NYACGCHYSRNYRMHYN

NRDKYRNYSRDGCGTRN
SELEX
Yin et al.(2017)
PAX6_FL_Methyl-HT-SELEX
0.988 0.988
PAX6
M00335_2.00
Homo sapiens
BRNNNNNN

NNNNNNYV
PBM
Barrera et al.(2016)
PAX6_A79E
0.983 0.983
PAX6
M00336_2.00
Homo sapiens
RTGCACAC

GTGTGCAY
PBM
Barrera et al.(2016)
PAX6_F258S
0.983 0.983
PAX6
M00337_2.00
Homo sapiens
NMTAATTANNN

NNNTAATTAKN
PBM
Barrera et al.(2016)
PAX6_P118R
0.983 0.983
PAX6
M00338_2.00
Homo sapiens
WSGVRVDR

YHBYBCSW
PBM
Barrera et al.(2016)
PAX6_P68S
0.983 0.983
PAX6
M00340_2.00
Homo sapiens
NNNNNRN

NYNNNNN
PBM
Barrera et al.(2016)
PAX6_R242T
0.983 0.983
PAX6
M00341_2.00
Homo sapiens
BTSCCCSGSC

GSCSGGGSAV
PBM
Barrera et al.(2016)
PAX6_R26G
0.983 0.983
PAX6
M00343_2.00
Homo sapiens
NNNNCCCVKCNBN

NVNGMBGGGNNNN
PBM
Barrera et al.(2016)
PAX6_S119R
0.983 0.983
ey
M03896_2.00
Drosophila melanogaster
CKAATTAD

HTAATTMG
SELEX
Nitta et al.(2015)
ey_1
0.919 0.919
ey
M03897_2.00
Drosophila melanogaster
HTAATCKMATTAD

HTAATKMGATTAD
SELEX
Nitta et al.(2015)
ey_2
0.919 0.919
ey
M03898_2.00
Drosophila melanogaster
WAAYYRRTTN

NAAYYRRTTW
SELEX
Nitta et al.(2015)
ey_3
0.919 0.919
toy
M03899_2.00
Drosophila melanogaster
TTYACGCWTGASTGMACAN

NTGTKCASTCAWGCGTRAA
SELEX
Nitta et al.(2015)
toy_1
0.890 0.890
toy
M03900_2.00
Drosophila melanogaster
NTYACGCWTSAVTGMRCNN

NNGYKCABTSAWGCGTRAN
SELEX
Nitta et al.(2015)
toy_2
0.890 0.890
toy
M03901_2.00
Drosophila melanogaster
VATTANBHAYGSWYSRN

NYSRWSCRTDVNTAATB
SELEX
Nitta et al.(2015)
toy_3
0.890 0.890
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSETEP00000002163 Paired box 4 139
ENSETEP00000002163 Homeodomain 225 281

Links

Other Homeodomain,Paired box family TFs
Other Echinops telfairi TFs

191 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
PAX6 Myotis lucifugus ENSMLUG00000006517 I 0.988
PAX6 Macaca mulatta ENSMMUG00000016810 I 0.988
ENSMPUG00000011295 Mustela putorius furo ENSMPUG00000011295 I 0.988
Pax6 Mus musculus ENSMUSG00000027168 D 0.988
PAX6 Microcebus murinus ENSMICG00000004089 I 0.988
PAX6 Gorilla gorilla ENSGGOG00000010246 I 0.988
ENSCSAG00000005253 Chlorocebus sabaeus ENSCSAG00000005253 I 0.988
PAX6 Dasypus novemcinctus ENSDNOG00000000761 I 0.988
PAX6 Homo sapiens ENSG00000007372 D 0.988
PAX6 Gallus gallus ENSGALG00000012123 I 0.988
ENSOARG00000016191 Ovis aries ENSOARG00000016191 I 0.988
PAX6 Otolemur garnettii ENSOGAG00000007857 I 0.988
PAX6 Sorex araneus ENSSARG00000011424 I 0.988
ENSSHAG00000016310 Sarcophilus harrisii ENSSHAG00000016310 I 0.988
PAX6 Sus scrofa ENSSSCG00000013320 I 0.988
ENSSTOG00000003211 Ictidomys tridecemlineatus ENSSTOG00000003211 I 0.988
Pax6 Rattus norvegicus ENSRNOG00000004410 I 0.988
ENSPSIG00000012748 Pelodiscus sinensis ENSPSIG00000012748 I 0.988
PAX6 Ochotona princeps ENSOPRG00000001678 I 0.988
ENSPANG00000005448 Papio anubis ENSPANG00000005448 I 0.988
PAX6 Procavia capensis ENSPCAG00000005165 I 0.988
PAX6 Callithrix jacchus ENSCJAG00000005942 I 0.988
PAX6 Monodelphis domestica ENSMODG00000009611 I 0.988
Pvit_09512 Pogona vitticeps Pvit_09512 I 0.988
pax6 Xenopus tropicalis XB-GENE-484088 I 0.988
PAX6 Anolis carolinensis ENSACAG00000002252 I 0.988
PAX6 Bos taurus ENSBTAG00000004561 I 0.988
ENSGMOG00000012304 Gadus morhua ENSGMOG00000012304 I 0.983
ENSP00000368401-D1 Bos grunniens ENSP00000368401-D1 I 0.983
ENSLACG00000015337 Latimeria chalumnae ENSLACG00000015337 I 0.983
ENSAMEG00000006908 Ailuropoda melanoleuca ENSAMEG00000006908 I 0.983
PAX6 Loxodonta africana ENSLAFG00000015520 I 0.983
PAX6 Cavia porcellus ENSCPOG00000007245 I 0.983
ENSLOCG00000004578 Lepisosteus oculatus ENSLOCG00000004578 I 0.983
ENSP00000368424 Macaca fascicularis ENSP00000368424 I 0.983
PAX6 Tupaia belangeri ENSTBEG00000004748 I 0.983
PAX6 Equus caballus ENSECAG00000021000 I 0.983
pax6b Danio rerio ENSDARG00000045936 I 0.983
PAX6 Oryctolagus cuniculus ENSOCUG00000011075 I 0.983
ENSNLEG00000017888 Nomascus leucogenys ENSNLEG00000017888 I 0.983
Alligator_sinensis_CCG012954.1 Alligator sinensis Alligator_sinensis_CCG012954.1 I 0.983
PAX6 Felis catus ENSFCAG00000007094 I 0.983
pax6a Danio rerio ENSDARG00000103379 I 0.983
pax6b Oryzias latipes ENSORLG00000009913 I 0.977
ENSPFOG00000016987 Poecilia formosa ENSPFOG00000016987 I 0.977
ENSONIG00000005541 Oreochromis niloticus ENSONIG00000005541 I 0.977
pax6.L Xenopus laevis XB-GENE-865046 I 0.977
pax6.S Xenopus laevis XB-GENE-6464331 I 0.977
pax6b Gasterosteus aculeatus ENSGACG00000016030 I 0.977
pax6b Takifugu rubripes ENSTRUG00000006935 I 0.971
pax6b Tetraodon nigroviridis ENSTNIG00000013804 I 0.971
ENSXMAG00000014260 Xiphophorus maculatus ENSXMAG00000014260 I 0.971
ENSONIG00000004074 Oreochromis niloticus ENSONIG00000004074 I 0.965
ENSAMXG00000001228 Astyanax mexicanus ENSAMXG00000001228 I 0.960
ENSXMAG00000016421 Xiphophorus maculatus ENSXMAG00000016421 I 0.960
ENSORLG00000000847 Oryzias latipes ENSORLG00000000847 I 0.954
ENSGACG00000002490 Gasterosteus aculeatus ENSGACG00000002490 I 0.942
ENSTNIG00000002471 Tetraodon nigroviridis ENSTNIG00000002471 I 0.931
Sakowv30026828m.g Saccoglossus kowalevskii Sakowv30026828m.g I 0.931
TC008176 Tribolium castaneum TC008176 I 0.925
ey Drosophila pseudoobscura FBgn0018538 I 0.925
ey Drosophila persimilis FBgn0043659 I 0.925
SMAR013763 Strigamia maritima SMAR013763 I 0.925
GI14081 Drosophila mojavensis FBgn0136835 I 0.925
GK13702 Drosophila willistoni FBgn0215710 I 0.925
ey Drosophila melanogaster FBgn0005558 D 0.919
GB50342 Apis mellifera GB50342 I 0.919
ey Drosophila virilis FBgn0028754 I 0.919
NV15820 Nasonia vitripennis NV15820 I 0.919
ACYPI067710 Acyrthosiphon pisum ACYPI067710 I 0.919
Ogr12767 Ophisaurus gracilis Ogr12767 I 0.919
GG16399 Drosophila erecta FBgn0108631 I 0.919
GE14559 Drosophila yakuba FBgn0232158 I 0.919
ey Drosophila sechellia FBgn0068720 I 0.919
ENSAMXG00000013008 Astyanax mexicanus ENSAMXG00000013008 I 0.918
L798_00712 Zootermopsis nevadensis L798_00712 I 0.913
DAPPUDRAFT_249978 Daphnia pulex DAPPUDRAFT_249978 I 0.913
HelroG80374 Helobdella robusta HelroG80374 I 0.913
Cmyd_10016391 Chelonia mydas Cmyd_10016391 I 0.913
DAPPUDRAFT_249991 Daphnia pulex DAPPUDRAFT_249991 I 0.908
Afo_R014630 Aptenodytes forsteri Afo_R014630 I 0.902
TC007409 Tribolium castaneum TC007409 I 0.902
ENSTRUG00000017375 Takifugu rubripes ENSTRUG00000017375 I 0.901
GI14042 Drosophila mojavensis FBgn0136796 I 0.896
GH23963 Drosophila grimshawi FBgn0131420 I 0.896
ENSCING00000006503 Ciona intestinalis ENSCING00000006503 I 0.896
GL17563 Drosophila persimilis FBgn0155166 I 0.896
GK13683 Drosophila willistoni FBgn0215691 I 0.896
GJ13300 Drosophila virilis FBgn0200526 I 0.896
ENSPPYG00000003386 Pongo abelii ENSPPYG00000003386 I 0.896
ENSGMOG00000019087 Gadus morhua ENSGMOG00000019087 I 0.896
ISCW021772 Ixodes scapularis ISCW021772 I 0.896
ENSCSAVG00000007987 Ciona savignyi ENSCSAVG00000007987 I 0.896
ACYPI008177 Acyrthosiphon pisum ACYPI008177 I 0.896
GA27636 Drosophila pseudoobscura FBgn0249001 I 0.896
L798_11483 Zootermopsis nevadensis L798_11483 I 0.895
GE14563 Drosophila yakuba FBgn0232162 I 0.890
GM13021 Drosophila sechellia FBgn0167952 I 0.890
GG16402 Drosophila erecta FBgn0108634 I 0.890
toy Drosophila melanogaster FBgn0019650 D 0.890
GF21877 Drosophila ananassae FBgn0098877 I 0.890
CGI_10027695 Crassostrea gigas CGI_10027695 I 0.885
TMUE_s0038005250 Trichuris muris TMUE_s0038005250 I 0.884
TTRE_0000173501 Trichuris trichiura TTRE_0000173501 I 0.884
GF22818 Drosophila ananassae FBgn0099812 I 0.879
PHUM097050 Pediculus humanus PHUM097050 I 0.867
ISCW006352 Ixodes scapularis ISCW006352 I 0.867
SMU15027897 Schmidtea mediterranea SMU15027897 I 0.861
GB41504 Apis mellifera GB41504 I 0.857
NV17076 Nasonia vitripennis NV17076 I 0.857
Cflo_00481--XP_394648.3_APIME Camponotus floridanus Cflo_00481--XP_394648.3_APIME I 0.857
Hsal_09597--XP_394648.3_APIME Harpegnathos saltator Hsal_09597--XP_394648.3_APIME I 0.857
LotgiG133720 Lottia gigantea LotgiG133720 I 0.852
tetur09g00660 Tetranychus urticae tetur09g00660 I 0.850
D915_07175 Fasciola hepatica D915_07175 I 0.850
L596_g12356 Steinernema carpocapsae L596_g12356 I 0.844
ACUA021227 Anopheles culicifacies ACUA021227 I 0.844
AFUN011575 Anopheles funestus AFUN011575 I 0.844
AEPI005803 Anopheles epiroticus AEPI005803 I 0.844
AMEC021831 Anopheles melas AMEC021831 I 0.844
L892_g3713 Steinernema scapterisci L892_g3713 I 0.844
RSKR_0000862000 Rhabditophanes kr3021 RSKR_0000862000 I 0.838
MCINX016249 Melitaea cinxia MCINX016249 I 0.838
ASIS012617 Anopheles sinensis ASIS012617 I 0.838
D918_01592 Trichuris suis D918_01592 I 0.835
AALB006643 Anopheles albimanus AALB006643 I 0.832
CBN04513 Caenorhabditis brenneri CBN04513 I 0.832
ACUA016154 Anopheles culicifacies ACUA016154 I 0.832
AAEL002321 Aedes aegypti AAEL002321 I 0.832
CRE07226 Caenorhabditis remanei CRE07226 I 0.832
AATE014626 Anopheles atroparvus AATE014626 I 0.827
AARA001110 Anopheles arabiensis AARA001110 I 0.827
GD24416 Drosophila simulans FBgn0195753 I 0.827
ACHR009845 Anopheles christyi ACHR009845 I 0.827
AFUN011570 Anopheles funestus AFUN011570 I 0.827
AQUA008313 Anopheles quadriannulatus AQUA008313 I 0.827
AMIN002132 Anopheles minimus AMIN002132 I 0.827
AMEM002691 Anopheles merus AMEM002691 I 0.827
AMEC013051 Anopheles melas AMEC013051 I 0.827
AEPI005798 Anopheles epiroticus AEPI005798 I 0.827
AFAF017899 Anopheles farauti AFAF017899 I 0.827
ADIR000973 Anopheles dirus ADIR000973 I 0.827
ASTEI06205 Anopheles stephensi ASTEI06205 I 0.827
AGAP000067 Anopheles gambiae AGAP000067 I 0.827
Smp_160670 Schistosoma mansoni Smp_160670 I 0.827
SMTD_0000837201 Schistosoma mattheei SMTD_0000837201 I 0.827
A_05170 Schistosoma haematobium A_05170 I 0.827
HelroG173449 Helobdella robusta HelroG173449 I 0.827
CPIJ006398 Culex quinquefasciatus CPIJ006398 I 0.821
PTRK_0000512100 Parastrongyloides trichosuri PTRK_0000512100 I 0.821
CpipJ_CPIJ006398 Culex pipiens CpipJ_CPIJ006398 I 0.821
SVE_0819200 Strongyloides venezuelensis SVE_0819200 I 0.815
SPAL_0001466800 Strongyloides papillosus SPAL_0001466800 I 0.815
vab-3 Caenorhabditis elegans WBGene00006870 I 0.815
Smp_170750 Schistosoma mansoni Smp_170750 I 0.809
EFV57892 Trichinella spiralis EFV57892 I 0.809
CPIJ006390 Culex quinquefasciatus CPIJ006390 I 0.809
CpipJ_CPIJ006390 Culex pipiens CpipJ_CPIJ006390 I 0.809
AALB006354 Anopheles albimanus AALB006354 I 0.808
BXY_1643500 Bursaphelenchus xylophilus BXY_1643500 I 0.803
ASIS012967 Anopheles sinensis ASIS012967 I 0.802
ASTEI06200 Anopheles stephensi ASTEI06200 I 0.802
AQUA008308 Anopheles quadriannulatus AQUA008308 I 0.802
AARA001115 Anopheles arabiensis AARA001115 I 0.802
AMIN002127 Anopheles minimus AMIN002127 I 0.802
AGAP000063 Anopheles gambiae AGAP000063 I 0.802
T265_09221 Opisthorchis viverrini T265_09221 I 0.791
AFAF009619 Anopheles farauti AFAF009619 I 0.789
ADAC003449 Anopheles darlingi ADAC003449 I 0.786
csin110224 Clonorchis sinensis csin110224 I 0.780
ACHR008920 Anopheles christyi ACHR008920 I 0.775
SSTP_0001059400 Strongyloides stercoralis SSTP_0001059400 I 0.775
T265_14971 Opisthorchis viverrini T265_14971 I 0.775
ENSMEUG00000015900 Macropus eugenii ENSMEUG00000015900 I 0.763
D917_00854 Trichinella nativa D917_00854 I 0.758
PAX6 Pan troglodytes ENSPTRG00000003474 I 0.746
PAX6 Ornithorhynchus anatinus ENSOANG00000015149 I 0.746
ENSFALG00000010839 Ficedula albicollis ENSFALG00000010839 I 0.746
ADAC001560 Anopheles darlingi ADAC001560 I 0.746
Gfo_R001537 Geospiza fortis Gfo_R001537 I 0.746
ENSAPLG00000004928 Anas platyrhynchos ENSAPLG00000004928 I 0.746
Aan_R006618 Calypte anna Aan_R006618 I 0.746
MCOS_0000220101 Mesocestoides corti MCOS_0000220101 I 0.742
NEMVEDRAFT_v1g239535 Nematostella vectensis NEMVEDRAFT_v1g239535 I 0.740
ADIR000968 Anopheles dirus ADIR000968 I 0.732
TsM_000166900 Taenia solium TsM_000166900 I 0.728
LLOJ005149 Lutzomyia longipalpis LLOJ005149 I 0.728
ENSTSYG00000011965 Tarsius syrichta ENSTSYG00000011965 I 0.723
PAX6 Tursiops truncatus ENSTTRG00000002399 I 0.718
TTAC_0000231001 Hydatigera taeniaeformis TTAC_0000231001 I 0.717
NEMVEDRAFT_v1g168908 Nematostella vectensis NEMVEDRAFT_v1g168908 I 0.711