TF Information

PAX7 *(Homo sapiens)* Homeodomain,Paired box
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00046 (Homeobox) PF00292 (PAX)	IPR001356 IPR001523	ENSG00000009709	T237340_2.00	Ensembl (2018-Dec-8)	Link out
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
PAX7 M00345_2.00	Homo sapiens	NSGTCACGSN	NSCGTGACSN	PBM Barrera et al.(2016) PAX7_P112L	(Direct)	(Direct)
PAX7 M00346_2.00	Homo sapiens	NGTYAYGSHN	NDSCRTRACN	PBM Barrera et al.(2016) PAX7_REF	(Direct)	(Direct)
PAX7 M03292_2.00	Homo sapiens	WAATYRATTA	TAATYRATTW	SELEX Jolma et al.(2013) PAX7_1	(Direct)	(Direct)
PAX7 M03293_2.00	Homo sapiens	TAATYGATTA	TAATCRATTA	SELEX Jolma et al.(2013) PAX7_2	(Direct)	(Direct)
PAX7 M05416_2.00	Homo sapiens	NDSCGTGACGAATYR	YRATTCGTCACGSHN	SELEX Yin et al.(2017) PAX7_eDBD_HT-SELEX_1	(Direct)	(Direct)
PAX7 M05417_2.00	Homo sapiens	NSGTCACGSHWRTTAN	NTAAYWDSCGTGACSN	SELEX Yin et al.(2017) PAX7_eDBD_HT-SELEX_2	(Direct)	(Direct)
PAX7 M05418_2.00	Homo sapiens	NNAATCRATTWN	NWAATYGATTNN	SELEX Yin et al.(2017) PAX7_eDBD_HT-SELEX_3	(Direct)	(Direct)
PAX7 M05419_2.00	Homo sapiens	NVATTVGTCRCGSYN	NRSCGYGACBAATBN	SELEX Yin et al.(2017) PAX7_eDBD_Methyl-HT-SELEX_1	(Direct)	(Direct)
PAX7 M05420_2.00	Homo sapiens	NNGTCACGSHHRTTAN	NTAAYDDSCGTGACNN	SELEX Yin et al.(2017) PAX7_eDBD_Methyl-HT-SELEX_2	(Direct)	(Direct)
PAX7 M05421_2.00	Homo sapiens	NNAATCRATTWN	NWAATYGATTNN	SELEX Yin et al.(2017) PAX7_eDBD_Methyl-HT-SELEX_3	(Direct)	(Direct)
PAX7 M05422_2.00	Homo sapiens	BVATTMGTCACGSHN	NDSCGTGACKAATBV	SELEX Yin et al.(2017) PAX7_FL_HT-SELEX_1	(Direct)	(Direct)
PAX7 M05423_2.00	Homo sapiens	NSGTCACGSYWATTAN	NTAATWRSCGTGACSN	SELEX Yin et al.(2017) PAX7_FL_HT-SELEX_2	(Direct)	(Direct)
PAX7 M05424_2.00	Homo sapiens	NTAATYGATTAN	NTAATCRATTAN	SELEX Yin et al.(2017) PAX7_FL_HT-SELEX_3	(Direct)	(Direct)
PAX7 M05425_2.00	Homo sapiens	YRATTMGTCACGSHN	NDSCGTGACKAATYR	SELEX Yin et al.(2017) PAX7_FL_Methyl-HT-SELEX_1	(Direct)	(Direct)
PAX7 M05426_2.00	Homo sapiens	NSGTCACGSYWATTAN	NTAATWRSCGTGACSN	SELEX Yin et al.(2017) PAX7_FL_Methyl-HT-SELEX_2	(Direct)	(Direct)
PAX7 M05427_2.00	Homo sapiens	NTAATYGATTAN	NTAATCRATTAN	SELEX Yin et al.(2017) PAX7_FL_Methyl-HT-SELEX_3	(Direct)	(Direct)
PAX7 M05874_2.00	Homo sapiens	ATTMGTYACGSHN	NDSCGTRACKAAT	SMiLE-seq Isakova et al.(2017) PAX7	(Direct)	(Direct)
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
Pax7 M00541_2.00	Mus musculus	NNVATTWN	NWAATBNN	PBM Berger et al.(2008) Pax7_3783	1.000	1.000
PAX1 M03442_2.00	Homo sapiens	DBCANTSAWGCGTGACS	SGTCACGCWTSANTGVH	SELEX Jolma et al.(2013) PAX1_1	0.744	0.744
PAX9 M03444_2.00	Homo sapiens	NKCANTSAWGCGTGACS	SGTCACGCWTSANTGMN	SELEX Jolma et al.(2013) PAX9_1	0.744	0.744
PAX1 M05687_2.00	Homo sapiens	BCRNTSRWGCGTGACSN	NSGTCACGCWYSANYGV	SELEX Yin et al.(2017) PAX1_eDBD_HT-SELEX	0.752	0.752
PAX9 M05689_2.00	Homo sapiens	BHRNYSRDSCGTRACSN	NSGTYACGSHYSRNYDV	SELEX Yin et al.(2017) PAX9_eDBD_HT-SELEX	0.752	0.752
PAX1 M11207_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX1_B	0.744	0.744
PAX1 M05688_2.00	Homo sapiens	BCRNTSAWGCGTGACSN	NSGTCACGCWTSANYGV	SELEX Yin et al.(2017) PAX1_eDBD_Methyl-HT-SELEX	0.744	0.744
PAX9 M05690_2.00	Homo sapiens	BCRNTSAWSCGYGACNN	NNGTCRCGSWTSANYGV	SELEX Yin et al.(2017) PAX9_eDBD_Methyl-HT-SELEX	0.744	0.744
pax2 M02428_2.00	Xenopus tropicalis	NNNRNBCRNN	NNYGVNYNNN	PBM Weirauch et al.(2014) pTH8556	0.736	0.736
Pax7 M09586_2.00	Mus musculus	NNNNNYAATTDNNHAATTAN	NTAATTDNNHAATTRNNNNN	Misc Heinz et al.(2010) Myoblast-Pax7_GSE25064_1	1.000	1.000
pax9 M11204_2.00	Danio rerio	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX9_B	0.736	0.736
Pax7 M09587_2.00	Mus musculus	DTAATYDGATTA	TAATCHRATTAH	Misc Heinz et al.(2010) Myoblast-Pax7_GSE25064_2	1.000	1.000
pax2b M02425_2.00	Danio rerio	HVNYSRNSCR	YGSNYSRNBD	PBM Weirauch et al.(2014) pTH8679	0.728	0.728
Pax5B M01301_2.00	Gallus gallus	NSNDTNNNN	NNNNAHNSN	PBM Lambert et al.(2019) pTH9781	0.736	0.736
Pax7 M09588_2.00	Mus musculus	TAATTGATTW	WAATCAATTA	Misc Heinz et al.(2010) Myoblast-Pax7_GSE25064_3	1.000	1.000
PAX5 M03443_2.00	Homo sapiens	RNBYANYSAWSCGTRACN	NGTYACGSWTSRNTRVNY	SELEX Jolma et al.(2013) PAX5_1	0.736	0.736
PAX5 M08160_2.00	Homo sapiens	RDGCGTGACCNN	NNGGTCACGCHY	ChIP-seq Mathelier et al.(2014) MA0014.3	0.728	0.728
PAX5 M07995_2.00	Homo sapiens	BCAVYSRDSCRKRRC	GYYMYGSHYSRBTGV	ChIP-seq Gerstein et al.(2012) GM12878_PAX5C20_HudsonAlpha	0.728	0.728
PAX5 M07996_2.00	Homo sapiens	BCASYSRDSCRTRAC	GTYAYGSHYSRSTGV	ChIP-seq Gerstein et al.(2012) GM12878_PAX5N19_HudsonAlpha	0.728	0.728
PAX5 M07997_2.00	Homo sapiens	CASYSRDSCRKRACN	NGTYMYGSHYSRSTG	ChIP-seq Gerstein et al.(2012) GM12891_PAX5C20_HudsonAlpha	0.728	0.728
PAX5 M07998_2.00	Homo sapiens	BCASYSRDSCGKRRC	GYYMCGSHYSRSTGV	ChIP-seq Gerstein et al.(2012) GM12892_PAX5C20_HudsonAlpha	0.728	0.728
PAX3 M00358_2.00	Homo sapiens	NRTNNNN	NNNNAYN	PBM Barrera et al.(2016) PAX3_REF	0.951	0.951
PAX5 M08227_2.00	Homo sapiens	BCANYSRDGCGTRAM	KTYACGCHYSRNTGV	ChIP-seq Contrino et al.(2012) Mv108	0.728	0.728
PAX5 M08228_2.00	Homo sapiens	AGCGTGRCYG	CRGYCACGCT	ChIP-seq Contrino et al.(2012) Mv109	0.736	0.736
PAX3 M03297_2.00	Homo sapiens	TAATYRATTA	TAATYRATTA	SELEX Jolma et al.(2013) PAX3_1	0.951	0.951
PAX5 M09341_2.00	Homo sapiens	SNVDGNKCARCVRAGCRDGAC	GTCHYGCTYBGYTGMNCHBNS	Misc Kulakovskiy et al.(2013) PAX5_HUMAN.H11MO.0.A	0.736	0.736
PAX3 M03885_2.00	Homo sapiens	NNTAATYGATTANN	NNTAATCRATTANN	SELEX Nitta et al.(2015) PAX3_1	0.951	0.951
PAX3 M03886_2.00	Homo sapiens	RATTMGTCACGST	ASCGTGACKAATY	SELEX Nitta et al.(2015) PAX3_2	0.951	0.951
Pax5 M09342_2.00	Mus musculus	VDRNBCAVYVRDSCRKRRM	KYYMYGSHYBRBTGVNYHB	Misc Kulakovskiy et al.(2013) PAX5_MOUSE.H11MO.0.A	0.728	0.728
PAX3 M05438_2.00	Homo sapiens	NSGTCACGSHHATTAN	NTAATDDSCGTGACSN	SELEX Yin et al.(2017) PAX3_eDBD_HT-SELEX_1	0.951	0.951
PAX5 M09622_2.00	Homo sapiens	BCASYSRDSCRTGRMN	NKYCAYGSHYSRSTGV	Misc Heinz et al.(2010) GM12878-PAX5_GSE32465_1	0.728	0.728
PAX3 M05439_2.00	Homo sapiens	NDAATCRATTMN	NKAATYGATTHN	SELEX Yin et al.(2017) PAX3_eDBD_HT-SELEX_2	0.951	0.951
PAX5 M09623_2.00	Homo sapiens	BCABNVRSCGTGAC	GTCACGSYBNVTGV	Misc Heinz et al.(2010) GM12878-PAX5_GSE32465_2	0.728	0.728
PAX3 M05440_2.00	Homo sapiens	NBRATTMGTCACGSHN	NDSCGTGACKAATYVN	SELEX Yin et al.(2017) PAX3_eDBD_HT-SELEX_3	0.951	0.951
PAX5 M11208_2.00	Homo sapiens	BCNNNRNKCANBGNWGNRKRGMSRSHNB	VNDSYSKCYMYNCWNCVNTGMNYNNNGV	Transfac Matys et al.(2006) V$PAX5_01	0.728	0.728
PAX3 M09585_2.00	Homo sapiens	WSYRTGACWAATBNN	NNVATTWGTCAYRSW	Misc Heinz et al.(2010) Rh4-PAX3_FKHR_GSE19063	0.951	0.951
PAX5 M11209_2.00	Homo sapiens	VRHVDGDNDBBTNRAGCGKRACVRYNVH	DBNRYBGTYMCGCTYNAVVHNHCHBDYB	Transfac Matys et al.(2006) V$PAX5_02	0.728	0.728
PAX3 M10816_2.00	Homo sapiens	TCGTCACRCHYHM	KDRDGYGTGACGA	Transfac Matys et al.(2006) V$PAX3_01	0.951	0.951
PAX5 M11210_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX5_06	0.728	0.728
PAX5 M11211_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX5_07	0.736	0.736
PAX3 M10817_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX3_B	0.951	0.951
PAX5 M11212_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX5_Q6	0.736	0.736
PAX3 M05441_2.00	Homo sapiens	NNGTCACGSHWRTTAN	NTAAYWDSCGTGACNN	SELEX Yin et al.(2017) PAX3_eDBD_Methyl-HT-SELEX_1	0.951	0.951
PAX3 M05442_2.00	Homo sapiens	NWAATCRATTAN	NTAATYGATTWN	SELEX Yin et al.(2017) PAX3_eDBD_Methyl-HT-SELEX_2	0.951	0.951
Poxm M03944_2.00	Drosophila melanogaster	CAVTCAWGCGTGACR	YGTCACGCWTGABTG	SELEX Nitta et al.(2015) Poxm_1	0.720	0.720
PAX3 M05443_2.00	Homo sapiens	NNRATTVGTCRCGSHN	NDSCGYGACBAATYNN	SELEX Yin et al.(2017) PAX3_eDBD_Methyl-HT-SELEX_3	0.951	0.951
Poxm M03945_2.00	Drosophila melanogaster	NYSAWGCRTRACS	SGTYAYGCWTSRN	SELEX Nitta et al.(2015) Poxm_2	0.720	0.720
PAX3 M00352_2.00	Homo sapiens	VNTAATYR	YRATTANB	PBM Barrera et al.(2016) PAX3_G48R	0.945	0.945
Poxm M06436_2.00	Drosophila melanogaster	NNNNNNMVNHNRNSCRTGA	TCAYGSNYNDNBKNNNNNN	B1H Zhu et al.(2011) Poxm_SOLEXA_5_FBgn0003129	0.720	0.720
PAX3 M00353_2.00	Homo sapiens	NNNNRTNNN	NNNAYNNNN	PBM Barrera et al.(2016) PAX3_N47H	0.945	0.945
PAX8 M05685_2.00	Homo sapiens	NRNBYRNYSRWGCGTGACSN	NSGTCACGCWYSRNYRVNYN	SELEX Yin et al.(2017) PAX8_FL_HT-SELEX	0.712	0.712
PAX3 M00354_2.00	Homo sapiens	NNNRYNN	NNRYNNN	PBM Barrera et al.(2016) PAX3_N47K	0.945	0.945
Pax8 M09624_2.00	Rattus norvegicus	BCAGBCADSCRKGVM	KBCMYGSHTGVCTGV	Misc Heinz et al.(2010) Thyroid-Pax8_GSE26938	0.712	0.712
PAX3 M00355_2.00	Homo sapiens	NNNATNWNN	NNWNATNNN	PBM Barrera et al.(2016) PAX3_P50L	0.945	0.945
PAX8 M11205_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX8_01	0.712	0.712
PAX8 M11206_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX8_B	0.720	0.720
PAX3 M00356_2.00	Homo sapiens	NNKWCAYDDWN	NWHHRTGWMNN	PBM Barrera et al.(2016) PAX3_R270C	0.945	0.945
PAX8 M05686_2.00	Homo sapiens	NRNBCRNTSAWSCGYGACNN	NNGTCRCGSWTSANYGVNYN	SELEX Yin et al.(2017) PAX8_FL_Methyl-HT-SELEX	0.720	0.720
PAX3 M00357_2.00	Homo sapiens	NNNATNWNN	NNWNATNNN	PBM Barrera et al.(2016) PAX3_R56L	0.945	0.945
PAX3 M00359_2.00	Homo sapiens	NTAATYRV	BYRATTAN	PBM Barrera et al.(2016) PAX3_Y90H	0.945	0.945
prd M03894_2.00	Drosophila melanogaster	VATTVGTCACGS	SCGTGACBAATB	SELEX Nitta et al.(2015) prd_1	0.824	0.824
prd M03895_2.00	Drosophila melanogaster	NRATCRATYN	NRATYGATYN	SELEX Nitta et al.(2015) prd_2	0.824	0.824
prd M06555_2.00	Drosophila melanogaster	HSWAACNGH	DCNGTTWSD	B1H Mathelier et al.(2014) MA0239.1	0.824	0.824
prd M09684_2.00	Drosophila melanogaster	HMVNTHHKWMACGS	SCGTKWMDDANBKD	Misc Kulakovskiy et al.(2009) prd	0.824	0.824
prd M10818_2.00	Drosophila melanogaster	Transfac license required	Transfac license required	Transfac Matys et al.(2006) I$PRD_Q6	0.824	0.824
gsb-n M03888_2.00	Drosophila melanogaster	SCGTRWCKAATB	VATTMGWYACGS	SELEX Nitta et al.(2015) gsb-n_1	0.780	0.780
gsb M03889_2.00	Drosophila melanogaster	RATTMGTCACGSN	NSCGTGACKAATY	SELEX Nitta et al.(2015) gsb_1	0.775	0.775
gsb M03890_2.00	Drosophila melanogaster	NNNAATCRATTWNN	NNWAATYGATTNNN	SELEX Nitta et al.(2015) gsb_2	0.775	0.775
gsb M03891_2.00	Drosophila melanogaster	RTBDMTAATTGATTD	HAATCAATTAKHVAY	SELEX Nitta et al.(2015) gsb_3	0.775	0.775
gsb M03892_2.00	Drosophila melanogaster	NNTAATYGATTANN	NNTAATCRATTANN	SELEX Nitta et al.(2015) gsb_4	0.775	0.775
gsb M03893_2.00	Drosophila melanogaster	NSCGTGACKAATBV	BVATTMGTCACGSN	SELEX Nitta et al.(2015) gsb_5	0.775	0.775
For this family, TFs with SR scores > 0.700* will likely have a similar motif*

Experimental Constructs

Motif ID	Domain	From	To	Sequence
M00345_2.00	Paired box	15	140	GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATLDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRVLR
M00346_2.00	Paired box	15	140	GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRVLR

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
ENSP00000364524	Paired box	34	161	GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLR
ENSP00000364524	Homeodomain	218	274	RRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRK
ENSP00000383502	Paired box	34	159	GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRVLR
ENSP00000403389	Paired box	34	159	GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATLDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRVLR

Links
Other Homeodomain,Paired box family TFs
Other *Homo sapiens* TFs

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706 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action

PAX7 (Homo sapiens) Homeodomain,Paired box

TF Information

Directly determined binding motifs

Motifs from related TFs

Experimental Constructs

DNA Binding Domains

Links

706 Related TFs

Invalid Input OrderBy

PAX7 **(Homo sapiens)
Homeodomain,Paired box**