PAX3 (Homo sapiens)
Homeodomain,Paired box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00292 (PAX) 		IPR001356
IPR001523 		ENSG00000135903 T237343_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
PAX3
M00352_2.00		 Homo sapiens
VNTAATYR
YRATTANB		 PBM
Barrera et al.(2016)
PAX3_G48R		 (Direct) (Direct)
PAX3
M00353_2.00		 Homo sapiens
NNNNRTNNN
NNNAYNNNN		 PBM
Barrera et al.(2016)
PAX3_N47H		 (Direct) (Direct)
PAX3
M00354_2.00		 Homo sapiens
NNNRYNN
NNRYNNN		 PBM
Barrera et al.(2016)
PAX3_N47K		 (Direct) (Direct)
PAX3
M00355_2.00		 Homo sapiens
NNNATNWNN
NNWNATNNN		 PBM
Barrera et al.(2016)
PAX3_P50L		 (Direct) (Direct)
PAX3
M00356_2.00		 Homo sapiens
NNKWCAYDDWN
NWHHRTGWMNN		 PBM
Barrera et al.(2016)
PAX3_R270C		 (Direct) (Direct)
PAX3
M00357_2.00		 Homo sapiens
NNNATNWNN
NNWNATNNN		 PBM
Barrera et al.(2016)
PAX3_R56L		 (Direct) (Direct)
PAX3
M00358_2.00		 Homo sapiens
NRTNNNN
NNNNAYN		 PBM
Barrera et al.(2016)
PAX3_REF		 (Direct) (Direct)
PAX3
M00359_2.00		 Homo sapiens
NTAATYRV
BYRATTAN		 PBM
Barrera et al.(2016)
PAX3_Y90H		 (Direct) (Direct)
PAX3
M03297_2.00		 Homo sapiens
TAATYRATTA
TAATYRATTA		 SELEX
Jolma et al.(2013)
PAX3_1		 (Direct) (Direct)
PAX3
M03885_2.00		 Homo sapiens
NNTAATYGATTANN
NNTAATCRATTANN		 SELEX
Nitta et al.(2015)
PAX3_1		 (Direct) (Direct)
PAX3
M03886_2.00		 Homo sapiens
RATTMGTCACGST
ASCGTGACKAATY		 SELEX
Nitta et al.(2015)
PAX3_2		 (Direct) (Direct)
PAX3
M05438_2.00		 Homo sapiens
NSGTCACGSHHATTAN
NTAATDDSCGTGACSN		 SELEX
Yin et al.(2017)
PAX3_eDBD_HT-SELEX_1		 (Direct) (Direct)
PAX3
M05439_2.00		 Homo sapiens
NDAATCRATTMN
NKAATYGATTHN		 SELEX
Yin et al.(2017)
PAX3_eDBD_HT-SELEX_2		 (Direct) (Direct)
PAX3
M05440_2.00		 Homo sapiens
NBRATTMGTCACGSHN
NDSCGTGACKAATYVN		 SELEX
Yin et al.(2017)
PAX3_eDBD_HT-SELEX_3		 (Direct) (Direct)
PAX3
M05441_2.00		 Homo sapiens
NNGTCACGSHWRTTAN
NTAAYWDSCGTGACNN		 SELEX
Yin et al.(2017)
PAX3_eDBD_Methyl-HT-SELEX_1		 (Direct) (Direct)
PAX3
M05442_2.00		 Homo sapiens
NWAATCRATTAN
NTAATYGATTWN		 SELEX
Yin et al.(2017)
PAX3_eDBD_Methyl-HT-SELEX_2		 (Direct) (Direct)
PAX3
M05443_2.00		 Homo sapiens
NNRATTVGTCRCGSHN
NDSCGYGACBAATYNN		 SELEX
Yin et al.(2017)
PAX3_eDBD_Methyl-HT-SELEX_3		 (Direct) (Direct)
PAX3
M09585_2.00		 Homo sapiens
WSYRTGACWAATBNN
NNVATTWGTCAYRSW		 Misc
Heinz et al.(2010)
Rh4-PAX3_FKHR_GSE19063		 (Direct) (Direct)
PAX3
M10816_2.00		 Homo sapiens
TCGTCACRCHYHM
KDRDGYGTGACGA		 Transfac
Matys et al.(2006)
V$PAX3_01		 (Direct) (Direct)
PAX3
M10817_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX3_B		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
PAX7
M00346_2.00 		Homo sapiens
NGTYAYGSHN
NDSCRTRACN		 PBM
Barrera et al.(2016)
PAX7_REF 		0.944 0.944
PAX7
M00345_2.00 		Homo sapiens
NSGTCACGSN
NSCGTGACSN		 PBM
Barrera et al.(2016)
PAX7_P112L 		0.936 0.936
PAX1
M03442_2.00 		Homo sapiens
DBCANTSAWGCGTGACS
SGTCACGCWTSANTGVH		 SELEX
Jolma et al.(2013)
PAX1_1 		0.752 0.752
PAX9
M03444_2.00 		Homo sapiens
NKCANTSAWGCGTGACS
SGTCACGCWTSANTGMN		 SELEX
Jolma et al.(2013)
PAX9_1 		0.752 0.752
PAX1
M05687_2.00 		Homo sapiens
BCRNTSRWGCGTGACSN
NSGTCACGCWYSANYGV		 SELEX
Yin et al.(2017)
PAX1_eDBD_HT-SELEX 		0.752 0.752
PAX9
M05689_2.00 		Homo sapiens
BHRNYSRDSCGTRACSN
NSGTYACGSHYSRNYDV		 SELEX
Yin et al.(2017)
PAX9_eDBD_HT-SELEX 		0.752 0.752
PAX1
M11207_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX1_B 		0.752 0.752
PAX1
M05688_2.00 		Homo sapiens
BCRNTSAWGCGTGACSN
NSGTCACGCWTSANYGV		 SELEX
Yin et al.(2017)
PAX1_eDBD_Methyl-HT-SELEX 		0.752 0.752
PAX9
M05690_2.00 		Homo sapiens
BCRNTSAWSCGYGACNN
NNGTCRCGSWTSANYGV		 SELEX
Yin et al.(2017)
PAX9_eDBD_Methyl-HT-SELEX 		0.752 0.752
Pax5B
M01301_2.00 		Gallus gallus
NSNDTNNNN
NNNNAHNSN		 PBM
Lambert et al.(2019)
pTH9781 		0.744 0.744
PAX5
M03443_2.00 		Homo sapiens
RNBYANYSAWSCGTRACN
NGTYACGSWTSRNTRVNY		 SELEX
Jolma et al.(2013)
PAX5_1 		0.744 0.744
PAX5
M08160_2.00 		Homo sapiens
RDGCGTGACCNN
NNGGTCACGCHY		 ChIP-seq
Mathelier et al.(2014)
MA0014.3 		0.744 0.744
PAX5
M07995_2.00 		Homo sapiens
BCAVYSRDSCRKRRC
GYYMYGSHYSRBTGV		 ChIP-seq
Gerstein et al.(2012)
GM12878_PAX5C20_HudsonAlpha 		0.744 0.744
PAX5
M07996_2.00 		Homo sapiens
BCASYSRDSCRTRAC
GTYAYGSHYSRSTGV		 ChIP-seq
Gerstein et al.(2012)
GM12878_PAX5N19_HudsonAlpha 		0.744 0.744
PAX5
M07997_2.00 		Homo sapiens
CASYSRDSCRKRACN
NGTYMYGSHYSRSTG		 ChIP-seq
Gerstein et al.(2012)
GM12891_PAX5C20_HudsonAlpha 		0.744 0.744
PAX5
M07998_2.00 		Homo sapiens
BCASYSRDSCGKRRC
GYYMCGSHYSRSTGV		 ChIP-seq
Gerstein et al.(2012)
GM12892_PAX5C20_HudsonAlpha 		0.744 0.744
PAX5
M08227_2.00 		Homo sapiens
BCANYSRDGCGTRAM
KTYACGCHYSRNTGV		 ChIP-seq
Contrino et al.(2012)
Mv108 		0.744 0.744
PAX5
M08228_2.00 		Homo sapiens
AGCGTGRCYG
CRGYCACGCT		 ChIP-seq
Contrino et al.(2012)
Mv109 		0.744 0.744
PAX5
M09341_2.00 		Homo sapiens
SNVDGNKCARCVRAGCRDGAC
GTCHYGCTYBGYTGMNCHBNS		 Misc
Kulakovskiy et al.(2013)
PAX5_HUMAN.H11MO.0.A 		0.744 0.744
Pax5
M09342_2.00 		Mus musculus
VDRNBCAVYVRDSCRKRRM
KYYMYGSHYBRBTGVNYHB		 Misc
Kulakovskiy et al.(2013)
PAX5_MOUSE.H11MO.0.A 		0.744 0.744
PAX5
M09622_2.00 		Homo sapiens
BCASYSRDSCRTGRMN
NKYCAYGSHYSRSTGV		 Misc
Heinz et al.(2010)
GM12878-PAX5_GSE32465_1 		0.744 0.744
Pax7
M00541_2.00 		Mus musculus
NNVATTWN
NWAATBNN		 PBM
Berger et al.(2008)
Pax7_3783 		0.951 0.951
PAX5
M09623_2.00 		Homo sapiens
BCABNVRSCGTGAC
GTCACGSYBNVTGV		 Misc
Heinz et al.(2010)
GM12878-PAX5_GSE32465_2 		0.744 0.744
PAX7
M03292_2.00 		Homo sapiens
WAATYRATTA
TAATYRATTW		 SELEX
Jolma et al.(2013)
PAX7_1 		0.951 0.951
PAX5
M11208_2.00 		Homo sapiens
BCNNNRNKCANBGNWGNRKRGMSRSHNB
VNDSYSKCYMYNCWNCVNTGMNYNNNGV		 Transfac
Matys et al.(2006)
V$PAX5_01 		0.744 0.744
PAX7
M03293_2.00 		Homo sapiens
TAATYGATTA
TAATCRATTA		 SELEX
Jolma et al.(2013)
PAX7_2 		0.951 0.951
PAX5
M11209_2.00 		Homo sapiens
VRHVDGDNDBBTNRAGCGKRACVRYNVH
DBNRYBGTYMCGCTYNAVVHNHCHBDYB		 Transfac
Matys et al.(2006)
V$PAX5_02 		0.744 0.744
PAX7
M05416_2.00 		Homo sapiens
NDSCGTGACGAATYR
YRATTCGTCACGSHN		 SELEX
Yin et al.(2017)
PAX7_eDBD_HT-SELEX_1 		0.951 0.951
PAX5
M11210_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX5_06 		0.744 0.744
PAX7
M05417_2.00 		Homo sapiens
NSGTCACGSHWRTTAN
NTAAYWDSCGTGACSN		 SELEX
Yin et al.(2017)
PAX7_eDBD_HT-SELEX_2 		0.951 0.951
PAX5
M11211_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX5_07 		0.744 0.744
PAX7
M05418_2.00 		Homo sapiens
NNAATCRATTWN
NWAATYGATTNN		 SELEX
Yin et al.(2017)
PAX7_eDBD_HT-SELEX_3 		0.951 0.951
PAX7
M05422_2.00 		Homo sapiens
BVATTMGTCACGSHN
NDSCGTGACKAATBV		 SELEX
Yin et al.(2017)
PAX7_FL_HT-SELEX_1 		0.951 0.951
PAX5
M11212_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX5_Q6 		0.744 0.744
pax9
M11204_2.00 		Danio rerio Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX9_B 		0.744 0.744
PAX7
M05423_2.00 		Homo sapiens
NSGTCACGSYWATTAN
NTAATWRSCGTGACSN		 SELEX
Yin et al.(2017)
PAX7_FL_HT-SELEX_2 		0.951 0.951
pax2
M02428_2.00 		Xenopus tropicalis
NNNRNBCRNN
NNYGVNYNNN		 PBM
Weirauch et al.(2014)
pTH8556 		0.736 0.736
PAX7
M05424_2.00 		Homo sapiens
NTAATYGATTAN
NTAATCRATTAN		 SELEX
Yin et al.(2017)
PAX7_FL_HT-SELEX_3 		0.951 0.951
pax2b
M02425_2.00 		Danio rerio
HVNYSRNSCR
YGSNYSRNBD		 PBM
Weirauch et al.(2014)
pTH8679 		0.728 0.728
PAX7
M05874_2.00 		Homo sapiens
ATTMGTYACGSHN
NDSCGTRACKAAT		 SMiLE-seq
Isakova et al.(2017)
PAX7 		0.951 0.951
Poxm
M03944_2.00 		Drosophila melanogaster
CAVTCAWGCGTGACR
YGTCACGCWTGABTG		 SELEX
Nitta et al.(2015)
Poxm_1 		0.720 0.720
Pax7
M09586_2.00 		Mus musculus
NNNNNYAATTDNNHAATTAN
NTAATTDNNHAATTRNNNNN		 Misc
Heinz et al.(2010)
Myoblast-Pax7_GSE25064_1 		0.951 0.951
Poxm
M03945_2.00 		Drosophila melanogaster
NYSAWGCRTRACS
SGTYAYGCWTSRN		 SELEX
Nitta et al.(2015)
Poxm_2 		0.720 0.720
Pax7
M09587_2.00 		Mus musculus
DTAATYDGATTA
TAATCHRATTAH		 Misc
Heinz et al.(2010)
Myoblast-Pax7_GSE25064_2 		0.951 0.951
PAX8
M05685_2.00 		Homo sapiens
NRNBYRNYSRWGCGTGACSN
NSGTCACGCWYSRNYRVNYN		 SELEX
Yin et al.(2017)
PAX8_FL_HT-SELEX 		0.720 0.720
Pax7
M09588_2.00 		Mus musculus
TAATTGATTW
WAATCAATTA		 Misc
Heinz et al.(2010)
Myoblast-Pax7_GSE25064_3 		0.951 0.951
Poxm
M06436_2.00 		Drosophila melanogaster
NNNNNNMVNHNRNSCRTGA
TCAYGSNYNDNBKNNNNNN		 B1H
Zhu et al.(2011)
Poxm_SOLEXA_5_FBgn0003129 		0.720 0.720
PAX7
M05419_2.00 		Homo sapiens
NVATTVGTCRCGSYN
NRSCGYGACBAATBN		 SELEX
Yin et al.(2017)
PAX7_eDBD_Methyl-HT-SELEX_1 		0.951 0.951
PAX7
M05420_2.00 		Homo sapiens
NNGTCACGSHHRTTAN
NTAAYDDSCGTGACNN		 SELEX
Yin et al.(2017)
PAX7_eDBD_Methyl-HT-SELEX_2 		0.951 0.951
Pax8
M09624_2.00 		Rattus norvegicus
BCAGBCADSCRKGVM
KBCMYGSHTGVCTGV		 Misc
Heinz et al.(2010)
Thyroid-Pax8_GSE26938 		0.720 0.720
PAX8
M11205_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX8_01 		0.720 0.720
PAX7
M05421_2.00 		Homo sapiens
NNAATCRATTWN
NWAATYGATTNN		 SELEX
Yin et al.(2017)
PAX7_eDBD_Methyl-HT-SELEX_3 		0.951 0.951
PAX8
M11206_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX8_B 		0.720 0.720
PAX7
M05425_2.00 		Homo sapiens
YRATTMGTCACGSHN
NDSCGTGACKAATYR		 SELEX
Yin et al.(2017)
PAX7_FL_Methyl-HT-SELEX_1 		0.951 0.951
PAX8
M05686_2.00 		Homo sapiens
NRNBCRNTSAWSCGYGACNN
NNGTCRCGSWTSANYGVNYN		 SELEX
Yin et al.(2017)
PAX8_FL_Methyl-HT-SELEX 		0.720 0.720
PAX7
M05426_2.00 		Homo sapiens
NSGTCACGSYWATTAN
NTAATWRSCGTGACSN		 SELEX
Yin et al.(2017)
PAX7_FL_Methyl-HT-SELEX_2 		0.951 0.951
sv
M01302_2.00 		Drosophila melanogaster
NNNSCRBRDM
KHYVYGSNNN		 PBM
Lambert et al.(2019)
pTH9773 		0.704 0.704
PAX7
M05427_2.00 		Homo sapiens
NTAATYGATTAN
NTAATCRATTAN		 SELEX
Yin et al.(2017)
PAX7_FL_Methyl-HT-SELEX_3 		0.951 0.951
sv
M03949_2.00 		Drosophila melanogaster
NBCRNYSAWGCGTGACS
SGTCACGCWTSRNYGVN		 SELEX
Nitta et al.(2015)
sv_1 		0.704 0.704
prd
M03894_2.00 		Drosophila melanogaster
VATTVGTCACGS
SCGTGACBAATB		 SELEX
Nitta et al.(2015)
prd_1 		0.813 0.813
sv
M06438_2.00 		Drosophila melanogaster
RNYSRDSCGTRACNN
NNGTYACGSHYSRNY		 B1H
Zhu et al.(2011)
sv_SOLEXA_5_FBgn0005561 		0.704 0.704
prd
M03895_2.00 		Drosophila melanogaster
NRATCRATYN
NRATYGATYN		 SELEX
Nitta et al.(2015)
prd_2 		0.813 0.813
prd
M06555_2.00 		Drosophila melanogaster
HSWAACNGH
DCNGTTWSD		 B1H
Mathelier et al.(2014)
MA0239.1 		0.813 0.813
prd
M09684_2.00 		Drosophila melanogaster
HMVNTHHKWMACGS
SCGTKWMDDANBKD		 Misc
Kulakovskiy et al.(2009)
prd 		0.813 0.813
prd
M10818_2.00 		Drosophila melanogaster Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
I$PRD_Q6 		0.813 0.813
gsb-n
M03888_2.00 		Drosophila melanogaster
SCGTRWCKAATB
VATTMGWYACGS		 SELEX
Nitta et al.(2015)
gsb-n_1 		0.791 0.791
gsb
M03889_2.00 		Drosophila melanogaster
RATTMGTCACGSN
NSCGTGACKAATY		 SELEX
Nitta et al.(2015)
gsb_1 		0.769 0.769
gsb
M03890_2.00 		Drosophila melanogaster
NNNAATCRATTWNN
NNWAATYGATTNNN		 SELEX
Nitta et al.(2015)
gsb_2 		0.769 0.769
gsb
M03891_2.00 		Drosophila melanogaster
RTBDMTAATTGATTD
HAATCAATTAKHVAY		 SELEX
Nitta et al.(2015)
gsb_3 		0.769 0.769
gsb
M03892_2.00 		Drosophila melanogaster
NNTAATYGATTANN
NNTAATCRATTANN		 SELEX
Nitta et al.(2015)
gsb_4 		0.769 0.769
gsb
M03893_2.00 		Drosophila melanogaster
NSCGTGACKAATBV
BVATTMGTCACGSN		 SELEX
Nitta et al.(2015)
gsb_5 		0.769 0.769
For this family, TFs with SR scores > 0.700 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00352_2.00 Paired box 16 141
M00352_2.00 Homeodomain 202 258
M00353_2.00 Paired box 16 141
M00353_2.00 Homeodomain 202 258
M00354_2.00 Paired box 16 141
M00354_2.00 Homeodomain 202 258
M00355_2.00 Paired box 16 141
M00355_2.00 Homeodomain 202 258
M00356_2.00 Paired box 16 141
M00356_2.00 Homeodomain 202 258
M00357_2.00 Paired box 16 141
M00357_2.00 Homeodomain 202 258
M00358_2.00 Paired box 16 141
M00358_2.00 Homeodomain 202 258
M00359_2.00 Paired box 16 141
M00359_2.00 Homeodomain 202 258

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000258387 Paired box 34 159
ENSP00000338767 Paired box 34 159
ENSP00000338767 Homeodomain 220 276
ENSP00000342092 Paired box 34 159
ENSP00000342092 Homeodomain 220 276
ENSP00000343052 Paired box 34 159
ENSP00000343052 Homeodomain 220 276
ENSP00000375921 Paired box 34 159
ENSP00000375921 Homeodomain 220 276
ENSP00000375922 Paired box 34 159
ENSP00000375922 Homeodomain 220 276
ENSP00000386750 Paired box 34 158
ENSP00000386750 Homeodomain 219 275
ENSP00000386817 Paired box 34 159

Links

Other Homeodomain,Paired box family TFs
Other Homo sapiens TFs

Invalid Input OrderBy

658 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action