PAX6 (Pan troglodytes)
Homeodomain,Paired box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00292 (PAX)
IPR001356
IPR001523
ENSPTRG00000003474 T237474_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
PAX6
M00342_2.00
Homo sapiens
NNNRCDMATTANNN

NNNTAATKHGYNNN
PBM
Barrera et al.(2016)
PAX6_REF
0.908 0.908
Pax6
M00540_2.00
Mus musculus
CBAATTAA

TTAATTVG
PBM
Berger et al.(2008)
Pax6_3838
0.908 0.908
PAX6
M03291_2.00
Homo sapiens
DTWYACGCWTGANTGMDYH

DRHKCANTCAWGCGTRWAH
SELEX
Jolma et al.(2013)
PAX6_1
0.908 0.908
PAX6
M05412_2.00
Homo sapiens
NYACGCHYSRNYRMNYN

NRNKYRNYSRDGCGTRN
SELEX
Yin et al.(2017)
PAX6_eDBD_HT-SELEX
0.908 0.908
PAX6
M05414_2.00
Homo sapiens
NYRCGCNYSRNYRVNYN

NRNBYRNYSRNGCGYRN
SELEX
Yin et al.(2017)
PAX6_FL_HT-SELEX
0.908 0.908
PAX6
M02689_2.00
Homo sapiens
TTYACGCWTSANTK

MANTSAWGCGTRAA
SELEX
Mathelier et al.(2014)
MA0069.1
0.908 0.908
PAX6
M09216_2.00
Homo sapiens
TYMYRCWTSRNT

ANYSAWGYRKRA
Misc
Kulakovskiy et al.(2013)
PAX6_HUMAN.H11MO.0.C
0.908 0.908
Pax6
M09217_2.00
Mus musculus
TYMYRCWTSRNT

ANYSAWGYRKRA
Misc
Kulakovskiy et al.(2013)
PAX6_MOUSE.H11MO.0.C
0.908 0.908
PAX6
M10806_2.00
Homo sapiens
NHNNTTYACGCWTSANTKVHH

DDBMANTSAWGCGTRAANNDN
Transfac
Matys et al.(2006)
V$PAX6_01
0.908 0.908
PAX6
M10807_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PAX6_Q2
0.908 0.908
PAX6
M00341_2.00
Homo sapiens
BTSCCCSGSC

GSCSGGGSAV
PBM
Barrera et al.(2016)
PAX6_R26G
0.908 0.908
PAX6
M05413_2.00
Homo sapiens
DYRCGCWTSRNYRMNYN

NRNKYRNYSAWGCGYRH
SELEX
Yin et al.(2017)
PAX6_eDBD_Methyl-HT-SELEX
0.908 0.908
PAX6
M05415_2.00
Homo sapiens
NYACGCHYSRNYRMHYN

NRDKYRNYSRDGCGTRN
SELEX
Yin et al.(2017)
PAX6_FL_Methyl-HT-SELEX
0.908 0.908
PAX6
M00335_2.00
Homo sapiens
BRNNNNNN

NNNNNNYV
PBM
Barrera et al.(2016)
PAX6_A79E
0.901 0.901
PAX6
M00336_2.00
Homo sapiens
RTGCACAC

GTGTGCAY
PBM
Barrera et al.(2016)
PAX6_F258S
0.901 0.901
PAX6
M00337_2.00
Homo sapiens
NMTAATTANNN

NNNTAATTAKN
PBM
Barrera et al.(2016)
PAX6_P118R
0.901 0.901
PAX6
M00338_2.00
Homo sapiens
WSGVRVDR

YHBYBCSW
PBM
Barrera et al.(2016)
PAX6_P68S
0.901 0.901
PAX6
M00339_2.00
Homo sapiens
NNNNSGKVGGHNN

NNDCCBMCSNNNN
PBM
Barrera et al.(2016)
PAX6_R128C
0.901 0.901
PAX6
M00340_2.00
Homo sapiens
NNNNNRN

NYNNNNN
PBM
Barrera et al.(2016)
PAX6_R242T
0.901 0.901
PAX6
M00343_2.00
Homo sapiens
NNNNCCCVKCNBN

NVNGMBGGGNNNN
PBM
Barrera et al.(2016)
PAX6_S119R
0.901 0.901
PAX6
M00344_2.00
Homo sapiens
NNMSASGBYNNN

NNNRVCSTSKNN
PBM
Barrera et al.(2016)
PAX6_V126D
0.901 0.901
ey
M03896_2.00
Drosophila melanogaster
CKAATTAD

HTAATTMG
SELEX
Nitta et al.(2015)
ey_1
0.842 0.842
ey
M03897_2.00
Drosophila melanogaster
HTAATCKMATTAD

HTAATKMGATTAD
SELEX
Nitta et al.(2015)
ey_2
0.842 0.842
ey
M03898_2.00
Drosophila melanogaster
WAAYYRRTTN

NAAYYRRTTW
SELEX
Nitta et al.(2015)
ey_3
0.842 0.842
toy
M03899_2.00
Drosophila melanogaster
TTYACGCWTGASTGMACAN

NTGTKCASTCAWGCGTRAA
SELEX
Nitta et al.(2015)
toy_1
0.816 0.816
toy
M03900_2.00
Drosophila melanogaster
NTYACGCWTSAVTGMRCNN

NNGYKCABTSAWGCGTRAN
SELEX
Nitta et al.(2015)
toy_2
0.816 0.816
toy
M03901_2.00
Drosophila melanogaster
VATTANBHAYGSWYSRN

NYSRWSCRTDVNTAATB
SELEX
Nitta et al.(2015)
toy_3
0.816 0.816
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSPTRP00000042753 Paired box 3 97
ENSPTRP00000042753 Homeodomain 180 236

Links

Other Homeodomain,Paired box family TFs
Other Pan troglodytes TFs

143 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ACYPI008177 Acyrthosiphon pisum ACYPI008177 I 0.822
ACYPI067710 Acyrthosiphon pisum ACYPI067710 I 0.842
AAEL002321 Aedes aegypti AAEL002321 I 0.763
ENSAMEG00000006908 Ailuropoda melanoleuca ENSAMEG00000006908 I 0.758
Alligator_sinensis_CCG012954.1 Alligator sinensis Alligator_sinensis_CCG012954.1 I 0.908
ENSAPLG00000004928 Anas platyrhynchos ENSAPLG00000004928 I 0.974
PAX6 Anolis carolinensis ENSACAG00000002252 I 0.908
AALB006643 Anopheles albimanus AALB006643 I 0.750
AARA001110 Anopheles arabiensis AARA001110 I 0.743
ACUA016154 Anopheles culicifacies ACUA016154 I 0.750
ACUA021227 Anopheles culicifacies ACUA021227 I 0.737
AEPI005798 Anopheles epiroticus AEPI005798 I 0.743
AEPI005803 Anopheles epiroticus AEPI005803 I 0.730
AFAF017899 Anopheles farauti AFAF017899 I 0.743
AGAP000067 Anopheles gambiae AGAP000067 I 0.743
AMEC013051 Anopheles melas AMEC013051 I 0.743
AMEM002691 Anopheles merus AMEM002691 I 0.743
AQUA008313 Anopheles quadriannulatus AQUA008313 I 0.743
GB50342 Apis mellifera GB50342 I 0.703
Afo_R014630 Aptenodytes forsteri Afo_R014630 I 0.986
ENSAMXG00000013008 Astyanax mexicanus ENSAMXG00000013008 I 0.742
ENSAMXG00000001228 Astyanax mexicanus ENSAMXG00000001228 I 0.882
ENSP00000368401-D1 Bos grunniens ENSP00000368401-D1 I 0.758
PAX6 Bos taurus ENSBTAG00000004561 I 0.908
fgenesh2_pg.scaffold_199000043 Branchiostoma floridae fgenesh2_pg.scaffold_199000043 I 0.812
fgenesh2_pg.scaffold_23000118 Branchiostoma floridae fgenesh2_pg.scaffold_23000118 I 0.757
BXY_1643500 Bursaphelenchus xylophilus BXY_1643500 I 0.763
vab-3 Caenorhabditis elegans WBGene00006870 I 0.763
CRE07226 Caenorhabditis remanei CRE07226 I 0.770
PAX6 Callithrix jacchus ENSCJAG00000005942 I 0.908
Aan_R006618 Calypte anna Aan_R006618 I 0.974
PAX6 Cavia porcellus ENSCPOG00000007245 I 0.758
Cmyd_10016391 Chelonia mydas Cmyd_10016391 I 0.829
ENSCSAG00000005253 Chlorocebus sabaeus ENSCSAG00000005253 I 0.908
ENSCING00000006503 Ciona intestinalis ENSCING00000006503 I 0.842
ENSCSAVG00000007987 Ciona savignyi ENSCSAVG00000007987 I 0.803
CpipJ_CPIJ006390 Culex pipiens CpipJ_CPIJ006390 I 0.730
CpipJ_CPIJ006398 Culex pipiens CpipJ_CPIJ006398 I 0.737
CPIJ006398 Culex quinquefasciatus CPIJ006398 I 0.737
CPIJ006390 Culex quinquefasciatus CPIJ006390 I 0.730
pax6b Danio rerio ENSDARG00000045936 I 0.901
pax6a Danio rerio ENSDARG00000103379 I 0.901
DAPPUDRAFT_249978 Daphnia pulex DAPPUDRAFT_249978 I 0.836
DAPPUDRAFT_249991 Daphnia pulex DAPPUDRAFT_249991 I 0.829
PAX6 Dasypus novemcinctus ENSDNOG00000000761 I 0.908
GF21877 Drosophila ananassae FBgn0098877 I 0.816
GF22818 Drosophila ananassae FBgn0099812 I 0.709
GG16402 Drosophila erecta FBgn0108634 I 0.816
GG16399 Drosophila erecta FBgn0108631 I 0.842
ey Drosophila melanogaster FBgn0005558 D 0.842
toy Drosophila melanogaster FBgn0019650 D 0.816
GI14081 Drosophila mojavensis FBgn0136835 I 0.849
ey Drosophila persimilis FBgn0043659 I 0.849
ey Drosophila pseudoobscura FBgn0018538 I 0.849
ey Drosophila sechellia FBgn0068720 I 0.842
GM13021 Drosophila sechellia FBgn0167952 I 0.816
GD24416 Drosophila simulans FBgn0195753 I 0.743
ey Drosophila virilis FBgn0028754 I 0.842
GK13702 Drosophila willistoni FBgn0215710 I 0.849
GE14559 Drosophila yakuba FBgn0232158 I 0.842
GE14563 Drosophila yakuba FBgn0232162 I 0.816
PAX6 Echinops telfairi ENSETEG00000002655 I 0.746
PAX6 Equus caballus ENSECAG00000021000 I 0.731
D915_07175 Fasciola hepatica D915_07175 I 0.717
PAX6 Felis catus ENSFCAG00000007094 I 0.758
ENSFALG00000010839 Ficedula albicollis ENSFALG00000010839 I 0.974
ENSGMOG00000019087 Gadus morhua ENSGMOG00000019087 I 0.725
ENSGMOG00000012304 Gadus morhua ENSGMOG00000012304 I 0.901
PAX6 Gallus gallus ENSGALG00000012123 I 0.908
pax6b Gasterosteus aculeatus ENSGACG00000016030 I 0.895
ENSGACG00000002490 Gasterosteus aculeatus ENSGACG00000002490 I 0.868
Gfo_R001537 Geospiza fortis Gfo_R001537 I 0.974
PAX6 Gorilla gorilla ENSGGOG00000010246 I 0.908
Hsal_03768--XP_394294.2_APIME Harpegnathos saltator Hsal_03768--XP_394294.2_APIME I 0.714
PAX6 Homo sapiens ENSG00000007372 D 0.908
ENSSTOG00000003211 Ictidomys tridecemlineatus ENSSTOG00000003211 I 0.908
ISCW021772 Ixodes scapularis ISCW021772 I 0.816
ISCW006352 Ixodes scapularis ISCW006352 I 0.743
ENSLACG00000015337 Latimeria chalumnae ENSLACG00000015337 I 0.901
ENSLOCG00000004578 Lepisosteus oculatus ENSLOCG00000004578 I 0.901
PAX6 Loxodonta africana ENSLAFG00000015520 I 0.758
ENSP00000368424 Macaca fascicularis ENSP00000368424 I 0.758
PAX6 Macaca mulatta ENSMMUG00000016810 I 0.908
MCINX016249 Melitaea cinxia MCINX016249 I 0.704
PAX6 Microcebus murinus ENSMICG00000004089 I 0.908
PAX6 Monodelphis domestica ENSMODG00000009611 I 0.868
ENSMPUG00000011295 Mustela putorius furo ENSMPUG00000011295 I 0.908
Pax6 Mus musculus ENSMUSG00000027168 D 0.908
PAX6 Myotis lucifugus ENSMLUG00000006517 I 0.908
NV15820 Nasonia vitripennis NV15820 I 0.703
ENSNLEG00000017888 Nomascus leucogenys ENSNLEG00000017888 I 0.758
PAX6 Ochotona princeps ENSOPRG00000001678 I 0.908
Ogr12767 Ophisaurus gracilis Ogr12767 I 0.829
ENSONIG00000004074 Oreochromis niloticus ENSONIG00000004074 I 0.882
ENSONIG00000005541 Oreochromis niloticus ENSONIG00000005541 I 0.895
PAX6 Ornithorhynchus anatinus ENSOANG00000015149 I 0.961
PAX6 Oryctolagus cuniculus ENSOCUG00000011075 I 0.758
ENSORLG00000000847 Oryzias latipes ENSORLG00000000847 I 0.875
pax6b Oryzias latipes ENSORLG00000009913 I 0.895
PAX6 Otolemur garnettii ENSOGAG00000007857 I 0.908
ENSOARG00000016191 Ovis aries ENSOARG00000016191 I 0.908
ENSPANG00000005448 Papio anubis ENSPANG00000005448 I 0.908
PTRK_0000512100 Parastrongyloides trichosuri PTRK_0000512100 I 0.750
PHUM097050 Pediculus humanus PHUM097050 I 0.789
ENSPSIG00000012748 Pelodiscus sinensis ENSPSIG00000012748 I 0.908
ENSPFOG00000016987 Poecilia formosa ENSPFOG00000016987 I 0.895
Pvit_09512 Pogona vitticeps Pvit_09512 I 0.908
ENSPPYG00000003386 Pongo abelii ENSPPYG00000003386 I 0.731
PAX6 Procavia capensis ENSPCAG00000005165 I 0.908
Pax6 Rattus norvegicus ENSRNOG00000004410 I 0.908
RSKR_0000862000 Rhabditophanes kr3021 RSKR_0000862000 I 0.776
Sakowv30026828m.g Saccoglossus kowalevskii Sakowv30026828m.g I 0.849
ENSSHAG00000016310 Sarcophilus harrisii ENSSHAG00000016310 I 0.908
A_05170 Schistosoma haematobium A_05170 I 0.750
Smp_170750 Schistosoma mansoni Smp_170750 I 0.737
Smp_160670 Schistosoma mansoni Smp_160670 I 0.757
SMTD_0000837201 Schistosoma mattheei SMTD_0000837201 I 0.750
SMU15027897 Schmidtea mediterranea SMU15027897 I 0.789
SINV20456 Solenopsis invicta SINV20456 I 0.720
PAX6 Sorex araneus ENSSARG00000011424 I 0.746
L596_g12356 Steinernema carpocapsae L596_g12356 I 0.776
L892_g3713 Steinernema scapterisci L892_g3713 I 0.776
SMAR013763 Strigamia maritima SMAR013763 I 0.855
PAX6 Sus scrofa ENSSSCG00000013320 I 0.908
pax6b Takifugu rubripes ENSTRUG00000006935 I 0.888
ENSTRUG00000017375 Takifugu rubripes ENSTRUG00000017375 I 0.725
ENSTSYG00000011965 Tarsius syrichta ENSTSYG00000011965 I 0.978
tetur09g00660 Tetranychus urticae tetur09g00660 I 0.750
pax6b Tetraodon nigroviridis ENSTNIG00000013804 I 0.888
ENSTNIG00000002471 Tetraodon nigroviridis ENSTNIG00000002471 I 0.868
TC007409 Tribolium castaneum TC007409 I 0.829
TC008176 Tribolium castaneum TC008176 I 0.849
EFV57892 Trichinella spiralis EFV57892 I 0.730
TTRE_0000173501 Trichuris trichiura TTRE_0000173501 I 0.803
PAX6 Tupaia belangeri ENSTBEG00000004748 I 0.908
PAX6 Tursiops truncatus ENSTTRG00000002399 I 0.903
pax6.S Xenopus laevis XB-GENE-6464331 I 0.888
pax6.L Xenopus laevis XB-GENE-865046 I 0.895
pax6 Xenopus tropicalis XB-GENE-484088 I 0.908
ENSXMAG00000016421 Xiphophorus maculatus ENSXMAG00000016421 I 0.882
ENSXMAG00000014260 Xiphophorus maculatus ENSXMAG00000014260 I 0.895
L798_11483 Zootermopsis nevadensis L798_11483 I 0.724
L798_00712 Zootermopsis nevadensis L798_00712 I 0.842