GD24416 (Drosophila simulans)
Homeodomain,Paired box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00292 (PAX)
IPR001356
IPR001523
FBgn0195753 T237592_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
toy
M03899_2.00
Drosophila melanogaster
TTYACGCWTGASTGMACAN

NTGTKCASTCAWGCGTRAA
SELEX
Nitta et al.(2015)
toy_1
1.000 1.000
toy
M03900_2.00
Drosophila melanogaster
NTYACGCWTSAVTGMRCNN

NNGYKCABTSAWGCGTRAN
SELEX
Nitta et al.(2015)
toy_2
1.000 1.000
toy
M03901_2.00
Drosophila melanogaster
VATTANBHAYGSWYSRN

NYSRWSCRTDVNTAATB
SELEX
Nitta et al.(2015)
toy_3
1.000 1.000
ey
M03896_2.00
Drosophila melanogaster
CKAATTAD

HTAATTMG
SELEX
Nitta et al.(2015)
ey_1
0.906 0.906
ey
M03897_2.00
Drosophila melanogaster
HTAATCKMATTAD

HTAATKMGATTAD
SELEX
Nitta et al.(2015)
ey_2
0.906 0.906
ey
M03898_2.00
Drosophila melanogaster
WAAYYRRTTN

NAAYYRRTTW
SELEX
Nitta et al.(2015)
ey_3
0.906 0.906
PAX6
M00342_2.00
Homo sapiens
NNNRCDMATTANNN

NNNTAATKHGYNNN
PBM
Barrera et al.(2016)
PAX6_REF
0.901 0.901
Pax6
M00540_2.00
Mus musculus
CBAATTAA

TTAATTVG
PBM
Berger et al.(2008)
Pax6_3838
0.901 0.901
PAX6
M03291_2.00
Homo sapiens
DTWYACGCWTGANTGMDYH

DRHKCANTCAWGCGTRWAH
SELEX
Jolma et al.(2013)
PAX6_1
0.901 0.901
PAX6
M05412_2.00
Homo sapiens
NYACGCHYSRNYRMNYN

NRNKYRNYSRDGCGTRN
SELEX
Yin et al.(2017)
PAX6_eDBD_HT-SELEX
0.901 0.901
PAX6
M05414_2.00
Homo sapiens
NYRCGCNYSRNYRVNYN

NRNBYRNYSRNGCGYRN
SELEX
Yin et al.(2017)
PAX6_FL_HT-SELEX
0.901 0.901
PAX6
M02689_2.00
Homo sapiens
TTYACGCWTSANTK

MANTSAWGCGTRAA
SELEX
Mathelier et al.(2014)
MA0069.1
0.901 0.901
PAX6
M09216_2.00
Homo sapiens
TYMYRCWTSRNT

ANYSAWGYRKRA
Misc
Kulakovskiy et al.(2013)
PAX6_HUMAN.H11MO.0.C
0.901 0.901
Pax6
M09217_2.00
Mus musculus
TYMYRCWTSRNT

ANYSAWGYRKRA
Misc
Kulakovskiy et al.(2013)
PAX6_MOUSE.H11MO.0.C
0.901 0.901
PAX6
M10806_2.00
Homo sapiens
NHNNTTYACGCWTSANTKVHH

DDBMANTSAWGCGTRAANNDN
Transfac
Matys et al.(2006)
V$PAX6_01
0.901 0.901
PAX6
M10807_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PAX6_Q2
0.901 0.901
PAX6
M00336_2.00
Homo sapiens
RTGCACAC

GTGTGCAY
PBM
Barrera et al.(2016)
PAX6_F258S
0.901 0.901
PAX6
M05413_2.00
Homo sapiens
DYRCGCWTSRNYRMNYN

NRNKYRNYSAWGCGYRH
SELEX
Yin et al.(2017)
PAX6_eDBD_Methyl-HT-SELEX
0.901 0.901
PAX6
M05415_2.00
Homo sapiens
NYACGCHYSRNYRMHYN

NRDKYRNYSRDGCGTRN
SELEX
Yin et al.(2017)
PAX6_FL_Methyl-HT-SELEX
0.901 0.901
PAX6
M00335_2.00
Homo sapiens
BRNNNNNN

NNNNNNYV
PBM
Barrera et al.(2016)
PAX6_A79E
0.895 0.895
PAX6
M00337_2.00
Homo sapiens
NMTAATTANNN

NNNTAATTAKN
PBM
Barrera et al.(2016)
PAX6_P118R
0.895 0.895
PAX6
M00338_2.00
Homo sapiens
WSGVRVDR

YHBYBCSW
PBM
Barrera et al.(2016)
PAX6_P68S
0.895 0.895
PAX6
M00339_2.00
Homo sapiens
NNNNSGKVGGHNN

NNDCCBMCSNNNN
PBM
Barrera et al.(2016)
PAX6_R128C
0.895 0.895
PAX6
M00340_2.00
Homo sapiens
NNNNNRN

NYNNNNN
PBM
Barrera et al.(2016)
PAX6_R242T
0.895 0.895
PAX6
M00341_2.00
Homo sapiens
BTSCCCSGSC

GSCSGGGSAV
PBM
Barrera et al.(2016)
PAX6_R26G
0.895 0.895
PAX6
M00343_2.00
Homo sapiens
NNNNCCCVKCNBN

NVNGMBGGGNNNN
PBM
Barrera et al.(2016)
PAX6_S119R
0.895 0.895
PAX6
M00344_2.00
Homo sapiens
NNMSASGBYNNN

NNNRVCSTSKNN
PBM
Barrera et al.(2016)
PAX6_V126D
0.895 0.895
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0222818 Paired box 29 153
FBpp0222818 Homeodomain 266 311

Links

Other Homeodomain,Paired box family TFs
Other Drosophila simulans TFs

185 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
GG16402 Drosophila erecta FBgn0108634 I 1.000
GE14563 Drosophila yakuba FBgn0232162 I 1.000
toy Drosophila melanogaster FBgn0019650 D 1.000
GM13021 Drosophila sechellia FBgn0167952 I 1.000
GF21877 Drosophila ananassae FBgn0098877 I 0.988
L798_00712 Zootermopsis nevadensis L798_00712 I 0.953
TC007409 Tribolium castaneum TC007409 I 0.953
DAPPUDRAFT_249978 Daphnia pulex DAPPUDRAFT_249978 I 0.942
ACYPI008177 Acyrthosiphon pisum ACYPI008177 I 0.942
GH23963 Drosophila grimshawi FBgn0131420 I 0.929
GJ13300 Drosophila virilis FBgn0200526 I 0.929
GA27636 Drosophila pseudoobscura FBgn0249001 I 0.929
GL17563 Drosophila persimilis FBgn0155166 I 0.929
GI14042 Drosophila mojavensis FBgn0136796 I 0.929
GK13683 Drosophila willistoni FBgn0215691 I 0.929
SMAR013763 Strigamia maritima SMAR013763 I 0.924
ENSGACG00000002490 Gasterosteus aculeatus ENSGACG00000002490 I 0.912
ADAC001560 Anopheles darlingi ADAC001560 I 0.910
NV17076 Nasonia vitripennis NV17076 I 0.907
Cflo_00481--XP_394648.3_APIME Camponotus floridanus Cflo_00481--XP_394648.3_APIME I 0.907
Hsal_09597--XP_394648.3_APIME Harpegnathos saltator Hsal_09597--XP_394648.3_APIME I 0.907
GB41504 Apis mellifera GB41504 I 0.907
ey Drosophila melanogaster FBgn0005558 D 0.906
TC008176 Tribolium castaneum TC008176 I 0.906
AEPI005798 Anopheles epiroticus AEPI005798 I 0.906
AFAF017899 Anopheles farauti AFAF017899 I 0.906
AFUN011570 Anopheles funestus AFUN011570 I 0.906
PHUM097050 Pediculus humanus PHUM097050 I 0.906
ADIR000973 Anopheles dirus ADIR000973 I 0.906
ACUA016154 Anopheles culicifacies ACUA016154 I 0.906
AGAP000067 Anopheles gambiae AGAP000067 I 0.906
AALB006643 Anopheles albimanus AALB006643 I 0.906
AARA001110 Anopheles arabiensis AARA001110 I 0.906
AATE014626 Anopheles atroparvus AATE014626 I 0.906
ACHR009845 Anopheles christyi ACHR009845 I 0.906
ey Drosophila persimilis FBgn0043659 I 0.906
ey Drosophila pseudoobscura FBgn0018538 I 0.906
GI14081 Drosophila mojavensis FBgn0136835 I 0.906
AQUA008313 Anopheles quadriannulatus AQUA008313 I 0.906
pax6a Danio rerio ENSDARG00000103379 I 0.906
ACYPI067710 Acyrthosiphon pisum ACYPI067710 I 0.906
GK13702 Drosophila willistoni FBgn0215710 I 0.906
ASTEI06205 Anopheles stephensi ASTEI06205 I 0.906
AMIN002132 Anopheles minimus AMIN002132 I 0.906
AMEM002691 Anopheles merus AMEM002691 I 0.906
CPIJ006398 Culex quinquefasciatus CPIJ006398 I 0.906
AMEC013051 Anopheles melas AMEC013051 I 0.906
CpipJ_CPIJ006398 Culex pipiens CpipJ_CPIJ006398 I 0.906
Pax6 Rattus norvegicus ENSRNOG00000004410 I 0.901
ENSSTOG00000003211 Ictidomys tridecemlineatus ENSSTOG00000003211 I 0.901
Sakowv30026828m.g Saccoglossus kowalevskii Sakowv30026828m.g I 0.901
ENSSHAG00000016310 Sarcophilus harrisii ENSSHAG00000016310 I 0.901
PAX6 Sus scrofa ENSSSCG00000013320 I 0.901
PAX6 Anolis carolinensis ENSACAG00000002252 I 0.901
ENSXMAG00000014260 Xiphophorus maculatus ENSXMAG00000014260 I 0.901
pax6 Xenopus tropicalis XB-GENE-484088 I 0.901
ey Drosophila virilis FBgn0028754 I 0.901
GG16399 Drosophila erecta FBgn0108631 I 0.901
Alligator_sinensis_CCG012954.1 Alligator sinensis Alligator_sinensis_CCG012954.1 I 0.901
GE14559 Drosophila yakuba FBgn0232158 I 0.901
Pvit_09512 Pogona vitticeps Pvit_09512 I 0.901
ey Drosophila sechellia FBgn0068720 I 0.901
PAX6 Tupaia belangeri ENSTBEG00000004748 I 0.901
PAX6 Ochotona princeps ENSOPRG00000001678 I 0.901
ENSGMOG00000012304 Gadus morhua ENSGMOG00000012304 I 0.901
PAX6 Gorilla gorilla ENSGGOG00000010246 I 0.901
ENSLACG00000015337 Latimeria chalumnae ENSLACG00000015337 I 0.901
ENSLOCG00000004578 Lepisosteus oculatus ENSLOCG00000004578 I 0.901
PAX6 Microcebus murinus ENSMICG00000004089 I 0.901
PAX6 Gallus gallus ENSGALG00000012123 I 0.901
PAX6 Bos taurus ENSBTAG00000004561 I 0.901
ENSCSAG00000005253 Chlorocebus sabaeus ENSCSAG00000005253 I 0.901
PAX6 Callithrix jacchus ENSCJAG00000005942 I 0.901
pax6b Danio rerio ENSDARG00000045936 I 0.901
PAX6 Dasypus novemcinctus ENSDNOG00000000761 I 0.901
PAX6 Homo sapiens ENSG00000007372 D 0.901
ENSPSIG00000012748 Pelodiscus sinensis ENSPSIG00000012748 I 0.901
PAX6 Myotis lucifugus ENSMLUG00000006517 I 0.901
PAX6 Macaca mulatta ENSMMUG00000016810 I 0.901
pax6b Oryzias latipes ENSORLG00000009913 I 0.901
ENSPANG00000005448 Papio anubis ENSPANG00000005448 I 0.901
PAX6 Procavia capensis ENSPCAG00000005165 I 0.901
ENSOARG00000016191 Ovis aries ENSOARG00000016191 I 0.901
PAX6 Otolemur garnettii ENSOGAG00000007857 I 0.901
Pax6 Mus musculus ENSMUSG00000027168 D 0.901
ENSMPUG00000011295 Mustela putorius furo ENSMPUG00000011295 I 0.901
pax6.S Xenopus laevis XB-GENE-6464331 I 0.895
TTRE_0000173501 Trichuris trichiura TTRE_0000173501 I 0.895
pax6.L Xenopus laevis XB-GENE-865046 I 0.895
Ogr12767 Ophisaurus gracilis Ogr12767 I 0.895
Cmyd_10016391 Chelonia mydas Cmyd_10016391 I 0.895
ISCW006352 Ixodes scapularis ISCW006352 I 0.895
ENSXMAG00000016421 Xiphophorus maculatus ENSXMAG00000016421 I 0.895
pax6b Takifugu rubripes ENSTRUG00000006935 I 0.895
ENSPFOG00000016987 Poecilia formosa ENSPFOG00000016987 I 0.895
ENSONIG00000005541 Oreochromis niloticus ENSONIG00000005541 I 0.895
pax6b Gasterosteus aculeatus ENSGACG00000016030 I 0.895
pax6b Tetraodon nigroviridis ENSTNIG00000013804 I 0.895
ENSPPYG00000003386 Pongo abelii ENSPPYG00000003386 I 0.892
ENSAMXG00000001228 Astyanax mexicanus ENSAMXG00000001228 I 0.889
SMU15027897 Schmidtea mediterranea SMU15027897 I 0.889
ENSONIG00000004074 Oreochromis niloticus ENSONIG00000004074 I 0.889
DAPPUDRAFT_249991 Daphnia pulex DAPPUDRAFT_249991 I 0.889
ENSORLG00000000847 Oryzias latipes ENSORLG00000000847 I 0.883
ENSTNIG00000002471 Tetraodon nigroviridis ENSTNIG00000002471 I 0.877
ISCW021772 Ixodes scapularis ISCW021772 I 0.871
PAX6 Monodelphis domestica ENSMODG00000009611 I 0.866
MCINX016249 Melitaea cinxia MCINX016249 I 0.866
ASIS012617 Anopheles sinensis ASIS012617 I 0.856
L798_11483 Zootermopsis nevadensis L798_11483 I 0.856
ENSCING00000006503 Ciona intestinalis ENSCING00000006503 I 0.854
GB50342 Apis mellifera GB50342 I 0.852
ENSP00000368424 Macaca fascicularis ENSP00000368424 I 0.852
PAX6 Cavia porcellus ENSCPOG00000007245 I 0.852
ENSAMEG00000006908 Ailuropoda melanoleuca ENSAMEG00000006908 I 0.852
ENSP00000368401-D1 Bos grunniens ENSP00000368401-D1 I 0.852
ENSNLEG00000017888 Nomascus leucogenys ENSNLEG00000017888 I 0.852
PAX6 Oryctolagus cuniculus ENSOCUG00000011075 I 0.852
PAX6 Felis catus ENSFCAG00000007094 I 0.852
NV15820 Nasonia vitripennis NV15820 I 0.852
PAX6 Loxodonta africana ENSLAFG00000015520 I 0.852
GF22818 Drosophila ananassae FBgn0099812 I 0.846
D918_01592 Trichuris suis D918_01592 I 0.846
L596_g12356 Steinernema carpocapsae L596_g12356 I 0.842
L892_g3713 Steinernema scapterisci L892_g3713 I 0.842
TMUE_s0038005250 Trichuris muris TMUE_s0038005250 I 0.841
ENSAMXG00000013008 Astyanax mexicanus ENSAMXG00000013008 I 0.841
PAX6 Sorex araneus ENSSARG00000011424 I 0.838
ENSGMOG00000019087 Gadus morhua ENSGMOG00000019087 I 0.835
ENSTRUG00000017375 Takifugu rubripes ENSTRUG00000017375 I 0.830
PAX6 Echinops telfairi ENSETEG00000002655 I 0.827
PTRK_0000512100 Parastrongyloides trichosuri PTRK_0000512100 I 0.825
PAX6 Equus caballus ENSECAG00000021000 I 0.824
CRE07226 Caenorhabditis remanei CRE07226 I 0.819
LotgiG133720 Lottia gigantea LotgiG133720 I 0.819
CGI_10027695 Crassostrea gigas CGI_10027695 I 0.819
Smp_160670 Schistosoma mansoni Smp_160670 I 0.819
EFV57892 Trichinella spiralis EFV57892 I 0.819
D917_00854 Trichinella nativa D917_00854 I 0.817
csin101119 Clonorchis sinensis csin101119 I 0.815
RSKR_0000862000 Rhabditophanes kr3021 RSKR_0000862000 I 0.813
AAEL002321 Aedes aegypti AAEL002321 I 0.813
SMTD_0000837201 Schistosoma mattheei SMTD_0000837201 I 0.807
ADAC003449 Anopheles darlingi ADAC003449 I 0.807
AFAF009619 Anopheles farauti AFAF009619 I 0.807
A_05170 Schistosoma haematobium A_05170 I 0.807
vab-3 Caenorhabditis elegans WBGene00006870 I 0.807
ENSCSAVG00000007987 Ciona savignyi ENSCSAVG00000007987 I 0.802
ACHR008920 Anopheles christyi ACHR008920 I 0.801
HelroG173449 Helobdella robusta HelroG173449 I 0.795
tetur09g00660 Tetranychus urticae tetur09g00660 I 0.789
LLOJ005149 Lutzomyia longipalpis LLOJ005149 I 0.789
HelroG80374 Helobdella robusta HelroG80374 I 0.786
Smp_170750 Schistosoma mansoni Smp_170750 I 0.778
BXY_1643500 Bursaphelenchus xylophilus BXY_1643500 I 0.772
ACUA021227 Anopheles culicifacies ACUA021227 I 0.772
D915_07175 Fasciola hepatica D915_07175 I 0.772
T265_09221 Opisthorchis viverrini T265_09221 I 0.769
CBN04513 Caenorhabditis brenneri CBN04513 I 0.769
MESCA003564 Megaselia scalaris MESCA003564 I 0.769
AEPI005803 Anopheles epiroticus AEPI005803 I 0.766
CpipJ_CPIJ006390 Culex pipiens CpipJ_CPIJ006390 I 0.760
CPIJ006390 Culex quinquefasciatus CPIJ006390 I 0.760
SPAL_0001466800 Strongyloides papillosus SPAL_0001466800 I 0.758
AARA001115 Anopheles arabiensis AARA001115 I 0.758
SSTP_0001059400 Strongyloides stercoralis SSTP_0001059400 I 0.758
AALB006354 Anopheles albimanus AALB006354 I 0.758
SVE_0819200 Strongyloides venezuelensis SVE_0819200 I 0.758
AGAP000063 Anopheles gambiae AGAP000063 I 0.758
ASIS012967 Anopheles sinensis ASIS012967 I 0.758
AQUA008308 Anopheles quadriannulatus AQUA008308 I 0.758
AMIN002127 Anopheles minimus AMIN002127 I 0.758
ASTEI06200 Anopheles stephensi ASTEI06200 I 0.758
csin110224 Clonorchis sinensis csin110224 I 0.754
AFUN011575 Anopheles funestus AFUN011575 I 0.753
AMEC021831 Anopheles melas AMEC021831 I 0.753
ADIR000968 Anopheles dirus ADIR000968 I 0.743
PAX6 Pan troglodytes ENSPTRG00000003474 I 0.743
ENSMEUG00000015900 Macropus eugenii ENSMEUG00000015900 I 0.743
Afo_R014630 Aptenodytes forsteri Afo_R014630 I 0.741
ENSTSYG00000011965 Tarsius syrichta ENSTSYG00000011965 I 0.739
T265_14971 Opisthorchis viverrini T265_14971 I 0.738
MCOS_0000220101 Mesocestoides corti MCOS_0000220101 I 0.736
TsM_000166900 Taenia solium TsM_000166900 I 0.731
TTAC_0000231001 Hydatigera taeniaeformis TTAC_0000231001 I 0.719