Smp_170750 (Schistosoma mansoni)
Homeodomain,Paired box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00292 (PAX)
IPR001356
IPR001523
Smp_170750 T237664_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
PAX6
M00342_2.00
Homo sapiens
NNNRCDMATTANNN

NNNTAATKHGYNNN
PBM
Barrera et al.(2016)
PAX6_REF
0.830 0.830
Pax6
M00540_2.00
Mus musculus
CBAATTAA

TTAATTVG
PBM
Berger et al.(2008)
Pax6_3838
0.830 0.830
PAX6
M03291_2.00
Homo sapiens
DTWYACGCWTGANTGMDYH

DRHKCANTCAWGCGTRWAH
SELEX
Jolma et al.(2013)
PAX6_1
0.830 0.830
PAX6
M05412_2.00
Homo sapiens
NYACGCHYSRNYRMNYN

NRNKYRNYSRDGCGTRN
SELEX
Yin et al.(2017)
PAX6_eDBD_HT-SELEX
0.830 0.830
PAX6
M05414_2.00
Homo sapiens
NYRCGCNYSRNYRVNYN

NRNBYRNYSRNGCGYRN
SELEX
Yin et al.(2017)
PAX6_FL_HT-SELEX
0.830 0.830
PAX6
M02689_2.00
Homo sapiens
TTYACGCWTSANTK

MANTSAWGCGTRAA
SELEX
Mathelier et al.(2014)
MA0069.1
0.830 0.830
PAX6
M09216_2.00
Homo sapiens
TYMYRCWTSRNT

ANYSAWGYRKRA
Misc
Kulakovskiy et al.(2013)
PAX6_HUMAN.H11MO.0.C
0.830 0.830
Pax6
M09217_2.00
Mus musculus
TYMYRCWTSRNT

ANYSAWGYRKRA
Misc
Kulakovskiy et al.(2013)
PAX6_MOUSE.H11MO.0.C
0.830 0.830
PAX6
M10806_2.00
Homo sapiens
NHNNTTYACGCWTSANTKVHH

DDBMANTSAWGCGTRAANNDN
Transfac
Matys et al.(2006)
V$PAX6_01
0.830 0.830
PAX6
M10807_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PAX6_Q2
0.830 0.830
PAX6
M00340_2.00
Homo sapiens
NNNNNRN

NYNNNNN
PBM
Barrera et al.(2016)
PAX6_R242T
0.830 0.830
PAX6
M05413_2.00
Homo sapiens
DYRCGCWTSRNYRMNYN

NRNKYRNYSAWGCGYRH
SELEX
Yin et al.(2017)
PAX6_eDBD_Methyl-HT-SELEX
0.830 0.830
PAX6
M05415_2.00
Homo sapiens
NYACGCHYSRNYRMHYN

NRDKYRNYSRDGCGTRN
SELEX
Yin et al.(2017)
PAX6_FL_Methyl-HT-SELEX
0.830 0.830
PAX6
M00335_2.00
Homo sapiens
BRNNNNNN

NNNNNNYV
PBM
Barrera et al.(2016)
PAX6_A79E
0.824 0.824
PAX6
M00336_2.00
Homo sapiens
RTGCACAC

GTGTGCAY
PBM
Barrera et al.(2016)
PAX6_F258S
0.824 0.824
PAX6
M00337_2.00
Homo sapiens
NMTAATTANNN

NNNTAATTAKN
PBM
Barrera et al.(2016)
PAX6_P118R
0.824 0.824
PAX6
M00338_2.00
Homo sapiens
WSGVRVDR

YHBYBCSW
PBM
Barrera et al.(2016)
PAX6_P68S
0.824 0.824
PAX6
M00339_2.00
Homo sapiens
NNNNSGKVGGHNN

NNDCCBMCSNNNN
PBM
Barrera et al.(2016)
PAX6_R128C
0.824 0.824
PAX6
M00341_2.00
Homo sapiens
BTSCCCSGSC

GSCSGGGSAV
PBM
Barrera et al.(2016)
PAX6_R26G
0.824 0.824
PAX6
M00343_2.00
Homo sapiens
NNNNCCCVKCNBN

NVNGMBGGGNNNN
PBM
Barrera et al.(2016)
PAX6_S119R
0.824 0.824
PAX6
M00344_2.00
Homo sapiens
NNMSASGBYNNN

NNNRVCSTSKNN
PBM
Barrera et al.(2016)
PAX6_V126D
0.824 0.824
ey
M03896_2.00
Drosophila melanogaster
CKAATTAD

HTAATTMG
SELEX
Nitta et al.(2015)
ey_1
0.808 0.808
ey
M03897_2.00
Drosophila melanogaster
HTAATCKMATTAD

HTAATKMGATTAD
SELEX
Nitta et al.(2015)
ey_2
0.808 0.808
ey
M03898_2.00
Drosophila melanogaster
WAAYYRRTTN

NAAYYRRTTW
SELEX
Nitta et al.(2015)
ey_3
0.808 0.808
toy
M03899_2.00
Drosophila melanogaster
TTYACGCWTGASTGMACAN

NTGTKCASTCAWGCGTRAA
SELEX
Nitta et al.(2015)
toy_1
0.791 0.791
toy
M03900_2.00
Drosophila melanogaster
NTYACGCWTSAVTGMRCNN

NNGYKCABTSAWGCGTRAN
SELEX
Nitta et al.(2015)
toy_2
0.791 0.791
toy
M03901_2.00
Drosophila melanogaster
VATTANBHAYGSWYSRN

NYSRWSCRTDVNTAATB
SELEX
Nitta et al.(2015)
toy_3
0.791 0.791
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
Smp_170750.1:pep Paired box 8 132
Smp_170750.1:pep Homeodomain 761 817

Links

Other Homeodomain,Paired box family TFs
Other Schistosoma mansoni TFs

186 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
T265_09221 Opisthorchis viverrini T265_09221 I 0.907
csin101119 Clonorchis sinensis csin101119 I 0.892
csin110224 Clonorchis sinensis csin110224 I 0.874
SMTD_0000837201 Schistosoma mattheei SMTD_0000837201 I 0.852
A_05170 Schistosoma haematobium A_05170 I 0.852
Smp_160670 Schistosoma mansoni Smp_160670 I 0.852
ENSGMOG00000019087 Gadus morhua ENSGMOG00000019087 I 0.841
pax6b Tetraodon nigroviridis ENSTNIG00000013804 I 0.835
pax6b Gasterosteus aculeatus ENSGACG00000016030 I 0.835
pax6b Oryzias latipes ENSORLG00000009913 I 0.835
ENSPFOG00000016987 Poecilia formosa ENSPFOG00000016987 I 0.835
ENSONIG00000005541 Oreochromis niloticus ENSONIG00000005541 I 0.835
pax6b Takifugu rubripes ENSTRUG00000006935 I 0.835
ENSXMAG00000014260 Xiphophorus maculatus ENSXMAG00000014260 I 0.835
T265_14971 Opisthorchis viverrini T265_14971 I 0.835
pax6.S Xenopus laevis XB-GENE-6464331 I 0.835
PAX6 Microcebus murinus ENSMICG00000004089 I 0.830
PAX6 Oryctolagus cuniculus ENSOCUG00000011075 I 0.830
PAX6 Otolemur garnettii ENSOGAG00000007857 I 0.830
ENSOARG00000016191 Ovis aries ENSOARG00000016191 I 0.830
ENSLOCG00000004578 Lepisosteus oculatus ENSLOCG00000004578 I 0.830
ENSNLEG00000017888 Nomascus leucogenys ENSNLEG00000017888 I 0.830
PAX6 Macaca mulatta ENSMMUG00000016810 I 0.830
ENSMPUG00000011295 Mustela putorius furo ENSMPUG00000011295 I 0.830
Pax6 Mus musculus ENSMUSG00000027168 D 0.830
PAX6 Myotis lucifugus ENSMLUG00000006517 I 0.830
Pax6 Rattus norvegicus ENSRNOG00000004410 I 0.830
pax6 Xenopus tropicalis XB-GENE-484088 I 0.830
PAX6 Tupaia belangeri ENSTBEG00000004748 I 0.830
SMU15027897 Schmidtea mediterranea SMU15027897 I 0.830
Pvit_09512 Pogona vitticeps Pvit_09512 I 0.830
ENSP00000368401-D1 Bos grunniens ENSP00000368401-D1 I 0.830
ENSP00000368424 Macaca fascicularis ENSP00000368424 I 0.830
ENSSTOG00000003211 Ictidomys tridecemlineatus ENSSTOG00000003211 I 0.830
PAX6 Sus scrofa ENSSSCG00000013320 I 0.830
PAX6 Procavia capensis ENSPCAG00000005165 I 0.830
Alligator_sinensis_CCG012954.1 Alligator sinensis Alligator_sinensis_CCG012954.1 I 0.830
ENSPSIG00000012748 Pelodiscus sinensis ENSPSIG00000012748 I 0.830
PAX6 Loxodonta africana ENSLAFG00000015520 I 0.830
ENSSHAG00000016310 Sarcophilus harrisii ENSSHAG00000016310 I 0.830
PAX6 Ochotona princeps ENSOPRG00000001678 I 0.830
ENSPANG00000005448 Papio anubis ENSPANG00000005448 I 0.830
PAX6 Callithrix jacchus ENSCJAG00000005942 I 0.830
PAX6 Cavia porcellus ENSCPOG00000007245 I 0.830
ENSCSAG00000005253 Chlorocebus sabaeus ENSCSAG00000005253 I 0.830
pax6b Danio rerio ENSDARG00000045936 I 0.830
PAX6 Bos taurus ENSBTAG00000004561 I 0.830
ENSAMXG00000013008 Astyanax mexicanus ENSAMXG00000013008 I 0.830
ENSLACG00000015337 Latimeria chalumnae ENSLACG00000015337 I 0.830
PAX6 Anolis carolinensis ENSACAG00000002252 I 0.830
ENSAMEG00000006908 Ailuropoda melanoleuca ENSAMEG00000006908 I 0.830
pax6a Danio rerio ENSDARG00000103379 I 0.830
ENSAMXG00000001228 Astyanax mexicanus ENSAMXG00000001228 I 0.830
PAX6 Gorilla gorilla ENSGGOG00000010246 I 0.830
PAX6 Dasypus novemcinctus ENSDNOG00000000761 I 0.830
PAX6 Gallus gallus ENSGALG00000012123 I 0.830
PAX6 Felis catus ENSFCAG00000007094 I 0.830
PAX6 Homo sapiens ENSG00000007372 D 0.830
ENSGMOG00000012304 Gadus morhua ENSGMOG00000012304 I 0.830
ENSXMAG00000016421 Xiphophorus maculatus ENSXMAG00000016421 I 0.824
ENSONIG00000004074 Oreochromis niloticus ENSONIG00000004074 I 0.824
pax6.L Xenopus laevis XB-GENE-865046 I 0.824
L798_11483 Zootermopsis nevadensis L798_11483 I 0.823
PAX6 Sorex araneus ENSSARG00000011424 I 0.821
DAPPUDRAFT_249991 Daphnia pulex DAPPUDRAFT_249991 I 0.819
ENSGACG00000002490 Gasterosteus aculeatus ENSGACG00000002490 I 0.819
Sakowv30026828m.g Saccoglossus kowalevskii Sakowv30026828m.g I 0.819
ENSTRUG00000017375 Takifugu rubripes ENSTRUG00000017375 I 0.819
Cmyd_10016391 Chelonia mydas Cmyd_10016391 I 0.818
PHUM097050 Pediculus humanus PHUM097050 I 0.814
Ogr12767 Ophisaurus gracilis Ogr12767 I 0.813
TTRE_0000173501 Trichuris trichiura TTRE_0000173501 I 0.813
GB41504 Apis mellifera GB41504 I 0.813
GF22818 Drosophila ananassae FBgn0099812 I 0.813
ey Drosophila pseudoobscura FBgn0018538 I 0.813
ey Drosophila persimilis FBgn0043659 I 0.813
L798_00712 Zootermopsis nevadensis L798_00712 I 0.813
Hsal_09597--XP_394648.3_APIME Harpegnathos saltator Hsal_09597--XP_394648.3_APIME I 0.813
TMUE_s0038005250 Trichuris muris TMUE_s0038005250 I 0.813
Cflo_00481--XP_394648.3_APIME Camponotus floridanus Cflo_00481--XP_394648.3_APIME I 0.813
ENSORLG00000000847 Oryzias latipes ENSORLG00000000847 I 0.813
NV17076 Nasonia vitripennis NV17076 I 0.813
SMAR013763 Strigamia maritima SMAR013763 I 0.813
TC008176 Tribolium castaneum TC008176 I 0.813
DAPPUDRAFT_249978 Daphnia pulex DAPPUDRAFT_249978 I 0.813
GK13702 Drosophila willistoni FBgn0215710 I 0.813
GI14081 Drosophila mojavensis FBgn0136835 I 0.813
D918_01592 Trichuris suis D918_01592 I 0.813
PAX6 Echinops telfairi ENSETEG00000002655 I 0.809
GE14559 Drosophila yakuba FBgn0232158 I 0.808
LotgiG133720 Lottia gigantea LotgiG133720 I 0.808
NV15820 Nasonia vitripennis NV15820 I 0.808
ACYPI067710 Acyrthosiphon pisum ACYPI067710 I 0.808
GB50342 Apis mellifera GB50342 I 0.808
ey Drosophila melanogaster FBgn0005558 D 0.808
ey Drosophila virilis FBgn0028754 I 0.808
ENSPPYG00000003386 Pongo abelii ENSPPYG00000003386 I 0.808
GG16399 Drosophila erecta FBgn0108631 I 0.808
ey Drosophila sechellia FBgn0068720 I 0.808
D915_07175 Fasciola hepatica D915_07175 I 0.802
TC007409 Tribolium castaneum TC007409 I 0.802
GJ13300 Drosophila virilis FBgn0200526 I 0.802
ENSCING00000006503 Ciona intestinalis ENSCING00000006503 I 0.802
PAX6 Equus caballus ENSECAG00000021000 I 0.802
ACYPI008177 Acyrthosiphon pisum ACYPI008177 I 0.802
GA27636 Drosophila pseudoobscura FBgn0249001 I 0.802
CGI_10027695 Crassostrea gigas CGI_10027695 I 0.802
GH23963 Drosophila grimshawi FBgn0131420 I 0.802
GI14042 Drosophila mojavensis FBgn0136796 I 0.802
GL17563 Drosophila persimilis FBgn0155166 I 0.802
GK13683 Drosophila willistoni FBgn0215691 I 0.802
ENSCSAVG00000007987 Ciona savignyi ENSCSAVG00000007987 I 0.797
ENSTNIG00000002471 Tetraodon nigroviridis ENSTNIG00000002471 I 0.797
PAX6 Monodelphis domestica ENSMODG00000009611 I 0.797
ADAC001560 Anopheles darlingi ADAC001560 I 0.795
toy Drosophila melanogaster FBgn0019650 D 0.792
AMEC021831 Anopheles melas AMEC021831 I 0.791
AFUN011575 Anopheles funestus AFUN011575 I 0.791
MCOS_0000220101 Mesocestoides corti MCOS_0000220101 I 0.791
GM13021 Drosophila sechellia FBgn0167952 I 0.791
GG16402 Drosophila erecta FBgn0108634 I 0.791
HelroG80374 Helobdella robusta HelroG80374 I 0.791
GE14563 Drosophila yakuba FBgn0232162 I 0.791
GF21877 Drosophila ananassae FBgn0098877 I 0.791
ISCW021772 Ixodes scapularis ISCW021772 I 0.790
ACHR009845 Anopheles christyi ACHR009845 I 0.789
ADIR000973 Anopheles dirus ADIR000973 I 0.789
AFUN011570 Anopheles funestus AFUN011570 I 0.789
AATE014626 Anopheles atroparvus AATE014626 I 0.789
AMIN002132 Anopheles minimus AMIN002132 I 0.789
ASTEI06205 Anopheles stephensi ASTEI06205 I 0.789
AQUA008308 Anopheles quadriannulatus AQUA008308 I 0.786
AARA001115 Anopheles arabiensis AARA001115 I 0.786
AGAP000063 Anopheles gambiae AGAP000063 I 0.786
AALB006354 Anopheles albimanus AALB006354 I 0.786
ASTEI06200 Anopheles stephensi ASTEI06200 I 0.786
AMIN002127 Anopheles minimus AMIN002127 I 0.786
ASIS012967 Anopheles sinensis ASIS012967 I 0.786
AEPI005798 Anopheles epiroticus AEPI005798 I 0.785
AFAF017899 Anopheles farauti AFAF017899 I 0.785
AMEM002691 Anopheles merus AMEM002691 I 0.785
AQUA008313 Anopheles quadriannulatus AQUA008313 I 0.785
AGAP000067 Anopheles gambiae AGAP000067 I 0.785
AMEC013051 Anopheles melas AMEC013051 I 0.785
AARA001110 Anopheles arabiensis AARA001110 I 0.785
RSKR_0000862000 Rhabditophanes kr3021 RSKR_0000862000 I 0.780
GD24416 Drosophila simulans FBgn0195753 I 0.778
EFV57892 Trichinella spiralis EFV57892 I 0.775
SVE_0819200 Strongyloides venezuelensis SVE_0819200 I 0.775
SPAL_0001466800 Strongyloides papillosus SPAL_0001466800 I 0.775
AAEL002321 Aedes aegypti AAEL002321 I 0.775
PTRK_0000512100 Parastrongyloides trichosuri PTRK_0000512100 I 0.775
SSTP_0001059400 Strongyloides stercoralis SSTP_0001059400 I 0.775
AFAF009619 Anopheles farauti AFAF009619 I 0.772
ADAC003449 Anopheles darlingi ADAC003449 I 0.772
ACHR008920 Anopheles christyi ACHR008920 I 0.771
L596_g12356 Steinernema carpocapsae L596_g12356 I 0.769
L892_g3713 Steinernema scapterisci L892_g3713 I 0.769
HelroG173449 Helobdella robusta HelroG173449 I 0.767
CBN04513 Caenorhabditis brenneri CBN04513 I 0.764
tetur09g00660 Tetranychus urticae tetur09g00660 I 0.764
CRE07226 Caenorhabditis remanei CRE07226 I 0.764
vab-3 Caenorhabditis elegans WBGene00006870 I 0.764
ASIS012617 Anopheles sinensis ASIS012617 I 0.757
ACUA021227 Anopheles culicifacies ACUA021227 I 0.753
CpipJ_CPIJ006390 Culex pipiens CpipJ_CPIJ006390 I 0.753
CPIJ006390 Culex quinquefasciatus CPIJ006390 I 0.753
AEPI005803 Anopheles epiroticus AEPI005803 I 0.747
ACUA016154 Anopheles culicifacies ACUA016154 I 0.747
AALB006643 Anopheles albimanus AALB006643 I 0.747
D917_00854 Trichinella nativa D917_00854 I 0.747
PAX6 Ornithorhynchus anatinus ENSOANG00000015149 I 0.743
ISCW006352 Ixodes scapularis ISCW006352 I 0.742
TsM_000166900 Taenia solium TsM_000166900 I 0.742
PAX6 Pan troglodytes ENSPTRG00000003474 I 0.737
CpipJ_CPIJ006398 Culex pipiens CpipJ_CPIJ006398 I 0.736
BXY_1643500 Bursaphelenchus xylophilus BXY_1643500 I 0.736
CPIJ006398 Culex quinquefasciatus CPIJ006398 I 0.736
HmN_000466300 Hymenolepis microstoma HmN_000466300 I 0.736
Afo_R014630 Aptenodytes forsteri Afo_R014630 I 0.734
TTAC_0000231001 Hydatigera taeniaeformis TTAC_0000231001 I 0.731
ENSTSYG00000011965 Tarsius syrichta ENSTSYG00000011965 I 0.725
MCINX016249 Melitaea cinxia MCINX016249 I 0.720
ADIR000968 Anopheles dirus ADIR000968 I 0.716
NEMVEDRAFT_v1g168908 Nematostella vectensis NEMVEDRAFT_v1g168908 I 0.709
NEMVEDRAFT_v1g239535 Nematostella vectensis NEMVEDRAFT_v1g239535 I 0.703