pax-3 (Caenorhabditis elegans)
Homeodomain,Paired box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00292 (PAX) 		IPR001356
IPR001523 		WBGene00003939 T237678_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in epidermal cell fate specification; gonad morphogenesis; and hemidesmosome assembly. Located in nucleus. Is expressed in several structures, including AB lineage cell; E lineage cell; P9/10L; hypodermal cell; and tail. Human ortholog(s) of this gene implicated in Waardenburg syndrome type 1; Waardenburg syndrome type 3; Waardenburg's syndrome; alveolar rhabdomyosarcoma; and craniofacial-deafness-hand syndrome. Orthologous to several human genes including PAX3 (paired box 3). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
F27E5.2 Paired box 13 138
F27E5.2 Homeodomain 188 244

Links

Other Homeodomain,Paired box family TFs
Other Caenorhabditis elegans TFs

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8 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action