pou3f3b (Danio rerio)
Homeodomain,POU

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00157 (Pou) 		IPR001356
IPR000327 		ENSDARG00000095896 T238119_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within brain development and regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in nervous system; neural rod; otic vesicle; pronephric duct; and spinal cord neural tube. Human ortholog(s) of this gene implicated in X-linked deafness 2. Orthologous to several human genes including POU3F3 (POU class 3 homeobox 3). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
pou3f3b
M02237_2.00		 Danio rerio
NWWATDHNNN
NNNDHATWWN		 PBM
Weirauch et al.(2014)
pTH9256		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.993 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M02237_2.00 POU 54 125
M02237_2.00 Homeodomain 144 200

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000123893 POU 241 312
ENSDARP00000123893 Homeodomain 331 387
ENSDARP00000124688 POU 241 312
ENSDARP00000124688 Homeodomain 331 387

Links

Other Homeodomain,POU family TFs
Other Danio rerio TFs

Invalid Input OrderBy

2 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action