POU6F2 (Homo sapiens)
Homeodomain,POU

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00157 (Pou) 		IPR001356
IPR000327 		ENSG00000106536 T238191_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
POU6F2
M00362_2.00		 Homo sapiens
VVTAATTANN
NNTAATTABB		 PBM
Barrera et al.(2016)
POU6F2_E639K		 (Direct) (Direct)
POU6F2
M00363_2.00		 Homo sapiens
NTAABNNN
NNNVTTAN		 PBM
Barrera et al.(2016)
POU6F2_REF		 (Direct) (Direct)
POU6F2
M03303_2.00		 Homo sapiens
DVCTMATTAH
DTAATKAGBH		 SELEX
Jolma et al.(2013)
POU6F2_1		 (Direct) (Direct)
POU6F2
M03304_2.00		 Homo sapiens
HTAATKAGCTMATTAD
HTAATKAGCTMATTAD		 SELEX
Jolma et al.(2013)
POU6F2_2		 (Direct) (Direct)
POU6F2
M03305_2.00		 Homo sapiens
NNTAATKAGS
SCTMATTANN		 SELEX
Jolma et al.(2013)
POU6F2_3		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.993 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00362_2.00 POU 19 69
M00362_2.00 POU 82 126
M00362_2.00 Homeodomain 148 204
M00363_2.00 POU 19 69
M00363_2.00 POU 82 126
M00363_2.00 Homeodomain 148 204

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000384004 POU 479 529
ENSP00000384004 POU 542 586
ENSP00000384004 Homeodomain 608 664
ENSP00000430514 POU 479 550
ENSP00000430514 Homeodomain 572 628
ENSP00000452633 POU 424 474
ENSP00000452633 POU 487 531
ENSP00000452633 Homeodomain 553 609

Links

Other Homeodomain,POU family TFs
Other Homo sapiens TFs

46 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
POU6F2 Pteropus vampyrus ENSPVAG00000012960 I 1.000
Pou6f2 Rattus norvegicus ENSRNOG00000013237 I 1.000
ENSSHAG00000010659 Sarcophilus harrisii ENSSHAG00000010659 N 1.000
POU6F2 Pan troglodytes ENSPTRG00000019105 I 1.000
ENSPSIG00000017568 Pelodiscus sinensis ENSPSIG00000017568 I 1.000
ENSACAG00000017612 Anolis carolinensis ENSACAG00000017612 N 1.000
ENSOANG00000003587 Ornithorhynchus anatinus ENSOANG00000003587 N 1.000
ENSPANG00000007998 Papio anubis ENSPANG00000007998 I 1.000
ENSSTOG00000023336 Ictidomys tridecemlineatus ENSSTOG00000023336 I 1.000
POU6F2 Taeniopygia guttata ENSTGUG00000001859 I 1.000
Gfo_R007861 Geospiza fortis Gfo_R007861 I 1.000
Pvit_04153 Pogona vitticeps Pvit_04153 I 1.000
pou6f2 Xenopus tropicalis XB-GENE-853682 I 1.000
ENSP00000395926 Macaca fascicularis ENSP00000395926 I 1.000
ENSP00000395926-D1 Bos grunniens ENSP00000395926-D1 I 1.000
Aan_R014018 Calypte anna Aan_R014018 I 1.000
Afo_R007505 Aptenodytes forsteri Afo_R007505 I 1.000
Cmyd_10020861 Chelonia mydas Cmyd_10020861 N 1.000
Pou6f2 Mus musculus ENSMUSG00000009734 I 1.000
ENSNLEG00000003036 Nomascus leucogenys ENSNLEG00000003036 I 1.000
ENSFALG00000005224 Ficedula albicollis ENSFALG00000005224 I 1.000
POU6F2 Choloepus hoffmanni ENSCHOG00000003691 I 1.000
POU6F2 Echinops telfairi ENSETEG00000016373 I 1.000
POU6F2 Erinaceus europaeus ENSEEUG00000006653 I 1.000
POU6F2 Equus caballus ENSECAG00000013209 I 1.000
ENSCPOG00000012221 Cavia porcellus ENSCPOG00000012221 I 1.000
POU6F2 Gorilla gorilla ENSGGOG00000006718 I 1.000
POU6F2 Loxodonta africana ENSLAFG00000008294 I 1.000
ENSAPLG00000005140 Anas platyrhynchos ENSAPLG00000005140 I 1.000
POU6F2 Macaca mulatta ENSMMUG00000017106 I 1.000
POU6F2 Microcebus murinus ENSMICG00000007361 I 1.000
POU6F2 Canis familiaris ENSCAFG00000003571 I 1.000
ENSCSAG00000015201 Chlorocebus sabaeus ENSCSAG00000015201 I 1.000
ENSLOCG00000011317 Lepisosteus oculatus ENSLOCG00000011317 I 1.000
Ogr18087 Ophisaurus gracilis Ogr18087 I 0.994
Tal_R002298 Tyto alba Tal_R002298 I 0.994
Myotis_brandtii_POU6F2_10011220 Myotis brandtii Myotis_brandtii_POU6F2_10011220 I 0.994
ENSFCAG00000008102 Felis catus ENSFCAG00000008102 I 0.994
ENSOARG00000017698 Ovis aries ENSOARG00000017698 I 0.994
ENSMLUG00000002698 Myotis lucifugus ENSMLUG00000002698 I 0.994
ENSOGAG00000033061 Otolemur garnettii ENSOGAG00000033061 I 0.994
ENSMGAG00000012235 Meleagris gallopavo ENSMGAG00000012235 I 0.994
ENSMPUG00000018132 Mustela putorius furo ENSMPUG00000018132 I 0.994
ENSLACG00000002338 Latimeria chalumnae ENSLACG00000002338 I 0.994
Brh_R001259 Buceros rhinoceros Brh_R001259 I 0.994