POU5F1 (Homo sapiens)
Homeodomain,POU

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00157 (Pou) 		IPR001356
IPR000327 		ENSG00000204531 T238200_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
POU5F1
M05501_2.00		 Homo sapiens
NNWTATGYWAATKWVB
VBWMATTWRCATAWNN		 SELEX
Yin et al.(2017)
POU5F1_FL_HT-SELEX		 (Direct) (Direct)
POU5F1
M05502_2.00		 Homo sapiens
DTATGCGCATAH
DTATGCGCATAH		 SELEX
Yin et al.(2017)
POU5F1_FL_Methyl-HT-SELEX_1		 (Direct) (Direct)
POU5F1
M05503_2.00		 Homo sapiens
NDWTATGYWAATKARB
VYTMATTWRCATAWHN		 SELEX
Yin et al.(2017)
POU5F1_FL_Methyl-HT-SELEX_2		 (Direct) (Direct)
POU5F1
M05504_2.00		 Homo sapiens
NYDCGCATAATTARB
VYTAATTATGCGHRN		 SELEX
Yin et al.(2017)
POU5F1_FL_Methyl-HT-SELEX_3		 (Direct) (Direct)
POU5F1
M05875_2.00		 Homo sapiens
NDTATGYWAATN
NATTWRCATAHN		 SMiLE-seq
Isakova et al.(2017)
OCT4		 (Direct) (Direct)
POU5F1
M07976_2.00		 Homo sapiens
NYYWTTSWYATGCARAH
DTYTGCATRWSAAWRRN		 ChIP-seq
Gerstein et al.(2012)
H1-hESC_POU5F1_HudsonAlpha		 (Direct) (Direct)
POU5F1
M08141_2.00		 Homo sapiens
DNATGCAAANN
NNTTTGCATNH		 ChIP-seq
Mathelier et al.(2014)
MA1115.1		 (Direct) (Direct)
POU5F1
M09222_2.00		 Homo sapiens
BYWTTSWHATGCARAH
DTYTGCATDWSAAWRV		 Misc
Kulakovskiy et al.(2013)
PO5F1_HUMAN.H11MO.0.A		 (Direct) (Direct)
POU5F1
M10851_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$OCT3_Q6		 (Direct) (Direct)
POU5F1
M10852_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$POU5F1_01		 (Direct) (Direct)
POU5F1
M10853_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$POU5F1_04		 (Direct) (Direct)
POU5F1
M10854_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$POU5F1_05		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.993 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000259915 POU 141 212
ENSP00000259915 Homeodomain 231 287
ENSP00000389359 POU 1 16
ENSP00000389359 Homeodomain 35 91
ENSP00000425083 POU 1 16
ENSP00000425083 Homeodomain 35 91
ENSP00000425479 POU 1 16
ENSP00000425479 Homeodomain 35 91
ENSP00000475512 POU 1 16
ENSP00000475512 Homeodomain 35 91
ENSP00000475880 POU 1 42
ENSP00000475880 Homeodomain 61 117
ENSP00000481679 POU 141 173
ENSP00000484778 POU 1 42
ENSP00000484778 Homeodomain 61 117

Links

Other Homeodomain,POU family TFs
Other Homo sapiens TFs

10 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
POU5F1 Pan troglodytes ENSPTRG00000017953 I 1.000
ENSPPYG00000017210 Pongo abelii ENSPPYG00000017210 I 1.000
ENSNLEG00000005802 Nomascus leucogenys ENSNLEG00000005802 I 1.000
ENSGGOG00000027662 Gorilla gorilla ENSGGOG00000027662 I 1.000
POU5F1 Callithrix jacchus ENSCJAG00000019789 I 0.917
ENSPANG00000015262 Papio anubis ENSPANG00000015262 N 0.848
POU5F1 Macaca mulatta ENSMMUG00000015688 N 0.824
Myotis_brandtii_POU5F1_10022640 Myotis brandtii Myotis_brandtii_POU5F1_10022640 N 0.818
ENSCPOG00000009976 Cavia porcellus ENSCPOG00000009976 N 0.727