CIS-BP Database: Catalog of Inferred Sequence Binding Preferences - Update
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Pou6f2
(
Mus musculus
)
Homeodomain,POU
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00046 (Homeobox)
PF00157 (Pou)
IPR001356
IPR000327
ENSMUSG00000009734
T238375_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in central nervous system; eye; and reproductive system. Human ortholog(s) of this gene implicated in nephroblastoma. Orthologous to human POU6F2 (POU class 6 homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
POU6F2
M00363_2.00
Homo sapiens
NTAABNNN
NNNVTTAN
PBM
Barrera et al.(2016)
POU6F2_REF
1.000
1.000
POU6F2
M03303_2.00
Homo sapiens
DVCTMATTAH
DTAATKAGBH
SELEX
Jolma et al.(2013)
POU6F2_1
1.000
1.000
POU6F2
M03304_2.00
Homo sapiens
HTAATKAGCTMATTAD
HTAATKAGCTMATTAD
SELEX
Jolma et al.(2013)
POU6F2_2
1.000
1.000
POU6F2
M03305_2.00
Homo sapiens
NNTAATKAGS
SCTMATTANN
SELEX
Jolma et al.(2013)
POU6F2_3
1.000
1.000
For this family, TFs with SR scores >
0.993
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSMUSP00000114173
POU
425
475
VNLEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTILR
ENSMUSP00000114173
POU
488
532
TIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAE
ENSMUSP00000114173
Homeodomain
554
610
RKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQALKN
ENSMUSP00000139282
POU
425
496
VNLEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRFEKLDITPKSAQKIKPVLERWMAEAE
ENSMUSP00000139282
Homeodomain
518
574
RKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQALKN
Links
Other
Homeodomain,POU
family TFs
Other
Mus musculus
TFs
45 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy