Pou5f1 (Mus musculus)
Homeodomain,POU

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00157 (Pou)
IPR001356
IPR000327
ENSMUSG00000024406 T238377_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
The protein encoded by this gene belongs to the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein plays a key role in embryonic development and stem cell pluripotency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Pou5f1
M08031_2.00
Mus musculus
YYWTTNWHWTKBWAA

TTWVMAWDWNAAWRR
ChIP-seq
Chen et al.(2011)
GSE11329_bioOct4
(Direct) (Direct)
Pou5f1
M08032_2.00
Mus musculus
BYWTTSWHATGCADA

THTGCATDWSAAWRV
ChIP-seq
Chen et al.(2011)
SRP000217_Oct4
(Direct) (Direct)
Pou5f1
M08033_2.00
Mus musculus
YWTTSWNATGCWAAW

WTTWGCATNWSAAWR
ChIP-seq
Chen et al.(2011)
SRP000712_Oct4
(Direct) (Direct)
Pou5f1
M09225_2.00
Mus musculus
BYWTTSWNATGCWAAW

WTTWGCATNWSAAWRV
Misc
Kulakovskiy et al.(2013)
PO5F1_MOUSE.H11MO.0.A
(Direct) (Direct)
Pou5f1
M10855_2.00
Mus musculus Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$OCT4_01
(Direct) (Direct)
Pou5f1
M10856_2.00
Mus musculus Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$OCT4_02
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.993 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000025271 POU 134 205
ENSMUSP00000025271 Homeodomain 224 280
ENSMUSP00000133633 POU 3 74
ENSMUSP00000133633 Homeodomain 93 132
ENSMUSP00000134060 POU 3 74
ENSMUSP00000134060 Homeodomain 93 132
ENSMUSP00000134493 POU 28 99
ENSMUSP00000134493 Homeodomain 118 157
ENSMUSP00000134654 POU 3 74
ENSMUSP00000134654 Homeodomain 93 132
ENSMUSP00000134729 POU 3 74
ENSMUSP00000134729 Homeodomain 93 132

Links

Other Homeodomain,POU family TFs
Other Mus musculus TFs

1 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSAMEG00000000496 Ailuropoda melanoleuca ENSAMEG00000000496 N 0.000
THAP2 Bos taurus ENSBTAG00000012271 N 0.000
ENSBTAP00000016276-D2 Bos grunniens ENSBTAP00000016276-D2 N 0.000
THAP2 Canis familiaris ENSCAFG00000000456 N 0.000
THAP2 Callithrix jacchus ENSCJAG00000001382 N 0.000
THAP2 Cavia porcellus ENSCPOG00000009524 N 0.000
ENSDNOG00000049696 Dasypus novemcinctus ENSDNOG00000049696 N 0.000
Thap2 Dipodomys ordii ENSDORG00000006270 N 0.000
THAP2 Homo sapiens ENSG00000173451 N 0.000
THAP2 Gorilla gorilla ENSGGOG00000015483 N 0.000
ENSLACG00000005196 Latimeria chalumnae ENSLACG00000005196 N 0.000
ENSMEUG00000015495 Macropus eugenii ENSMEUG00000015495 N 0.000
THAP2 Myotis lucifugus ENSMLUG00000004164 N 0.000
ENSMMUG00000020946 Macaca mulatta ENSMMUG00000020946 N 0.000
ENSMMUP00000027563 Macaca fascicularis ENSMMUP00000027563 N 0.000
ENSMPUG00000017487 Mustela putorius furo ENSMPUG00000017487 N 0.000
ENSMPUG00000019081 Mustela putorius furo ENSMPUG00000019081 N 0.000
Thap2 Mus musculus ENSMUSG00000020137 N 0.000
ENSNLEG00000004398 Nomascus leucogenys ENSNLEG00000004398 N 0.000
ENSOARG00000014616 Ovis aries ENSOARG00000014616 N 0.000
THAP2 Oryctolagus cuniculus ENSOCUG00000013308 N 0.000
THAP2 Otolemur garnettii ENSOGAG00000027278 N 0.000
THAP2 Ochotona princeps ENSOPRG00000013944 N 0.000
THAP2 Procavia capensis ENSPCAG00000003970 N 0.000
ENSPPYG00000004774 Pongo abelii ENSPPYG00000004774 N 0.000
ENSPSIG00000012990 Pelodiscus sinensis ENSPSIG00000012990 N 0.000
THAP2 Pan troglodytes ENSPTRG00000005225 N 0.000
THAP2 Pteropus vampyrus ENSPVAG00000012359 N 0.000
Thap2 Rattus norvegicus ENSRNOG00000003993 N 0.000
THAP2 Sorex araneus ENSSARG00000010362 N 0.000
THAP2 Sus scrofa ENSSSCG00000021270 N 0.000
ENSSTOG00000002694 Ictidomys tridecemlineatus ENSSTOG00000002694 N 0.000
THAP2 Tupaia belangeri ENSTBEG00000016924 N 0.000
ENSTSYG00000005486 Tarsius syrichta ENSTSYG00000005486 N 0.000
THAP2 Tursiops truncatus ENSTTRG00000007330 N 0.000
THAP2 Vicugna pacos ENSVPAG00000010909 N 0.000