CIS-BP Database: Catalog of Inferred Sequence Binding Preferences - Update
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Pou2f3
(
Mus musculus
)
Homeodomain,POU
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00046 (Homeobox)
PF00157 (Pou)
IPR001356
IPR000327
ENSMUSG00000032015
T238381_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Enables identical protein binding activity and sequence-specific DNA binding activity. Acts upstream of or within keratinocyte differentiation; positive regulation of transcription by RNA polymerase II; and wound healing. Part of transcription regulator complex. Is expressed in several structures, including early conceptus; genitourinary system; gut; skin; and thymus. Orthologous to human POU2F3 (POU class 2 homeobox 3). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Pou2f3
M00549_2.00
Mus musculus
NNWWATKHN
NDMATWWNN
PBM
Berger et al.(2008)
Pou2f3_3986
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
For this family, TFs with SR scores >
0.993
will likely have a similar motif
Experimental Constructs
Motif ID
Domain
From
To
Sequence
M00549_2.00
POU
19
90
TDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAE
M00549_2.00
Homeodomain
115
171
RKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKR
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSMUSP00000034513
POU
167
238
TDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAE
ENSMUSP00000034513
Homeodomain
263
319
RKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKR
ENSMUSP00000135115
POU
179
250
TDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAE
ENSMUSP00000135115
Homeodomain
275
331
RKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKR
Links
Other
Homeodomain,POU
family TFs
Other
Mus musculus
TFs
4 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy