CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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Pou4f1
(
Mus musculus
)
Homeodomain,POU
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00046 (Homeobox)
PF00157 (Pou)
IPR001356
IPR000327
ENSMUSG00000048349
T238382_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Enables several functions, including DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and GTPase binding activity. Involved in several processes, including cellular response to estradiol stimulus; nervous system development; and regulation of gene expression. Acts upstream of or within several processes, including nervous system development; proprioception involved in equilibrioception; and suckling behavior. Located in several cellular components, including chromatin; neuron projection; and nucleus. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including branchial arch mesenchyme; central nervous system; future brain; ganglia; and retina. Orthologous to human POU4F1 (POU class 4 homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
POU4F1
M03312_2.00
Homo sapiens
NTRMATWATTNATD
HATNAATWATKYAN
SELEX
Jolma et al.(2013)
POU4F1_1
1.000
1.000
POU4F1
M05470_2.00
Homo sapiens
NTDMATWATKYAN
NTRMATWATKHAN
SELEX
Yin et al.(2017)
POU4F1_eDBD_HT-SELEX_1
1.000
1.000
POU4F1
M05471_2.00
Homo sapiens
VTGCATWATKNAN
NTNMATWATGCAB
SELEX
Yin et al.(2017)
POU4F1_eDBD_HT-SELEX_2
1.000
1.000
POU4F1
M10841_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$POU4F1_Q3
1.000
1.000
POU4F1
M10842_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$POU4F1_Q6
1.000
1.000
POU4F1
M05472_2.00
Homo sapiens
DTGMATWATTNAT
ATNAATWATKCAH
SELEX
Yin et al.(2017)
POU4F1_eDBD_Methyl-HT-SELEX
1.000
1.000
For this family, TFs with SR scores >
0.993
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSMUSP00000060798
POU
265
339
TDPRELEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAE
ENSMUSP00000060798
Homeodomain
358
414
KRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR
Links
Other
Homeodomain,POU
family TFs
Other
Mus musculus
TFs
21 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy