Pou4f1 (Mus musculus)
Homeodomain,POU

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00157 (Pou) 		IPR001356
IPR000327 		ENSMUSG00000048349 T238382_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables several functions, including DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and GTPase binding activity. Involved in several processes, including cellular response to estradiol stimulus; nervous system development; and regulation of gene expression. Acts upstream of or within several processes, including nervous system development; proprioception involved in equilibrioception; and suckling behavior. Located in several cellular components, including chromatin; neuron projection; and nucleus. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including branchial arch mesenchyme; central nervous system; future brain; ganglia; and retina. Orthologous to human POU4F1 (POU class 4 homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
POU4F1
M03312_2.00 		Homo sapiens
NTRMATWATTNATD
HATNAATWATKYAN		 SELEX
Jolma et al.(2013)
POU4F1_1 		1.000 1.000
POU4F1
M05470_2.00 		Homo sapiens
NTDMATWATKYAN
NTRMATWATKHAN		 SELEX
Yin et al.(2017)
POU4F1_eDBD_HT-SELEX_1 		1.000 1.000
POU4F1
M05471_2.00 		Homo sapiens
VTGCATWATKNAN
NTNMATWATGCAB		 SELEX
Yin et al.(2017)
POU4F1_eDBD_HT-SELEX_2 		1.000 1.000
POU4F1
M10841_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$POU4F1_Q3 		1.000 1.000
POU4F1
M10842_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$POU4F1_Q6 		1.000 1.000
POU4F1
M05472_2.00 		Homo sapiens
DTGMATWATTNAT
ATNAATWATKCAH		 SELEX
Yin et al.(2017)
POU4F1_eDBD_Methyl-HT-SELEX 		1.000 1.000
For this family, TFs with SR scores > 0.993 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000060798 POU 265 339
ENSMUSP00000060798 Homeodomain 358 414

Links

Other Homeodomain,POU family TFs
Other Mus musculus TFs

Invalid Input OrderBy

21 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action