CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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Pou3f3
(
Rattus norvegicus
)
Homeodomain,POU
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00046 (Homeobox)
PF00157 (Pou)
IPR001356
IPR000327
ENSRNOG00000038909
T238585_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Enables DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in positive regulation of gene expression and positive regulation of transcription by RNA polymerase II. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleus. Orthologous to human POU3F3 (POU class 3 homeobox 3). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
D2GWY1_AILME
M02236_2.00
Ailuropoda melanoleuca
NNNATTANN
NNTAATNNN
PBM
Weirauch et al.(2014)
pTH9216
1.000
1.000
POU3F3
M03319_2.00
Homo sapiens
WWTATGYWAATDW
WHATTWRCATAWW
SELEX
Jolma et al.(2013)
POU3F3_1
1.000
1.000
POU3F3
M03320_2.00
Homo sapiens
WTGMATAAWTWW
WWAWTTATKCAW
SELEX
Jolma et al.(2013)
POU3F3_2
1.000
1.000
POU3F3
M03321_2.00
Homo sapiens
WWDMWTAWKHAW
WTDMWTAWKHWW
SELEX
Jolma et al.(2013)
POU3F3_3
1.000
1.000
POU3F3
M10850_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$BRN1_Q6
1.000
1.000
For this family, TFs with SR scores >
0.993
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSRNOP00000040234
POU
282
353
PTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD
ENSRNOP00000040234
Homeodomain
372
428
RKKRTSIEVSVKGALESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKR
ENSRNOP00000073663
POU
304
375
PTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEAD
ENSRNOP00000073663
Homeodomain
394
450
RKKRTSIEVSVKGALESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKR
Links
Other
Homeodomain,POU
family TFs
Other
Rattus norvegicus
TFs
22 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy