irf1a (Danio rerio)
IRF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00605 (IRF) IPR001346 ENSDARG00000043492 T244015_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in immune system process and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be active in nucleus. Is expressed in several structures, including blood; digestive system; eye; immune system; and integument. Human ortholog(s) of this gene implicated in asthma; gastric adenocarcinoma; lung non-small cell carcinoma; and smallpox. Orthologous to human IRF1 (interferon regulatory factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Irf2
M00805_2.00 		Mus musculus
NDWNHGAAAV
BTTTCDNWHN		 PBM
Weirauch et al.(2013)
pTH2835 		0.724 0.724
Irf2
M09245_2.00 		Mus musculus
NRAANNGAAASYGAAASYRV
BYRSTTTCRSTTTCNNTTYN		 Misc
Kulakovskiy et al.(2013)
IRF2_MOUSE.H11MO.0.B 		0.724 0.724
IRF2
M05545_2.00 		Homo sapiens
NGAAAVYGAAAS
STTTCRBTTTCN		 SELEX
Yin et al.(2017)
IRF2_FL_HT-SELEX 		0.705 0.705
IRF2
M02691_2.00 		Homo sapiens
SGAAAGYGAAASYNWWHH
DDWWNRSTTTCRCTTTCS		 SELEX
Mathelier et al.(2014)
MA0051.1 		0.705 0.705
IRF2
M09237_2.00 		Homo sapiens
NRAANNGAAASYGAAASYRV
BYRSTTTCRSTTTCNNTTYN		 Misc
Kulakovskiy et al.(2013)
IRF2_HUMAN.H11MO.0.A 		0.705 0.705
IRF2
M09596_2.00 		Homo sapiens
NRAAVNRRAASB
VSTTYYNBTTYN		 Misc
Heinz et al.(2010)
Erythroblas-IRF2_GSE36985 		0.705 0.705
IRF2
M10892_2.00 		Homo sapiens
GAAAAGYGAAASY
RSTTTCRCTTTTC		 Transfac
Matys et al.(2006)
V$IRF2_01 		0.705 0.705
IRF2
M10893_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF2_Q6 		0.705 0.705
IRF2
M05546_2.00 		Homo sapiens
NGAAASYGAAAS
STTTCRSTTTCN		 SELEX
Yin et al.(2017)
IRF2_FL_Methyl-HT-SELEX 		0.705 0.705
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000070128 IRF 7 112

Links

Other IRF family TFs
Other Danio rerio TFs

Invalid Input OrderBy

52 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action