Irf4 (Mus musculus)
IRF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00605 (IRF) IPR001346 ENSMUSG00000021356 T244219_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Irf4
M00175_2.00
Mus musculus
NNNYGAWASN

NSTWTCRNNN
PBM
Badis et al.(2009)
Irf4_3476
(Direct) (Direct)
Irf4
M09243_2.00
Mus musculus
NDAWVVRGAASTGARAVH

DBTYTCASTTCYBBWTHN
Misc
Kulakovskiy et al.(2013)
IRF4_MOUSE.H11MO.0.A
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
IRF4
M03334_2.00
Homo sapiens
HCGAAACCGAAACYW

WRGTTTCGGTTTCGD
SELEX
Jolma et al.(2013)
IRF4_1
0.990 0.990
IRF4
M05539_2.00
Homo sapiens
NYGAAACYGAAACYN

NRGTTTCRGTTTCRN
SELEX
Yin et al.(2017)
IRF4_FL_HT-SELEX
0.990 0.990
IRF4
M07978_2.00
Homo sapiens
DNDVNNGWWVTGAVWVWN

NWBWBTCABWWCNNBHNH
ChIP-seq
Gerstein et al.(2012)
GM12878_IRF4_HudsonAlpha
0.990 0.990
IRF4
M09235_2.00
Homo sapiens
NDWDRRGGAASTGARAVH

DBTYTCASTTCCYYHWHN
Misc
Kulakovskiy et al.(2013)
IRF4_HUMAN.H11MO.0.A
0.990 0.990
IRF4
M09595_2.00
Homo sapiens
HNYGAAASYD

HRSTTTCRND
Misc
Heinz et al.(2010)
GM12878-IRF4_GSE32465
0.990 0.990
IRF4
M10885_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$IRF4_07
0.990 0.990
IRF4
M10886_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$IRF4_08
0.990 0.990
IRF4
M10887_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$IRF4_Q5_01
0.990 0.990
IRF4
M10888_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$IRF4_Q5
0.990 0.990
IRF4
M10889_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$IRF4_Q6
0.990 0.990
IRF4
M05540_2.00
Homo sapiens
NYGAAASYGAWASHN

NDSTWTCRSTTTCRN
SELEX
Yin et al.(2017)
IRF4_FL_Methyl-HT-SELEX
0.990 0.990
IRF8
M03335_2.00
Homo sapiens
HCGAAACYGAAACY

RGTTTCRGTTTCGD
SELEX
Jolma et al.(2013)
IRF8_1
0.810 0.810
IRF8
M03336_2.00
Homo sapiens
HCGAAACCGAAACT

AGTTTCGGTTTCGD
SELEX
Jolma et al.(2013)
IRF8_2
0.810 0.810
IRF8
M05541_2.00
Homo sapiens
NYGAAASYGAAASHN

NDSTTTCRSTTTCRN
SELEX
Yin et al.(2017)
IRF8_eDBD_HT-SELEX
0.810 0.810
IRF8
M05543_2.00
Homo sapiens
NCGAAACYGAAACYN

NRGTTTCRGTTTCGN
SELEX
Yin et al.(2017)
IRF8_FL_HT-SELEX
0.810 0.810
IRF8
M09236_2.00
Homo sapiens
NDDDRRGGAASTGAAASYNN

NNRSTTTCASTTCCYYHHHN
Misc
Kulakovskiy et al.(2013)
IRF8_HUMAN.H11MO.0.B
0.810 0.810
IRF8
M10890_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$ICSBP_Q6
0.810 0.810
IRF8
M10891_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$IRF8_Q6
0.810 0.810
IRF8
M05542_2.00
Homo sapiens
NYGAAASYGAAASYN

NRSTTTCRSTTTCRN
SELEX
Yin et al.(2017)
IRF8_eDBD_Methyl-HT-SELEX
0.810 0.810
IRF8
M05544_2.00
Homo sapiens
NYGAAASYGAAACYD

HRGTTTCRSTTTCRN
SELEX
Yin et al.(2017)
IRF8_FL_Methyl-HT-SELEX
0.810 0.810
Irf8
M09246_2.00
Mus musculus
NDDDRRGGAASTGAAASYNN

NNRSTTTCASTTCCYYHHHN
Misc
Kulakovskiy et al.(2013)
IRF8_MOUSE.H11MO.0.A
0.790 0.790
For this family, TFs with SR scores > 0.700 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00175_2.00 IRF 22 127

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000021784 IRF 23 128
ENSMUSP00000105936 IRF 23 128

Links

Other IRF family TFs
Other Mus musculus TFs

170 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSMICG00000011721 Microcebus murinus ENSMICG00000011721 I 1.000
Irf4 Rattus norvegicus ENSRNOG00000061070 I 1.000
ENSTSYG00000006495 Tarsius syrichta ENSTSYG00000006495 I 1.000
IRF4 Choloepus hoffmanni ENSCHOG00000012417 I 1.000
ENSP00000370343 Macaca fascicularis ENSP00000370343 I 1.000
IRF4 Myotis lucifugus ENSMLUG00000010058 I 0.990
ENSMPUG00000007848 Mustela putorius furo ENSMPUG00000007848 I 0.990
IRF4 Loxodonta africana ENSLAFG00000017235 I 0.990
IRF4 Macaca mulatta ENSMMUG00000018513 I 0.990
IRF4 Felis catus ENSFCAG00000022941 I 0.990
IRF4 Equus caballus ENSECAG00000016808 I 0.990
IRF4 Erinaceus europaeus ENSEEUG00000007703 I 0.990
IRF4 Echinops telfairi ENSETEG00000018472 I 0.990
IRF4 Homo sapiens ENSG00000137265 D 0.990
IRF4 Gorilla gorilla ENSGGOG00000012342 I 0.990
ENSOARG00000003822 Ovis aries ENSOARG00000003822 I 0.990
IRF4 Pteropus vampyrus ENSPVAG00000005078 I 0.990
ENSSTOG00000011470 Ictidomys tridecemlineatus ENSSTOG00000011470 I 0.990
IRF4 Tupaia belangeri ENSTBEG00000012240 I 0.990
ENSP00000370343-D1 Bos grunniens ENSP00000370343-D1 I 0.990
IRF4 Pan troglodytes ENSPTRG00000017656 I 0.990
ENSPSIG00000011619 Pelodiscus sinensis ENSPSIG00000011619 I 0.990
Irf4 Dipodomys ordii ENSDORG00000014895 I 0.990
IRF4 Otolemur garnettii ENSOGAG00000014574 I 0.990
IRF4 Ochotona princeps ENSOPRG00000012683 I 0.990
ENSPPYG00000016161 Pongo abelii ENSPPYG00000016161 I 0.990
ENSNLEG00000010631 Nomascus leucogenys ENSNLEG00000010631 I 0.990
IRF4 Oryctolagus cuniculus ENSOCUG00000009374 I 0.990
IRF4 Bos taurus ENSBTAG00000002929 I 0.990
ENSCSAG00000007164 Chlorocebus sabaeus ENSCSAG00000007164 I 0.990
IRF4 Callithrix jacchus ENSCJAG00000019524 I 0.990
IRF4 Cavia porcellus ENSCPOG00000003562 I 0.990
ENSAMEG00000005976 Ailuropoda melanoleuca ENSAMEG00000005976 I 0.990
Tal_R010571 Tyto alba Tal_R010571 I 0.983
ENSPANG00000023389 Papio anubis ENSPANG00000023389 I 0.982
ENSGALG00000012830 Gallus gallus ENSGALG00000012830 I 0.981
ENSMEUG00000002440 Macropus eugenii ENSMEUG00000002440 I 0.981
IRF4 Monodelphis domestica ENSMODG00000008383 I 0.981
ENSAPLG00000014646 Anas platyrhynchos ENSAPLG00000014646 I 0.981
IRF4 Tursiops truncatus ENSTTRG00000001849 I 0.981
Alligator_sinensis_CCG015622.1 Alligator sinensis Alligator_sinensis_CCG015622.1 I 0.981
Cmyd_10011521 Chelonia mydas Cmyd_10011521 I 0.981
Gfo_R003357 Geospiza fortis Gfo_R003357 I 0.981
Afo_R014746 Aptenodytes forsteri Afo_R014746 I 0.981
ENSFALG00000013071 Ficedula albicollis ENSFALG00000013071 I 0.981
IRF4 Taeniopygia guttata ENSTGUG00000002144 I 0.981
Aan_R012662 Calypte anna Aan_R012662 I 0.981
ENSSHAG00000015592 Sarcophilus harrisii ENSSHAG00000015592 I 0.981
IRF4 Procavia capensis ENSPCAG00000010586 I 0.980
Myotis_brandtii_Irf4_10020370 Myotis brandtii Myotis_brandtii_Irf4_10020370 I 0.971
Brh_R000433 Buceros rhinoceros Brh_R000433 I 0.971
Pvit_05673 Pogona vitticeps Pvit_05673 I 0.971
Ogr05775 Ophisaurus gracilis Ogr05775 I 0.962
IRF4 Anolis carolinensis ENSACAG00000017711 I 0.962
ENSLOCG00000013008 Lepisosteus oculatus ENSLOCG00000013008 I 0.952
irf4 Xenopus tropicalis XB-GENE-988321 I 0.952
irf4b Takifugu rubripes ENSTRUG00000002946 I 0.943
IRF4 Ornithorhynchus anatinus ENSOANG00000006326 I 0.934
ENSAMXG00000006093 Astyanax mexicanus ENSAMXG00000006093 I 0.933
irf4b Tetraodon nigroviridis ENSTNIG00000008222 I 0.933
irf4b Oryzias latipes ENSORLG00000012712 I 0.933
ENSPFOG00000000657 Poecilia formosa ENSPFOG00000000657 I 0.924
ENSONIG00000006398 Oreochromis niloticus ENSONIG00000006398 I 0.924
irf4b Gasterosteus aculeatus ENSGACG00000004966 I 0.924
ENSXMAG00000006246 Xiphophorus maculatus ENSXMAG00000006246 I 0.924
irf4b Danio rerio ENSDARG00000055374 I 0.924
ENSGMOG00000016994 Gadus morhua ENSGMOG00000016994 I 0.914
irf4a Danio rerio ENSDARG00000006560 I 0.905
irf4a Oryzias latipes ENSORLG00000017242 I 0.905
ENSAMXG00000016370 Astyanax mexicanus ENSAMXG00000016370 I 0.905
ENSPFOG00000015506 Poecilia formosa ENSPFOG00000015506 I 0.886
irf4a Tetraodon nigroviridis ENSTNIG00000005370 I 0.886
ENSXMAG00000017015 Xiphophorus maculatus ENSXMAG00000017015 I 0.886
ENSONIG00000009637 Oreochromis niloticus ENSONIG00000009637 I 0.886
ENSGMOG00000005047 Gadus morhua ENSGMOG00000005047 I 0.876
irf4a Gasterosteus aculeatus ENSGACG00000016461 I 0.876
irf4a Takifugu rubripes ENSTRUG00000011568 I 0.876
ENSAMXG00000012775 Astyanax mexicanus ENSAMXG00000012775 I 0.857
IRF8 Homo sapiens ENSG00000140968 D 0.846
ENSPSIG00000011788 Pelodiscus sinensis ENSPSIG00000011788 I 0.827
Cmyd_10021085 Chelonia mydas Cmyd_10021085 I 0.827
XP_002934991 Xenopus tropicalis XP_002934991 I 0.818
IRF8 Tursiops truncatus ENSTTRG00000016024 I 0.818
Alligator_sinensis_CCG008430.1 Alligator sinensis Alligator_sinensis_CCG008430.1 I 0.817
ENSFALG00000006647 Ficedula albicollis ENSFALG00000006647 I 0.817
IRF8 Monodelphis domestica ENSMODG00000004572 I 0.817
ENSSHAG00000006901 Sarcophilus harrisii ENSSHAG00000006901 I 0.817
ENSMICG00000012090 Microcebus murinus ENSMICG00000012090 I 0.816
ENSMPUG00000008641 Mustela putorius furo ENSMPUG00000008641 I 0.810
ENSAMEG00000018268 Ailuropoda melanoleuca ENSAMEG00000018268 I 0.808
ENSCSAG00000003142 Chlorocebus sabaeus ENSCSAG00000003142 I 0.808
IRF8 Pteropus vampyrus ENSPVAG00000003758 I 0.808
IRF8 Gorilla gorilla ENSGGOG00000028251 I 0.808
IRF8 Myotis lucifugus ENSMLUG00000005109 I 0.808
IRF8 Macaca mulatta ENSMMUG00000008125 I 0.808
IRF8 Felis catus ENSFCAG00000007615 I 0.808
Myotis_brandtii_IRF8_10035313 Myotis brandtii Myotis_brandtii_IRF8_10035313 I 0.808
Pvit_16863 Pogona vitticeps Pvit_16863 I 0.808
Tal_R007108 Tyto alba Tal_R007108 I 0.808
IRF8 Dasypus novemcinctus ENSDNOG00000038898 I 0.808
IRF8 Loxodonta africana ENSLAFG00000010973 I 0.808
ENSP00000268638 Macaca fascicularis ENSP00000268638 I 0.808
IRF8 Pan troglodytes ENSPTRG00000008435 I 0.808
Afo_R011419 Aptenodytes forsteri Afo_R011419 I 0.808
ENSLOCG00000001013 Lepisosteus oculatus ENSLOCG00000001013 I 0.808
Brh_R009589 Buceros rhinoceros Brh_R009589 I 0.808
Aan_R009222 Calypte anna Aan_R009222 I 0.808
ENSCPOG00000027266 Cavia porcellus ENSCPOG00000027266 I 0.808
IRF8 Canis familiaris ENSCAFG00000019919 I 0.808
IRF8 Oryctolagus cuniculus ENSOCUG00000000536 I 0.808
IRF8 Gallus gallus ENSGALG00000005757 I 0.808
IRF8 Procavia capensis ENSPCAG00000004460 I 0.808
ENSPANG00000024770 Papio anubis ENSPANG00000024770 I 0.808
ENSNLEG00000011429 Nomascus leucogenys ENSNLEG00000011429 I 0.808
ENSPPYG00000007620 Pongo abelii ENSPPYG00000007620 I 0.808
IRF8 Callithrix jacchus ENSCJAG00000017331 I 0.798
Gfo_R000501 Geospiza fortis Gfo_R000501 I 0.798
IRF8 Bos taurus ENSBTAG00000017824 I 0.798
ENSLACG00000005859 Latimeria chalumnae ENSLACG00000005859 I 0.798
ENSOARG00000011513 Ovis aries ENSOARG00000011513 I 0.798
Irf8 Rattus norvegicus ENSRNOG00000017869 I 0.798
IRF8 Anolis carolinensis ENSACAG00000005409 I 0.798
IRF8 Ochotona princeps ENSOPRG00000002139 I 0.798
ENSSTOG00000028363 Ictidomys tridecemlineatus ENSSTOG00000028363 I 0.798
ENSP00000268638-D1 Bos grunniens ENSP00000268638-D1 I 0.798
Irf8 Mus musculus ENSMUSG00000041515 D 0.790
ENSLACG00000007228 Latimeria chalumnae ENSLACG00000007228 I 0.790
IRF8 Otolemur garnettii ENSOGAG00000009262 I 0.790
IRF8 Ornithorhynchus anatinus ENSOANG00000003741 I 0.790
irf8.L Xenopus laevis XB-GENE-985949 I 0.790
ENSLOCG00000003532 Lepisosteus oculatus ENSLOCG00000003532 I 0.781
IRF8 Tupaia belangeri ENSTBEG00000013828 I 0.779
Ogr08841 Ophisaurus gracilis Ogr08841 I 0.775
irf10 Danio rerio ENSDARG00000027658 I 0.771
IRF8 Erinaceus europaeus ENSEEUG00000002644 I 0.769
IRF8 Equus caballus ENSECAG00000015449 I 0.763
irf8 Oryzias latipes ENSORLG00000018216 I 0.762
ENSXMAG00000003082 Xiphophorus maculatus ENSXMAG00000003082 I 0.760
ENSAMXG00000003452 Astyanax mexicanus ENSAMXG00000003452 I 0.760
Gfo_R005312 Geospiza fortis Gfo_R005312 I 0.754
Afo_R010468 Aptenodytes forsteri Afo_R010468 I 0.754
irf8 Takifugu rubripes ENSTRUG00000018213 I 0.752
ENSAMXG00000002697 Astyanax mexicanus ENSAMXG00000002697 I 0.752
ENSPFOG00000017639 Poecilia formosa ENSPFOG00000017639 I 0.750
irf8 Danio rerio ENSDARG00000056407 I 0.750
ENSTGUG00000006609 Taeniopygia guttata ENSTGUG00000006609 I 0.743
ENSFALG00000005506 Ficedula albicollis ENSFALG00000005506 I 0.743
ENSGMOG00000003945 Gadus morhua ENSGMOG00000003945 I 0.740
irf8 Gasterosteus aculeatus ENSGACG00000015958 I 0.740
ENSONIG00000005631 Oreochromis niloticus ENSONIG00000005631 I 0.740
Aan_R015695 Calypte anna Aan_R015695 I 0.737
irf10 Gasterosteus aculeatus ENSGACG00000015123 I 0.733
ENSGALG00000006448 Gallus gallus ENSGALG00000006448 I 0.733
ENSPSIG00000003518 Pelodiscus sinensis ENSPSIG00000003518 I 0.732
irf8 Tetraodon nigroviridis ENSTNIG00000009283 I 0.724
irf10 Tetraodon nigroviridis ENSTNIG00000012613 I 0.724
ENSLACG00000004633 Latimeria chalumnae ENSLACG00000004633 I 0.721
irf9 Tetraodon nigroviridis ENSTNIG00000008698 I 0.721
irf10 Takifugu rubripes ENSTRUG00000002917 I 0.721
ENSTNIG00000002469 Tetraodon nigroviridis ENSTNIG00000002469 I 0.714
ENSFCAG00000029870 Felis catus ENSFCAG00000029870 I 0.714
ENSAMXG00000004911 Astyanax mexicanus ENSAMXG00000004911 I 0.713
ENSSSCG00000025716 Sus scrofa ENSSSCG00000025716 I 0.712
irf10 Xenopus tropicalis XB-GENE-1033046 I 0.705
ENSONIG00000017148 Oreochromis niloticus ENSONIG00000017148 I 0.705
ENSMODG00000019483 Monodelphis domestica ENSMODG00000019483 I 0.705
ENSCAFG00000007099 Canis familiaris ENSCAFG00000007099 I 0.705
ENSLAFG00000030530 Loxodonta africana ENSLAFG00000030530 I 0.705
irf9 Danio rerio ENSDARG00000016457 I 0.702