Irf5 (Mus musculus)
IRF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00605 (IRF) IPR001346 ENSMUSG00000029771 T244222_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Irf5
M00177_2.00
Mus musculus
NNNHGADASH

DSTHTCDNNN
PBM
Badis et al.(2009)
Irf5_3874
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
IRF5
M03332_2.00
Homo sapiens
YCGAAACCGAAMCY

RGKTTCGGTTTCGR
SELEX
Jolma et al.(2013)
IRF5_1
0.984 0.984
IRF5
M03333_2.00
Homo sapiens
HACCGAAACYV

BRGTTTCGGTD
SELEX
Jolma et al.(2013)
IRF5_2
0.984 0.984
IRF5
M05535_2.00
Homo sapiens
NCGAAACCGAWACH

DGTWTCGGTTTCGN
SELEX
Yin et al.(2017)
IRF5_eDBD_HT-SELEX
0.971 0.971
IRF5
M05537_2.00
Homo sapiens
NCGAAACCGAAACY

RGTTTCGGTTTCGN
SELEX
Yin et al.(2017)
IRF5_FL_HT-SELEX
0.971 0.971
IRF5
M10884_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$IRF5_Q3
0.971 0.971
IRF5
M05536_2.00
Homo sapiens
NYGAWACYGAWACH

DGTWTCRGTWTCRN
SELEX
Yin et al.(2017)
IRF5_eDBD_Methyl-HT-SELEX
0.971 0.971
IRF5
M05538_2.00
Homo sapiens
NYGAAACCGAWACY

RGTWTCGGTTTCRN
SELEX
Yin et al.(2017)
IRF5_FL_Methyl-HT-SELEX
0.984 0.984
IRF5
M02256_2.00
Oryctolagus cuniculus
NHCGAAACYN

NRGTTTCGDN
PBM
Weirauch et al.(2014)
pTH9272
0.953 0.953
IRF6
M02253_2.00
Gallus gallus
NNMCNAAWNN

NNWTTNGKNN
PBM
Weirauch et al.(2014)
pTH9178
0.734 0.734
IRF6
M02254_2.00
Meleagris gallopavo
NRNCGAWACY

RGTWTCGNYN
PBM
Weirauch et al.(2014)
pTH9210
0.734 0.734
irf5.L
M02260_2.00
Xenopus laevis
VNCGADACHN

NDGTHTCGNB
PBM
Weirauch et al.(2014)
pTH9367
0.724 0.724
irf6.2
M02259_2.00
Xenopus tropicalis
NVNHGAWACH

DGTWTCDNBN
PBM
Weirauch et al.(2014)
pTH9302
0.705 0.705
For this family, TFs with SR scores > 0.700 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00177_2.00 IRF 15 120

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000004392 IRF 16 121
ENSMUSP00000126273 IRF 16 121
ENSMUSP00000127021 IRF 16 121
ENSMUSP00000130548 IRF 16 80

Links

Other IRF family TFs
Other Mus musculus TFs

75 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
Irf5 Rattus norvegicus ENSRNOG00000007437 I 1.000
ENSPANG00000018384 Papio anubis ENSPANG00000018384 I 0.990
IRF5 Macaca mulatta ENSMMUG00000018478 I 0.990
ENSCSAG00000009970 Chlorocebus sabaeus ENSCSAG00000009970 I 0.990
ENSP00000349770 Macaca fascicularis ENSP00000349770 I 0.990
IRF5 Homo sapiens ENSG00000128604 D 0.984
IRF5 Callithrix jacchus ENSCJAG00000018061 I 0.984
ENSOARG00000003908 Ovis aries ENSOARG00000003908 I 0.981
ENSP00000349770-D1 Bos grunniens ENSP00000349770-D1 I 0.981
IRF5 Bos taurus ENSBTAG00000004989 I 0.971
ENSPPYG00000017989 Pongo abelii ENSPPYG00000017989 I 0.971
IRF5 Pan troglodytes ENSPTRG00000019675 I 0.971
ENSNLEG00000012454 Nomascus leucogenys ENSNLEG00000012454 I 0.971
IRF5 Equus caballus ENSECAG00000009902 I 0.971
Irf5 Dipodomys ordii ENSDORG00000010627 I 0.971
IRF5 Gorilla gorilla ENSGGOG00000012013 I 0.971
IRF5 Microcebus murinus ENSMICG00000000138 I 0.969
IRF5 Ochotona princeps ENSOPRG00000006148 I 0.969
IRF5 Sus scrofa ENSSSCG00000016573 I 0.969
ENSSTOG00000004858 Ictidomys tridecemlineatus ENSSTOG00000004858 I 0.969
IRF5 Felis catus ENSFCAG00000000956 I 0.969
IRF5 Echinops telfairi ENSETEG00000002100 I 0.959
IRF5 Cavia porcellus ENSCPOG00000000246 I 0.953
ENSMPUG00000006034 Mustela putorius furo ENSMPUG00000006034 I 0.953
ENSAMEG00000005109 Ailuropoda melanoleuca ENSAMEG00000005109 I 0.953
IRF5 Oryctolagus cuniculus ENSOCUG00000010101 D 0.952
IRF5 Loxodonta africana ENSLAFG00000021568 I 0.952
IRF5 Erinaceus europaeus ENSEEUG00000014653 I 0.946
Myotis_brandtii_IRF5_10012830 Myotis brandtii Myotis_brandtii_IRF5_10012830 I 0.943
IRF5 Canis familiaris ENSCAFG00000001611 I 0.943
IRF5 Myotis lucifugus ENSMLUG00000001406 I 0.943
ENSMEUG00000002435 Macropus eugenii ENSMEUG00000002435 I 0.924
IRF5 Dasypus novemcinctus ENSDNOG00000013370 I 0.914
IRF5 Monodelphis domestica ENSMODG00000014710 I 0.914
ENSSHAG00000006683 Sarcophilus harrisii ENSSHAG00000006683 I 0.905
IRF5 Ornithorhynchus anatinus ENSOANG00000011449 I 0.895
IRF5 Pteropus vampyrus ENSPVAG00000015756 I 0.884
IRF5 Otolemur garnettii ENSOGAG00000009608 I 0.867
Alligator_sinensis_CCG004564.1 Alligator sinensis Alligator_sinensis_CCG004564.1 I 0.838
Pvit_14327 Pogona vitticeps Pvit_14327 I 0.828
Cmyd_10002838 Chelonia mydas Cmyd_10002838 I 0.819
ENSLACG00000005750 Latimeria chalumnae ENSLACG00000005750 I 0.766
ENSONIG00000007600 Oreochromis niloticus ENSONIG00000007600 I 0.762
irf5 Danio rerio ENSDARG00000045681 I 0.752
irf5 Gasterosteus aculeatus ENSGACG00000000695 I 0.743
irf5 Takifugu rubripes ENSTRUG00000000641 I 0.743
ENSAPLG00000006203 Anas platyrhynchos ENSAPLG00000006203 I 0.743
ENSGMOG00000007264 Gadus morhua ENSGMOG00000007264 I 0.740
ENSFALG00000000504 Ficedula albicollis ENSFALG00000000504 I 0.737
irf5.L Xenopus laevis XB-GENE-998629 D 0.734
ENSLOCG00000015563 Lepisosteus oculatus ENSLOCG00000015563 I 0.733
ENSPFOG00000013528 Poecilia formosa ENSPFOG00000013528 I 0.733
ENSXMAG00000013056 Xiphophorus maculatus ENSXMAG00000013056 I 0.733
ENSAPLG00000009319 Anas platyrhynchos ENSAPLG00000009319 I 0.724
Afo_R001981 Aptenodytes forsteri Afo_R001981 I 0.724
Alligator_sinensis_CCG003696.1 Alligator sinensis Alligator_sinensis_CCG003696.1 I 0.724
Alligator_sinensis_CCG015719.1 Alligator sinensis Alligator_sinensis_CCG015719.1 I 0.724
IRF6 Taeniopygia guttata ENSTGUG00000001485 I 0.724
IRF6 Meleagris gallopavo ENSMGAG00000004431 D 0.724
irf5 Tetraodon nigroviridis ENSTNIG00000003346 I 0.724
IRF6 Gallus gallus ENSGALG00000001405 D 0.724
IRF6 Sus scrofa ENSSSCG00000015612 I 0.723
irf6.2.L Xenopus laevis XB-GENE-5910427 I 0.719
Pvit_15428 Pogona vitticeps Pvit_15428 I 0.719
irf6.S Xenopus laevis XB-GENE-876421 I 0.714
irf5 Xenopus tropicalis XB-GENE-998624 I 0.714
ENSLACG00000018600 Latimeria chalumnae ENSLACG00000018600 I 0.714
ENSPSIG00000003597 Pelodiscus sinensis ENSPSIG00000003597 I 0.714
IRF6 Ornithorhynchus anatinus ENSOANG00000013718 I 0.705
ENSMEUG00000014941 Macropus eugenii ENSMEUG00000014941 I 0.705
IRF6 Anolis carolinensis ENSACAG00000005931 I 0.705
Cmyd_10010684 Chelonia mydas Cmyd_10010684 I 0.705
IRF6 Monodelphis domestica ENSMODG00000002539 I 0.705
irf6.2 Xenopus tropicalis XB-GENE-5910331 D 0.705