ENSBTAP00000044267-D1 (Bos grunniens)
IRF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00605 (IRF) IPR001346 ENSBTAP00000044267-D1 T244532_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
IRF9
M02258_2.00
Sus scrofa
WNYGAAASY

RSTTTCRNW
PBM
Weirauch et al.(2014)
pTH9287
0.913 0.913
IRF9
M02257_2.00
Ochotona princeps
DNYRAAAVND

HNBTTTYRNH
PBM
Weirauch et al.(2014)
pTH9337
0.875 0.875
Irf9
M00173_2.00
Mus musculus
NNNRAAANN

NNTTTYNNN
PBM
Badis et al.(2009)
Isgf3g_2853
0.788 0.788
Irf9
M09240_2.00
Mus musculus
GAAABHGAAAYT

ARTTTCDVTTTC
Misc
Kulakovskiy et al.(2013)
IRF9_MOUSE.H11MO.0.C
0.788 0.788
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSBTAP00000044267-D1 IRF 46 150

Links

Other IRF family TFs
Other Bos grunniens TFs

37 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSAMEG00000016347 Ailuropoda melanoleuca ENSAMEG00000016347 I 0.923
ENSCSAG00000016071 Chlorocebus sabaeus ENSCSAG00000016071 I 0.865
ENSMEUG00000010784 Macropus eugenii ENSMEUG00000010784 I 0.846
ENSMMUG00000012474 Macaca mulatta ENSMMUG00000012474 I 0.865
ENSMPUG00000005961 Mustela putorius furo ENSMPUG00000005961 I 0.923
ENSNLEG00000015294 Nomascus leucogenys ENSNLEG00000015294 I 0.856
ENSOARG00000019201 Ovis aries ENSOARG00000019201 I 0.962
ENSP00000380073 Macaca fascicularis ENSP00000380073 I 0.865
ENSPPYG00000005686 Pongo abelii ENSPPYG00000005686 I 0.865
ENSSHAG00000001872 Sarcophilus harrisii ENSSHAG00000001872 I 0.837
ENSSTOG00000023450 Ictidomys tridecemlineatus ENSSTOG00000023450 I 0.846
ENSTSYG00000007445 Tarsius syrichta ENSTSYG00000007445 I 0.846
IRF9 Procavia capensis ENSPCAG00000015500 I 0.863
IRF9 Pan troglodytes ENSPTRG00000034494 I 0.856
IRF9 Pteropus vampyrus ENSPVAG00000007716 I 0.923
Irf9 Rattus norvegicus ENSRNOG00000019478 I 0.808
IRF9 Felis catus ENSFCAG00000018849 I 0.923
IRF9 Sus scrofa ENSSSCG00000002002 D 0.913
irf9 Takifugu rubripes ENSTRUG00000017722 I 0.702
IRF9 Tursiops truncatus ENSTTRG00000008624 I 0.912
irf9 Oryzias latipes ENSORLG00000013335 I 0.712
IRF9 Ochotona princeps ENSOPRG00000018909 D 0.875
IRF9 Otolemur garnettii ENSOGAG00000026670 I 0.846
IRF9 Homo sapiens ENSG00000213928 D 0.856
IRF9 Gorilla gorilla ENSGGOG00000016046 I 0.856
IRF9 Loxodonta africana ENSLAFG00000026182 I 0.885
IRF9 Equus caballus ENSECAG00000024429 I 0.923
IRF9 Myotis lucifugus ENSMLUG00000025255 I 0.904
IRF9 Cavia porcellus ENSCPOG00000026474 I 0.865
IRF9 Monodelphis domestica ENSMODG00000003368 I 0.837
IRF9 Callithrix jacchus ENSCJAG00000007065 I 0.885
Irf9 Mus musculus ENSMUSG00000002325 D 0.788
IRF9 Canis familiaris ENSCAFG00000012007 I 0.923
IRF9 Bos taurus ENSBTAG00000005816 I 1.000
IRF9 Oryctolagus cuniculus ENSOCUG00000028186 I 0.856
Myotis_brandtii_IRF9_10003711 Myotis brandtii Myotis_brandtii_IRF9_10003711 I 0.904
Pvit_14926 Pogona vitticeps Pvit_14926 I 0.712