|
snap_masked-pag1_scaffold_483-abinit-gene-0.32
(Pythium aphanidermatum)
MADS box
|
TF Information |
Pfam ID |
Interpro ID |
Gene ID |
CIS-BP ID |
Sequence source |
Animal TF db |
PF00319 (SRF-TF) |
IPR002100 |
snap_masked-pag1_scaffold_483-abinit-gene-0.32 |
T256283_2.00 |
Ensembl (2018-Dec-8) |
Link out |
NCBI Gene Info:This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] |
Directly determined binding motifs |
Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR Score |
DBD Identity |
No direct experiments |
|
|
|
|
|
Motifs from related TFs |
Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR Score |
DBD Identity |
MEF2A
M03340_2.00 |
Homo sapiens |
KCTAWAAATAGM |
KCTATTTWTAGM |
SELEX
Jolma et al.(2013)
MEF2A_1
|
0.750
|
0.750
|
MEF2C
M02745_2.00 |
Homo sapiens |
TWCTAWAAATAG |
CTATTTWTAGWA |
SELEX
Jolma et al.(2010)
MEF2C_dimer
|
0.750
|
0.750
|
MEF2C
M05551_2.00 |
Homo sapiens |
CYWWATWWGG |
CCWWATWWRG |
SELEX
Yin et al.(2017)
MEF2C_FL_HT-SELEX
|
0.750
|
0.750
|
MEF2C
M08149_2.00 |
Homo sapiens |
NDDMYAAAAATAGMH |
DKCTATTTTTRKHHN |
ChIP-seq
Mathelier et al.(2014)
MA0497.1
|
0.750
|
0.750
|
MEF2A
M07979_2.00 |
Homo sapiens |
NDDHYAAAAATARHH |
DDYTATTTTTRDHHN |
ChIP-seq
Gerstein et al.(2012)
GM12878_MEF2A_HudsonAlpha
|
0.750
|
0.750
|
MEF2C
M07980_2.00 |
Homo sapiens |
NDDYYAAAAATAGHH |
DDCTATTTTTRRHHN |
ChIP-seq
Gerstein et al.(2012)
GM12878_MEF2C_HudsonAlpha
|
0.750
|
0.750
|
Mef2
M08214_2.00 |
Drosophila melanogaster |
YTAWWWWTAR |
YTAWWWWTAR |
ChIP-seq
Contrino et al.(2012)
Mf26
|
0.750
|
0.750
|
MEF2A
M08212_2.00 |
Homo sapiens |
CTAWWWWTAG |
CTAWWWWTAG |
ChIP-seq
Contrino et al.(2012)
Mv88
|
0.750
|
0.750
|
MEF2A
M08213_2.00 |
Homo sapiens |
AAAATAGM |
KCTATTTT |
ChIP-seq
Contrino et al.(2012)
Mv90
|
0.750
|
0.750
|
MEF2A
M09247_2.00 |
Homo sapiens |
DYYAAAAATAGMH |
DKCTATTTTTRRH |
Misc
Kulakovskiy et al.(2013)
MEF2A_HUMAN.H11MO.0.A
|
0.750
|
0.750
|
MEF2C
M09248_2.00 |
Homo sapiens |
DYYAAAAATARMH |
DKYTATTTTTRRH |
Misc
Kulakovskiy et al.(2013)
MEF2C_HUMAN.H11MO.0.A
|
0.750
|
0.750
|
Mef2a
M09255_2.00 |
Mus musculus |
DDCYAWAAATARMH |
DKYTATTTWTRGHH |
Misc
Kulakovskiy et al.(2013)
MEF2A_MOUSE.H11MO.0.A
|
0.750
|
0.750
|
Mef2c
M09253_2.00 |
Mus musculus |
DDMYAAAAATAGMHN |
NDKCTATTTTTRKHH |
Misc
Kulakovskiy et al.(2013)
MEF2C_MOUSE.H11MO.0.A
|
0.750
|
0.750
|
MEF2C
M09597_2.00 |
Homo sapiens |
DHYWDAAATARM |
KYTATTTHWRDH |
Misc
Heinz et al.(2010)
GM12878-Mef2c_GSE32465
|
0.750
|
0.750
|
Mef2a
M09599_2.00 |
Mus musculus |
CYNDAAATAG |
CTATTTHNRG |
Misc
Heinz et al.(2010)
HL1-Mef2a.biotin_GSE21529
|
0.750
|
0.750
|
MEF2A
M10933_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$AMEF2_Q6
|
0.750
|
0.750
|
MEF2A
M10934_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$HMEF2_Q6
|
0.750
|
0.750
|
MEF2A
M10935_2.00 |
Homo sapiens |
BTCTAAAAATAACYCY |
RGRGTTATTTTTAGAV |
Transfac
Matys et al.(2006)
V$MEF2_01
|
0.750
|
0.750
|
MEF2A
M10936_2.00 |
Homo sapiens |
BNNNDDDCTAWAAATAGMHNNN |
NNNDKCTATTTWTAGHHHNNNV |
Transfac
Matys et al.(2006)
V$MEF2_02
|
0.750
|
0.750
|
MEF2A
M10937_2.00 |
Homo sapiens |
NNNNDWKCTAWAAATAGMHHNN |
NNDDKCTATTTWTAGMWHNNNN |
Transfac
Matys et al.(2006)
V$MEF2_03
|
0.750
|
0.750
|
MEF2A
M10938_2.00 |
Homo sapiens |
NVTGTTRCTAWAAATAGAAHHN |
NDDWTCTATTTWTAGYAACABN |
Transfac
Matys et al.(2006)
V$MEF2_04
|
0.750
|
0.750
|
MEF2A
M10939_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$MEF2A_05
|
0.750
|
0.750
|
MEF2A
M10940_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$MEF2A_Q6
|
0.750
|
0.750
|
MEF2C
M10945_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$MEF2C_02
|
0.750
|
0.750
|
MEF2C
M10946_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$MEF2C_Q4
|
0.750
|
0.750
|
MEF2A
M10941_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$MEF2_Q6_02
|
0.750
|
0.750
|
MEF2A
M10942_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$MMEF2_Q6
|
0.750
|
0.750
|
MEF2A
M10943_2.00 |
Homo sapiens |
NDKCTAWAAATAGMHH |
DDKCTATTTWTAGMHN |
Transfac
Matys et al.(2006)
V$RSRFC4_01
|
0.750
|
0.750
|
MEF2A
M10944_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$RSRFC4_Q2
|
0.750
|
0.750
|
MEF2C
M05552_2.00 |
Homo sapiens |
CYWWATWWGG |
CCWWATWWRG |
SELEX
Yin et al.(2017)
MEF2C_FL_Methyl-HT-SELEX
|
0.750
|
0.750
|
MEF2B
M03344_2.00 |
Homo sapiens |
RCTAWAAATAGM |
KCTATTTWTAGY |
SELEX
Jolma et al.(2013)
MEF2B_1
|
0.729
|
0.729
|
MEF2D
M03343_2.00 |
Homo sapiens |
DCTAWAAATAGM |
KCTATTTWTAGH |
SELEX
Jolma et al.(2013)
MEF2D_1
|
0.729
|
0.729
|
MEF2B
M05557_2.00 |
Homo sapiens |
CYNDWWWHGG |
CCDWWWHNRG |
SELEX
Yin et al.(2017)
MEF2B_eDBD_HT-SELEX
|
0.729
|
0.729
|
MEF2B
M05559_2.00 |
Homo sapiens |
CCVDWTATGGTAACA |
TGTTACCATAWHBGG |
SELEX
Yin et al.(2017)
MEF2B_FL_HT-SELEX
|
0.729
|
0.729
|
MEF2D
M05555_2.00 |
Homo sapiens |
CYWWATWWGG |
CCWWATWWRG |
SELEX
Yin et al.(2017)
MEF2D_eDBD_HT-SELEX
|
0.729
|
0.729
|
MEF2B
M09251_2.00 |
Homo sapiens |
CYWAAAATAGHHHH |
DDDDCTATTTTWRG |
Misc
Kulakovskiy et al.(2013)
MEF2B_HUMAN.H11MO.0.A
|
0.729
|
0.729
|
MEF2D
M09250_2.00 |
Homo sapiens |
CTAWAAATAGMH |
DKCTATTTWTAG |
Misc
Kulakovskiy et al.(2013)
MEF2D_HUMAN.H11MO.0.A
|
0.729
|
0.729
|
Mef2d
M09252_2.00 |
Mus musculus |
DDCTAWAAATAGMH |
DKCTATTTWTAGHH |
Misc
Kulakovskiy et al.(2013)
MEF2D_MOUSE.H11MO.0.A
|
0.729
|
0.729
|
MEF2D
M10957_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$MEF2D_Q4
|
0.729
|
0.729
|
MEF2B
M05558_2.00 |
Homo sapiens |
CYWWWWWNGG |
CCNWWWWWRG |
SELEX
Yin et al.(2017)
MEF2B_eDBD_Methyl-HT-SELEX
|
0.729
|
0.729
|
MEF2B
M05560_2.00 |
Homo sapiens |
CCVDATATGGTAACR |
YGTTACCATATHBGG |
SELEX
Yin et al.(2017)
MEF2B_FL_Methyl-HT-SELEX
|
0.729
|
0.729
|
MEF2D
M05556_2.00 |
Homo sapiens |
CYWWATWWGG |
CCWWATWWRG |
SELEX
Yin et al.(2017)
MEF2D_eDBD_Methyl-HT-SELEX
|
0.729
|
0.729
|
Solyc05g012020.2
M10986_2.00 |
Solanum lycopersicum |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
P$RIN_01
|
0.708
|
0.708
|
Solyc05g012020.2
M10987_2.00 |
Solanum lycopersicum |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
P$RIN_Q2_01
|
0.708
|
0.708
|
Solyc05g012020.2
M10988_2.00 |
Solanum lycopersicum |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
P$RIN_Q2
|
0.708
|
0.708
|
Mef2b
M10958_2.00 |
Mus musculus |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$MEF2B_02
|
0.708
|
0.708
|
For this family, TFs with SR scores > 0.700 will likely have a similar motif |