HHAL001485-PA (Halyomorpha halys)
MADS box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00319 (SRF-TF) IPR002100 HHAL001485-PA T259222_2.00 Misc (2018-Jan-19)
NCBI Gene Info:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
bs
M03915_2.00 		Drosophila melanogaster
NCCWTATAWGGN
NCCWTATAWGGN		 SELEX
Nitta et al.(2015)
bs_1 		0.897 0.897
bs
M03916_2.00 		Drosophila melanogaster
NCCWTAHAWGGH
DCCWTDTAWGGN		 SELEX
Nitta et al.(2015)
bs_2 		0.897 0.897
srfA
M02283_2.00 		Dictyostelium discoideum
MYDWWWNNRD
HYNNWWWHRK		 PBM
Weirauch et al.(2014)
pTH5539 		0.862 0.862
Srf
M00178_2.00 		Mus musculus
NNDDWWHHNN
NNDDWWHHNN		 PBM
Badis et al.(2009)
Srf_3509 		0.862 0.862
SRF
M03341_2.00 		Homo sapiens
DCCWTATATGGT
ACCATATAWGGH		 SELEX
Jolma et al.(2013)
SRF_1 		0.862 0.862
SRF
M03342_2.00 		Homo sapiens
TKHCCWTATATGGKMA
TKMCCATATAWGGDMA		 SELEX
Jolma et al.(2013)
SRF_2 		0.862 0.862
SRF
M05553_2.00 		Homo sapiens
CCNTANAWGG
CCWTNTANGG		 SELEX
Yin et al.(2017)
SRF_eDBD_HT-SELEX 		0.862 0.862
SRF
M07981_2.00 		Homo sapiens
NNNWDNCCAWAWAWGGNVD
HBNCCWTWTWTGGNHWNNN		 ChIP-seq
Gerstein et al.(2012)
GM12878_SRF_HudsonAlpha 		0.862 0.862
SRF
M07982_2.00 		Homo sapiens
CCAWATAAGGNMAD
HTKNCCTTATWTGG		 ChIP-seq
Gerstein et al.(2012)
H1-hESC_SRF_HudsonAlpha 		0.862 0.862
SRF
M07983_2.00 		Homo sapiens
NNWNNCCAWAWAWGGNVD
HBNCCWTWTWTGGNNWNN		 ChIP-seq
Gerstein et al.(2012)
HepG2_SRF_HudsonAlpha 		0.862 0.862
SRF
M07984_2.00 		Homo sapiens
GNCCAWATADGGHMANN
NNTKDCCHTATWTGGNC		 ChIP-seq
Gerstein et al.(2012)
K562_SRF_HudsonAlpha 		0.862 0.862
SRF
M09249_2.00 		Homo sapiens
HNWBVCCAWAWAWGGNRR
YYNCCWTWTWTGGBVWND		 Misc
Kulakovskiy et al.(2013)
SRF_HUMAN.H11MO.0.A 		0.862 0.862
Srf
M09254_2.00 		Mus musculus
NWDVCCAWAWAWGGVMR
YKBCCWTWTWTGGBHWN		 Misc
Kulakovskiy et al.(2013)
SRF_MOUSE.H11MO.0.A 		0.862 0.862
Srf
M09598_2.00 		Mus musculus
CCWWATWWGGNH
DNCCWWATWWGG		 Misc
Heinz et al.(2010)
PUER-Srf_Sullivan_et_al. 		0.862 0.862
SRF
M10947_2.00 		Homo sapiens
MNBWCCWTATAWGGGCAT
ATGCCCWTATAWGGWVNK		 Transfac
Matys et al.(2006)
V$SRF_01 		0.862 0.862
SRF
M10948_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SRF_02 		0.862 0.862
SRF
M10949_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SRF_03 		0.862 0.862
SRF
M10950_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SRF_09 		0.862 0.862
SRF
M10951_2.00 		Homo sapiens
DCCWTATAWGGVSHB
VDSBCCWTATAWGGH		 Transfac
Matys et al.(2006)
V$SRF_C 		0.862 0.862
SRF
M10952_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SRF_Q3 		0.862 0.862
SRF
M10953_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SRF_Q4 		0.862 0.862
SRF
M10954_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SRF_Q5_01 		0.862 0.862
SRF
M10955_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SRF_Q5_02 		0.862 0.862
SRF
M10956_2.00 		Homo sapiens
BNCCAWATAWGGVN
NBCCWTATWTGGNV		 Transfac
Matys et al.(2006)
V$SRF_Q6 		0.862 0.862
SRF
M05554_2.00 		Homo sapiens
CCNTAYAWGG
CCWTRTANGG		 SELEX
Yin et al.(2017)
SRF_eDBD_Methyl-HT-SELEX 		0.862 0.862
unc-120
M00684_2.00 		Caenorhabditis elegans
CHWAWWDGG
CCHWWTWDG		 PBM
Narasimhan et al.(2015)
pTH10822 		0.828 0.828
MCM1
M01558_2.00 		Saccharomyces cerevisiae
YNNWWNNRGN
NCYNNWWNNR		 PBM
Zhu et al.(2009)
Mcm1 		0.724 0.724
MCM1
M08589_2.00 		Saccharomyces cerevisiae
HNHTWCCBDWWHVGGAHDHN
NDHDTCCBDWWHVGGWADND		 Misc
DeBoer et al.(2011)
YMR043W_831 		0.724 0.724
MCM1
M10990_2.00 		Saccharomyces cerevisiae
WNDCCYAAWNNGGWMW
WKWCCNNWTTRGGHNW		 Transfac
Matys et al.(2006)
F$MCM1_01 		0.724 0.724
MCM1
M10991_2.00 		Saccharomyces cerevisiae Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
F$MCM1_02 		0.724 0.724
MCM1
M10992_2.00 		Saccharomyces cerevisiae Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
F$MCM1_Q6 		0.724 0.724
MCM1
M08458_2.00 		Saccharomyces cerevisiae
TTCCYRAWNNGG
CCNNWTYRGGAA		 COMPILED
Mathelier et al.(2014)
MA0331.1 		0.724 0.724
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
HHAL001485-PA MADS box 55 83

Links

Other MADS box family TFs
Other Halyomorpha halys TFs

143 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
SINV23954 Solenopsis invicta SINV23954 I 1.000
SRF Taeniopygia guttata ENSTGUG00000004738 I 0.963
ASTEI07120 Anopheles stephensi ASTEI07120 I 0.963
Aan_R005414 Calypte anna Aan_R005414 I 0.963
ENSMLUG00000008828 Myotis lucifugus ENSMLUG00000008828 I 0.963
AFUN006147 Anopheles funestus AFUN006147 I 0.963
ACHR000964 Anopheles christyi ACHR000964 I 0.963
SRF Loxodonta africana ENSLAFG00000010278 I 0.963
ENSFALG00000000878 Ficedula albicollis ENSFALG00000000878 I 0.963
MESCA001358 Megaselia scalaris MESCA001358 I 0.963
SRF Cavia porcellus ENSCPOG00000022327 I 0.963
Gfo_R009695 Geospiza fortis Gfo_R009695 I 0.963
Afo_R000461 Aptenodytes forsteri Afo_R000461 I 0.963
ADIR000346 Anopheles dirus ADIR000346 I 0.963
ADAC008363 Anopheles darlingi ADAC008363 I 0.963
ASIS007770 Anopheles sinensis ASIS007770 I 0.963
Brh_R011000 Buceros rhinoceros Brh_R011000 I 0.962
ENSOPRG00000002509 Ochotona princeps ENSOPRG00000002509 I 0.962
SRF Gorilla gorilla ENSGGOG00000006293 I 0.962
SRF Vicugna pacos ENSVPAG00000008912 I 0.962
ENSGMOG00000001540 Gadus morhua ENSGMOG00000001540 I 0.962
CLEC013390 Cimex lectularius CLEC013390 I 0.929
TELCIR_03792 Teladorsagia circumcincta TELCIR_03792 I 0.929
MCINX015635 Melitaea cinxia MCINX015635 I 0.929
AARA006325 Anopheles arabiensis AARA006325 I 0.929
TELCIR_12851 Teladorsagia circumcincta TELCIR_12851 I 0.926
GK22205 Drosophila willistoni FBgn0224190 I 0.897
GE14398 Drosophila yakuba FBgn0232006 I 0.897
GB47234 Apis mellifera GB47234 I 0.897
D917_02561 Trichinella nativa D917_02561 I 0.897
D918_07967 Trichuris suis D918_07967 I 0.897
HMEL017830 Heliconius melpomene HMEL017830 I 0.897
ISCW019966 Ixodes scapularis ISCW019966 I 0.897
AATE011966 Anopheles atroparvus AATE011966 I 0.897
AMIN001258 Anopheles minimus AMIN001258 I 0.897
L798_08800 Zootermopsis nevadensis L798_08800 I 0.897
LotgiG59850 Lottia gigantea LotgiG59850 I 0.897
GJ21595 Drosophila virilis FBgn0208714 I 0.897
LCUP011663 Lucilia cuprina LCUP011663 I 0.897
AQUA001308 Anopheles quadriannulatus AQUA001308 I 0.897
ASIS013674 Anopheles sinensis ASIS013674 N 0.897
fgenesh2_pg.scaffold_196000035 Branchiostoma floridae fgenesh2_pg.scaffold_196000035 I 0.897
Sakowv30019106m.g Saccoglossus kowalevskii Sakowv30019106m.g I 0.897
fgenesh2_pg.scaffold_8000100 Branchiostoma floridae fgenesh2_pg.scaffold_8000100 I 0.897
Hsal_11632--XP_001120126.1_APIME Harpegnathos saltator Hsal_11632--XP_001120126.1_APIME I 0.897
Cflo_11261--XP_001120126.1_APIME Camponotus floridanus Cflo_11261--XP_001120126.1_APIME I 0.897
SMAR003014 Strigamia maritima SMAR003014 I 0.897
AALB009948 Anopheles albimanus AALB009948 I 0.897
MDOA002443 Musca domestica MDOA002443 I 0.897
SPU_027774 Strongylocentrotus purpuratus SPU_027774 I 0.897
BGLB003854 Biomphalaria glabrata BGLB003854 I 0.897
TC004911 Tribolium castaneum TC004911 I 0.897
NV18787 Nasonia vitripennis NV18787 I 0.897
GL20046 Drosophila persimilis FBgn0157643 I 0.897
CGI_10019446 Crassostrea gigas CGI_10019446 I 0.897
CapteG221100 Capitella teleta CapteG221100 I 0.897
BGIBMGA001384 Bombyx mori BGIBMGA001384 I 0.897
SBAD_0000850501 Soboliphyme baturini SBAD_0000850501 I 0.897
GD11852 Drosophila simulans FBgn0183591 I 0.897
ACOM041693 Anopheles coluzzii ACOM041693 I 0.897
DAPPUDRAFT_8703 Daphnia pulex DAPPUDRAFT_8703 I 0.897
TMUE_s0092001100 Trichuris muris TMUE_s0092001100 I 0.897
AGAP010512 Anopheles gambiae AGAP010512 I 0.897
TTRE_0000468501 Trichuris trichiura TTRE_0000468501 I 0.897
AEPI007010 Anopheles epiroticus AEPI007010 I 0.897
AFAF013563 Anopheles farauti AFAF013563 I 0.897
AAEL008720 Aedes aegypti AAEL008720 I 0.897
AAEL010926 Aedes aegypti AAEL010926 I 0.897
ACYPI002973 Acyrthosiphon pisum ACYPI002973 I 0.897
ACEP12187 Atta cephalotes ACEP12187 I 0.897
EFV60876 Trichinella spiralis EFV60876 I 0.897
ACUA004576 Anopheles culicifacies ACUA004576 I 0.897
GF11392 Drosophila ananassae FBgn0088432 I 0.897
GA17433 Drosophila pseudoobscura FBgn0077446 I 0.897
bs Drosophila melanogaster FBgn0004101 D 0.897
ENSPFOG00000018770 Poecilia formosa ENSPFOG00000018770 I 0.897
GG22961 Drosophila erecta FBgn0115118 I 0.897
GH20989 Drosophila grimshawi FBgn0128451 I 0.897
GM11854 Drosophila sechellia FBgn0166795 I 0.897
ENSOARG00000005757 Ovis aries ENSOARG00000005757 I 0.897
GI21322 Drosophila mojavensis FBgn0144052 I 0.897
O9G_005180 Rozella allomycis O9G_005180 I 0.893
Hba_21368 Heterorhabditis bacteriophora Hba_21368 I 0.893
SRF Sorex araneus ENSSARG00000003401 I 0.885
SRF Erinaceus europaeus ENSEEUG00000005614 I 0.885
ENSP00000265354 Macaca fascicularis ENSP00000265354 I 0.867
LLOJ005985 Lutzomyia longipalpis LLOJ005985 I 0.867
RSKR_0001102000 Rhabditophanes kr3021 RSKR_0001102000 I 0.862
HPLM_0000743501 Haemonchus placei HPLM_0000743501 I 0.862
Cmyd_10009988 Chelonia mydas Cmyd_10009988 I 0.862
ANCDUO_04431 Ancylostoma duodenale ANCDUO_04431 I 0.862
SPPG_06208 Spizellomyces punctatus SPPG_06208 I 0.862
Ogr17973 Ophisaurus gracilis Ogr17973 I 0.839
srfB Dictyostelium discoideum DDB_G0282835 I 0.828
CJA08385 Caenorhabditis japonica CJA08385 I 0.828
BXY_0217000 Bursaphelenchus xylophilus BXY_0217000 I 0.828
ENSCSAVG00000008682 Ciona savignyi ENSCSAVG00000008682 I 0.828
CpipJ_CPIJ008335 Culex pipiens CpipJ_CPIJ008335 I 0.818
CPIJ008335 Culex quinquefasciatus CPIJ008335 I 0.818
Myotis_brandtii_SRF_10026135 Myotis brandtii Myotis_brandtii_SRF_10026135 I 0.806
gw1.8.565.1 Mucor circinelloides gw1.8.565.1 I 0.793
GLOINDRAFT_82941 Rhizophagus irregularis GLOINDRAFT_82941 I 0.793
DACRYDRAFT_57073 Dacryopinax sp DACRYDRAFT_57073 I 0.793
DI09_81p70 Microsporidia sp DI09_81p70 I 0.793
E5Q_02524 Mixia osmundae E5Q_02524 I 0.793
RO3G_15079 Rhizopus oryzae RO3G_15079 I 0.793
RO3G_07165 Rhizopus oryzae RO3G_07165 I 0.793
RO3G_00948 Rhizopus oryzae RO3G_00948 I 0.793
RO3G_06121 Rhizopus oryzae RO3G_06121 I 0.793
GLOTRDRAFT_42980 Gloeophyllum trabeum GLOTRDRAFT_42980 I 0.793
HelroG137972 Helobdella robusta HelroG137972 I 0.793
estExt_fgeneshMC_pm.C_40429 Mucor circinelloides estExt_fgeneshMC_pm.C_40429 I 0.793
fgeneshPB_pg.1__662 Phycomyces blakesleeanus fgeneshPB_pg.1__662 I 0.793
e_gw1.6.1281.1 Mucor circinelloides e_gw1.6.1281.1 I 0.793
e_gw1.4.1161.1 Mucor circinelloides e_gw1.4.1161.1 I 0.793
PAXRUDRAFT_829045 Paxillus rubicundulus PAXRUDRAFT_829045 I 0.793
e_gw1.1.687.1 Phycomyces blakesleeanus e_gw1.1.687.1 I 0.793
gw1.3.516.1 Phycomyces blakesleeanus gw1.3.516.1 I 0.793
MVLG_04297 Microbotryum violaceum MVLG_04297 I 0.759
CH063_12904 Colletotrichum higginsianum CH063_12904 I 0.759
Cob_05053 Colletotrichum orbiculare Cob_05053 I 0.759
CSUB01_05290 Colletotrichum sublineola CSUB01_05290 I 0.759
CFIO01_12657 Colletotrichum fioriniae CFIO01_12657 I 0.759
CANTEDRAFT_132918 Candida tenuis CANTEDRAFT_132918 I 0.759
SNOG_07763 Stagonospora nodorum SNOG_07763 I 0.759
AWRI1499_3592 Brettanomyces bruxellensis AWRI1499_3592 I 0.759
GLRG_02553 Colletotrichum graminicola GLRG_02553 I 0.759
GGTG_11623 Gaeumannomyces graminis GGTG_11623 I 0.759
fgenesh1_kg.C_scaffold_2000029 Cochliobolus heterostrophus C5 fgenesh1_kg.C_scaffold_2000029 I 0.759
VDAG_01770 Verticillium dahliae VDAG_01770 I 0.759
SNOG_07764 Phaeosphaeria nodorum SNOG_07764 I 0.759
MGG_02773 Magnaporthe oryzae MGG_02773 I 0.759
MAPG_02274 Magnaporthe poae MAPG_02274 I 0.759
PredSwiss_CON2346.1 Pneumocystis carinii PredSwiss_CON2346.1 I 0.759
sr10299 Sporisorium reilianum sr10299 I 0.724
WALSEDRAFT_9958 Wallemia sebi WALSEDRAFT_9958 I 0.724
L893_g14743 Steinernema glaseri L893_g14743 I 0.724
L596_g5274 Steinernema carpocapsae L596_g5274 I 0.724
SNAPOd2T00012736001 Oikopleura dioica SNAPOd2T00012736001 I 0.724
L889_g24087 Steinernema feltiae L889_g24087 I 0.724
L892_g14520 Steinernema scapterisci L892_g14520 I 0.724
J056_002827 Wallemia ichthyophaga J056_002827 I 0.724
L898_g9834 Steinernema monticolum L898_g9834 I 0.724