setdb1b (Danio rerio)
MBD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF01429 (MBD) IPR001739 ENSDARG00000099021 T260108_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable histone methyltransferase activity (H3-K9 specific) and promoter-specific chromatin binding activity. Predicted to be involved in several processes, including Ras protein signal transduction; histone H3-K9 methylation; and regulation of gene expression. Predicted to act upstream of or within chromatin organization and histone lysine methylation. Predicted to be located in chromosome. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autistic disorder and lung cancer. Orthologous to human SETDB1 (SET domain bifurcated histone lysine methyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
SETDB1
M11031_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SETDB1_01 		0.800 0.800
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000136505 MBD 605 679
ENSDARP00000140273 MBD 595 669

Links

Other MBD family TFs
Other Danio rerio TFs

Invalid Input OrderBy

66 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action