Mbd4 (Mus musculus)
MBD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF01429 (MBD) IPR001739 ENSMUSG00000030322 T260277_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA binding activity. Acts upstream of or within intrinsic apoptotic signaling pathway in response to DNA damage; mitotic G2 DNA damage checkpoint signaling; and response to radiation. Located in chromatin; cytoplasm; and nucleus. Is expressed in several structures, including central nervous system; lower urogenital tract; reproductive system; retina; and urethra epithelium. Human ortholog(s) of this gene implicated in colorectal carcinoma; esophagus squamous cell carcinoma; lung cancer; and rheumatoid arthritis. Orthologous to human MBD4 (methyl-CpG binding domain 4, DNA glycosylase). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000032469 MBD 63 136
ENSMUSP00000125619 MBD 42 115

Links

Other MBD family TFs
Other Mus musculus TFs

38 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Mbd4 Rattus norvegicus ENSRNOG00000010919 N 0.865
ENSNLEG00000005337 Nomascus leucogenys ENSNLEG00000005337 N 0.838
ENSPANG00000015047 Papio anubis ENSPANG00000015047 N 0.827
MBD4 Macaca mulatta ENSMMUG00000012723 N 0.827
ENSP00000249910 Macaca fascicularis ENSP00000249910 N 0.827
ENSCSAG00000009037 Chlorocebus sabaeus ENSCSAG00000009037 N 0.827
MBD4 Pteropus vampyrus ENSPVAG00000005238 N 0.824
MBD4 Vicugna pacos ENSVPAG00000004040 N 0.824
MBD4 Gorilla gorilla ENSGGOG00000010698 N 0.824
MBD4 Homo sapiens ENSG00000129071 N 0.824
ENSPPYG00000013417 Pongo abelii ENSPPYG00000013417 N 0.824
MBD4 Pan troglodytes ENSPTRG00000015377 N 0.824
MBD4 Equus caballus ENSECAG00000022106 N 0.813
MBD4 Oryctolagus cuniculus ENSOCUG00000013006 N 0.811
Myotis_brandtii_MBD4_10028283 Myotis brandtii Myotis_brandtii_MBD4_10028283 N 0.811
ENSSTOG00000020663 Ictidomys tridecemlineatus ENSSTOG00000020663 N 0.811
MBD4 Otolemur garnettii ENSOGAG00000010236 N 0.800
MBD4 Loxodonta africana ENSLAFG00000010609 N 0.797
ENSMPUG00000017195 Mustela putorius furo ENSMPUG00000017195 N 0.797
MBD4 Erinaceus europaeus ENSEEUG00000011459 N 0.797
MBD4 Dasypus novemcinctus ENSDNOG00000049619 N 0.797
MBD4 Myotis lucifugus ENSMLUG00000014766 N 0.797
MBD4 Procavia capensis ENSPCAG00000012915 N 0.797
MBD4 Microcebus murinus ENSMICG00000008022 N 0.787
MBD4 Callithrix jacchus ENSCJAG00000017293 N 0.787
MBD4 Canis familiaris ENSCAFG00000004867 N 0.787
ENSAMEG00000004562 Ailuropoda melanoleuca ENSAMEG00000004562 N 0.784
MBD4 Tursiops truncatus ENSTTRG00000011265 N 0.784
MBD4 Felis catus ENSFCAG00000000083 N 0.773
ENSTSYG00000011147 Tarsius syrichta ENSTSYG00000011147 N 0.760
ENSOARG00000014699 Ovis aries ENSOARG00000014699 N 0.733
ENSCPOG00000004970 Cavia porcellus ENSCPOG00000004970 N 0.733
MBD4 Ochotona princeps ENSOPRG00000000473 N 0.733
MBD4 Monodelphis domestica ENSMODG00000006399 N 0.718
MBD4 Bos taurus ENSBTAG00000021645 N 0.716
MBD4 Tupaia belangeri ENSTBEG00000003041 N 0.707
ENSSHAG00000012953 Sarcophilus harrisii ENSSHAG00000012953 N 0.703