MBD-like (Drosophila melanogaster)
MBD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF01429 (MBD) IPR001739 FBgn0027950 T260515_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables several functions, including histone deacetylase binding activity; methyl-CpG binding activity; and protein homodimerization activity. Involved in chromosome condensation and negative regulation of transcription, DNA-templated. Located in nucleus and polytene chromosome. Part of NuRD complex. Is expressed in several structures, including gonad. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to several human genes including MBD3 (methyl-CpG binding domain protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0081546 MBD 9 126
FBpp0081547 MBD 9 100
FBpp0081547 MBD 126 239
FBpp0306716 MBD 9 101
FBpp0306716 MBD 127 240

Links

Other MBD family TFs
Other Drosophila melanogaster TFs

Invalid Input OrderBy

13 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action