NCBI Gene Info:Enables several functions, including histone deacetylase binding activity; methyl-CpG binding activity; and protein homodimerization activity. Involved in chromosome condensation and negative regulation of transcription, DNA-templated. Located in nucleus and polytene chromosome. Part of NuRD complex. Is expressed in several structures, including gonad. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to several human genes including MBD3 (methyl-CpG binding domain protein 3). [provided by Alliance of Genome Resources, Apr 2022] |