ENSP00000249910 (Macaca fascicularis)
MBD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF01429 (MBD) IPR001739 ENSP00000249910 T261266_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000249910 MBD 77 151

Links

Other MBD family TFs
Other Macaca fascicularis TFs

37 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
MBD4 Macaca mulatta ENSMMUG00000012723 N 1.000
ENSPANG00000015047 Papio anubis ENSPANG00000015047 N 0.973
ENSCSAG00000009037 Chlorocebus sabaeus ENSCSAG00000009037 N 0.973
ENSNLEG00000005337 Nomascus leucogenys ENSNLEG00000005337 N 0.960
MBD4 Homo sapiens ENSG00000129071 N 0.947
ENSPPYG00000013417 Pongo abelii ENSPPYG00000013417 N 0.947
MBD4 Gorilla gorilla ENSGGOG00000010698 N 0.947
MBD4 Pan troglodytes ENSPTRG00000015377 N 0.947
MBD4 Callithrix jacchus ENSCJAG00000017293 N 0.920
MBD4 Vicugna pacos ENSVPAG00000004040 N 0.893
MBD4 Procavia capensis ENSPCAG00000012915 N 0.880
MBD4 Otolemur garnettii ENSOGAG00000010236 N 0.880
Myotis_brandtii_MBD4_10028283 Myotis brandtii Myotis_brandtii_MBD4_10028283 N 0.880
MBD4 Pteropus vampyrus ENSPVAG00000005238 N 0.867
MBD4 Microcebus murinus ENSMICG00000008022 N 0.867
MBD4 Loxodonta africana ENSLAFG00000010609 N 0.867
MBD4 Equus caballus ENSECAG00000022106 N 0.867
MBD4 Dasypus novemcinctus ENSDNOG00000049619 N 0.867
MBD4 Tursiops truncatus ENSTTRG00000011265 N 0.853
MBD4 Myotis lucifugus ENSMLUG00000014766 N 0.853
ENSSTOG00000020663 Ictidomys tridecemlineatus ENSSTOG00000020663 N 0.853
MBD4 Canis familiaris ENSCAFG00000004867 N 0.840
ENSMPUG00000017195 Mustela putorius furo ENSMPUG00000017195 N 0.840
ENSAMEG00000004562 Ailuropoda melanoleuca ENSAMEG00000004562 N 0.840
MBD4 Felis catus ENSFCAG00000000083 N 0.840
ENSTSYG00000011147 Tarsius syrichta ENSTSYG00000011147 N 0.827
Mbd4 Rattus norvegicus ENSRNOG00000010919 N 0.827
Mbd4 Mus musculus ENSMUSG00000030322 N 0.827
MBD4 Oryctolagus cuniculus ENSOCUG00000013006 N 0.813
MBD4 Erinaceus europaeus ENSEEUG00000011459 N 0.800
MBD4 Tupaia belangeri ENSTBEG00000003041 N 0.787
ENSCPOG00000004970 Cavia porcellus ENSCPOG00000004970 N 0.760
MBD4 Ochotona princeps ENSOPRG00000000473 N 0.747
MBD4 Bos taurus ENSBTAG00000021645 N 0.733
ENSOARG00000014699 Ovis aries ENSOARG00000014699 N 0.733
MBD4 Monodelphis domestica ENSMODG00000006399 N 0.732
ENSSHAG00000012953 Sarcophilus harrisii ENSSHAG00000012953 N 0.707