MYB11 (Arabidopsis thaliana)
Myb/SANT

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00249 (Myb_DNA-binding) IPR014778 AT3G62610 T266477_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
''MYB12 belongs to subgroup 7 of the R2R3-MYB family. It strongly activates the promoters of chalcone synthase (CHS), flavanone 3-hydroxylase (F3H), flavonol synthase (FLS) and - to a lesser extent - chalcone flavanone isomerase (CHI), but cannot activate the promoters of flavonoid-3'hydroxylase (F3'H) and dihydroflavonol 4-reductase (DF). The activation requires a functional MYB recognition element (MRE). Results from the myb12-1f allele indicate that an activation domain might be present in the C-terminus. Overexpression or knock-out plants do not show any obvious phenotype under greenhouse conditions. Young myb12-ko seedlings contain reduced amounts of flavonoids (quercetin and kaempferol), while seedlings as well as leaves of MYB12-OX plants displayed an increased flavonoid content. They did not show any significant difference in anthocyanin content. Expression of CHS and FLS shows a clear correlation to MYB12 expression levels. CHI and F3H show increased transcript levels in the MYB12-OX lines, but no differences in the knock-out. Even in the absence of functional MYB12, flavonol biosynthesis is not completely absent, suggesting functional redundancy. '' The redundant factors are MYB11 and MYB111 although MYB12 is primarily required for flavonol biosynthesis in roots. Mutations in MYB12 block both auxin and ethylene stimulation of flavonoid synthesis.

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
PK06182.1
M02349_2.00
Cannabis sativa
WTACCTACCN

NGGTAGGTAW
PBM
Weirauch et al.(2014)
pTH9581
0.751 0.849
MYB111
M00882_2.00
Arabidopsis thaliana
NNNAMCDAMY

RKTHGKTNNN
PBM
Franco-Zorrilla et al.(2014)
MYB111
0.679 0.817
For this family, TFs with SR scores > 0.661 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
AT3G62610.1 Myb 14 61
AT3G62610.1 Myb 67 112

Links

Other Myb/SANT family TFs
Other Arabidopsis thaliana TFs

125 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
Bostr.13158s0261 Boechera stricta Bostr.13158s0261 I 0.802
ATMYB11 Arabidopsis lyrata fgenesh1_pg.C_scaffold_5002710 I 0.797
Thhalv10006080m.g Eutrema salsugineum Thhalv10006080m.g I 0.797
Bo3g039690 Brassica oleracea Bo3g039690 I 0.777
Bostr.25993s0011 Boechera stricta Bostr.25993s0011 I 0.774
Thhalv10001498m.g Eutrema salsugineum Thhalv10001498m.g I 0.774
Cagra.13170s0007 Capsella grandiflora Cagra.13170s0007 I 0.772
Carubv10019345m.g Capsella rubella Carubv10019345m.g I 0.772
MYB12 Arabidopsis thaliana AT2G47460 I 0.770
MYB12 Arabidopsis lyrata fgenesh2_kg.4__2983__AT2G47460.1 I 0.770
Bra000453 Brassica rapa Bra000453 I 0.757
Gorai.001G143200 Gossypium raimondii Gorai.001G143200 I 0.754
Pavir.Ib01420 Panicum virgatum Pavir.Ib01420 I 0.752
LPERR03G12690 Leersia perrieri LPERR03G12690 I 0.752
Si039538m.g Setaria italica Si039538m.g I 0.752
PK06182.1 Cannabis sativa PK06182.1 D 0.751
GSMUA_Achr8G10470_001 Musa acuminata GSMUA_Achr8G10470_001 I 0.750
gene02324-v1.0-hybrid Fragaria vesca gene02324-v1.0-hybrid I 0.750
GRMZM2G051528 Zea mays GRMZM2G051528 I 0.743
Bo4g004500 Brassica oleracea Bo4g004500 I 0.741
Aquca_003_00583 Aquilegia coerulea Aquca_003_00583 I 0.739
BGIOSGA010900 Oryza indica BGIOSGA010900 I 0.735
GSMUA_AchrUn_randomG12700_001 Musa acuminata GSMUA_AchrUn_randomG12700_001 I 0.735
ORUFI03G15030 Oryza rufipogon ORUFI03G15030 I 0.735
OBART03G14380 Oryza barthii OBART03G14380 I 0.735
OMERI03G13130 Oryza meridionalis OMERI03G13130 I 0.735
ONIVA03G15280 Oryza nivara ONIVA03G15280 I 0.735
GRMZM2G022686 Zea mays GRMZM2G022686 I 0.735
Solyc01g079620.2 Solanum lycopersicum Solyc01g079620.2 I 0.734
PGSC0003DMG400009033 Solanum tuberosum PGSC0003DMG400009033 I 0.734
Cla017646 Citrullus lanatus Cla017646 I 0.733
Cucsa.069500 Cucumis sativus Cucsa.069500 I 0.732
Cla009418 Citrullus lanatus Cla009418 I 0.732
Traes_4AS_3883DC244 Triticum aestivum Traes_4AS_3883DC244 I 0.731
F775_11235 Aegilops tauschii F775_11235 I 0.731
MLOC_57220 Hordeum vulgare MLOC_57220 I 0.731
TRIUR3_31689 Triticum urartu TRIUR3_31689 I 0.731
Traes_4DL_967152326 Triticum aestivum Traes_4DL_967152326 I 0.731
Carubv10024801m.g Capsella rubella Carubv10024801m.g I 0.729
Sb01g037670 Sorghum bicolor Sb01g037670 I 0.729
OPUNC03G13890 Oryza punctata OPUNC03G13890 I 0.728
GRMZM2G057027 Zea mays GRMZM2G057027 I 0.728
GRMZM2G084799 Zea mays GRMZM2G084799 I 0.728
Traes_1DS_711044AD5 Triticum aestivum Traes_1DS_711044AD5 I 0.727
GSMUA_Achr5G21250_001 Musa acuminata GSMUA_Achr5G21250_001 I 0.723
GRMZM2G051256 Zea mays GRMZM2G051256 I 0.717
GLYMA17G03480 Glycine max GLYMA17G03480 I 0.716
MTR_4g121460 Medicago truncatula MTR_4g121460 I 0.716
BRADI1G64687 Brachypodium distachyon BRADI1G64687 I 0.715
TCM_004777 Theobroma cacao TCM_004777 I 0.712
Bra036145 Brassica rapa Bra036145 I 0.712
MTR_2g034790 Medicago truncatula MTR_2g034790 I 0.711
GLYMA09G04370 Glycine max GLYMA09G04370 I 0.709
PRUPE_ppa004560mg Prunus persica PRUPE_ppa004560mg I 0.709
MDP0000607330 Malus domestica MDP0000607330 I 0.709
GLYMA07G37142 Glycine max GLYMA07G37142 I 0.709
GLYMA15G15400 Glycine max GLYMA15G15400 I 0.709
MDP0000119725 Malus domestica MDP0000119725 I 0.709
Si002107m.g Setaria italica Si002107m.g I 0.708
Sb03g012550 Sorghum bicolor Sb03g012550 I 0.708
Ciclev10020307m.g Citrus clementina Ciclev10020307m.g I 0.704
orange1.1g014829m.g Citrus sinensis orange1.1g014829m.g I 0.704
OB03G24320 Oryza brachyantha OB03G24320 I 0.704
GLYMA10G01801 Glycine max GLYMA10G01801 I 0.703
SapurV1A.0180s0510 Salix purpurea SapurV1A.0180s0510 I 0.703
Lus10036336.g Linum usitatissimum Lus10036336.g I 0.703
Gorai.008G141000 Gossypium raimondii Gorai.008G141000 I 0.703
POPTR_0002s19920 Populus trichocarpa POPTR_0002s19920 I 0.703
SapurV1A.0158s0390 Salix purpurea SapurV1A.0158s0390 I 0.701
chr5.CM0239.580.nc Lotus japonicus chr5.CM0239.580.nc I 0.701
POPTR_0014s11780 Populus trichocarpa POPTR_0014s11780 I 0.700
Ciclev10005376m.g Citrus clementina Ciclev10005376m.g I 0.699
cassava40469.m1 Manihot esculenta cassava40469.m1 I 0.699
PK16958.1 Cannabis sativa PK16958.1 I 0.699
GLYMA02G01740 Glycine max GLYMA02G01740 I 0.699
orange1.1g041081m.g Citrus sinensis orange1.1g041081m.g I 0.699
BRADI2G11676 Brachypodium distachyon BRADI2G11676 I 0.698
cassava24756.valid.m1 Manihot esculenta cassava24756.valid.m1 I 0.695
VIT_07s0005g01210 Vitis vinifera VIT_07s0005g01210 I 0.695
Gorai.007G124000 Gossypium raimondii Gorai.007G124000 I 0.692
POPTR_0010s15090 Populus trichocarpa POPTR_0010s15090 I 0.692
Cucsa.252700 Cucumis sativus Cucsa.252700 I 0.688
gene05167-v1.0-hybrid Fragaria vesca gene05167-v1.0-hybrid I 0.688
Thhalv10004518m.g Eutrema salsugineum Thhalv10004518m.g I 0.688
OGLUM03G14490 Oryza glumaepatula OGLUM03G14490 I 0.687
F775_21522 Aegilops tauschii F775_21522 I 0.687
ORGLA03G0138900 Oryza glaberrima ORGLA03G0138900 I 0.687
Solyc06g009710.2 Solanum lycopersicum Solyc06g009710.2 I 0.687
TCM_021317 Theobroma cacao TCM_021317 I 0.687
Cla022107 Citrullus lanatus Cla022107 I 0.685
PRUPE_ppa007594mg Prunus persica PRUPE_ppa007594mg I 0.684
F775_18434 Aegilops tauschii F775_18434 I 0.681
SapurV1A.0050s0720 Salix purpurea SapurV1A.0050s0720 I 0.681
mgf003233m Mimulus guttatus mgf003233m I 0.681
Lus10002435.g Linum usitatissimum Lus10002435.g I 0.679
MYB111 Arabidopsis lyrata scaffold_801313.1 I 0.679
Bo7g092680 Brassica oleracea Bo7g092680 I 0.679
Bra037419 Brassica rapa Bra037419 I 0.679
Carubv10026694m.g Capsella rubella Carubv10026694m.g I 0.679
Cagra.6296s0007 Capsella grandiflora Cagra.6296s0007 I 0.679
MYB111 Arabidopsis thaliana AT5G49330 D 0.679
PGSC0003DMG400004371 Solanum tuberosum PGSC0003DMG400004371 I 0.678
PGSC0003DMG400007304 Solanum tuberosum PGSC0003DMG400007304 I 0.678
Solyc12g049350.1 Solanum lycopersicum Solyc12g049350.1 I 0.678
Gorai.011G195100 Gossypium raimondii Gorai.011G195100 I 0.677
evm.TU.supercontig_18.11 Carica papaya evm.TU.supercontig_18.11 I 0.677
OS01G0305900 Oryza sativa OS01G0305900 I 0.676
OGLUM01G14390 Oryza glumaepatula OGLUM01G14390 I 0.676
ORUFI01G13920 Oryza rufipogon ORUFI01G13920 I 0.676
BGIOSGA003345 Oryza indica BGIOSGA003345 I 0.676
GLYMA19G40250 Glycine max GLYMA19G40250 I 0.675
TRIUR3_05136 Triticum urartu TRIUR3_05136 I 0.674
GLYMA03G37640 Glycine max GLYMA03G37640 I 0.674
mgf012733m Mimulus guttatus mgf012733m I 0.673
Pm008294 Prunus mume Pm008294 I 0.672
Bostr.15774s0064 Boechera stricta Bostr.15774s0064 I 0.672
PDK_20s1388491g004 Phoenix dactylifera PDK_20s1388491g004 I 0.670
TCM_021318 Theobroma cacao TCM_021318 I 0.668
MTR_7g109320 Medicago truncatula MTR_7g109320 I 0.667
mgf024278m Mimulus guttatus mgf024278m I 0.667
OB01G22640 Oryza brachyantha OB01G22640 I 0.666
Ca_03498 Cicer arietinum Ca_03498 I 0.666
Lus10010273.g Linum usitatissimum Lus10010273.g I 0.666
Lus10001458.g Linum usitatissimum Lus10001458.g I 0.663
Eucgr.A00200 Eucalyptus grandis Eucgr.A00200 I 0.663