HHO5 (Arabidopsis thaliana)
Myb/SANT

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00249 (Myb_DNA-binding) IPR014778 AT4G37180 T266506_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Homeobox gene controlling the stem cell pool. Expressed in the stem cell organizing center of meristems. Required to keep the stem cells in an undifferentiated state. Regulation of WUS transcription is a central checkpoint in stem cell control. The size of the WUS expression domain controls the size of the stem cell population through WUS indirectly activating the expression of CLAVATA3 (CLV3) in the stem cells and CLV3 repressing WUS transcription through the CLV1 receptor kinase signaling pathway. Repression of WUS transcription through AGAMOUS (AG) activity controls stem cell activity in the determinate floral meristem. Binds to TAAT element core motif. WUS is also involved in cell differentiation during anther development.

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
HHO5
M07112_2.00		 Arabidopsis thaliana
HNDAAGATTCH
DGAATCTTHND		 Dap-seq
OMalley et al.(2016)
AT4G37180_col_a		 (Direct) (Direct)
HHO5
M07113_2.00		 Arabidopsis thaliana
NNDAAGATTCY
RGAATCTTHNN		 Dap-seq
OMalley et al.(2016)
AT4G37180_colamp_a		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
HHO3
M02289_2.00 		Arabidopsis thaliana
NWGATWCBNN
NNVGWATCWN		 PBM
Weirauch et al.(2014)
pTH7278 		0.714 0.830
HHO3
M07016_2.00 		Arabidopsis thaliana
NNDHNNAAKATTCY
RGAATMTTNNDHNN		 Dap-seq
OMalley et al.(2016)
At1g25550_colamp_a 		0.714 0.830
HHO3
M07017_2.00 		Arabidopsis thaliana
HNNAAKATTCY
RGAATMTTNND		 Dap-seq
OMalley et al.(2016)
At1g25550_col 		0.714 0.830
EFM
M07044_2.00 		Arabidopsis thaliana
NNGAATATTCY
RGAATATTCNN		 Dap-seq
OMalley et al.(2016)
At2g03500_col_a 		0.711 0.809
EFM
M07045_2.00 		Arabidopsis thaliana
RGAATCHWAGATTC
GAATCTWDGATTCY		 Dap-seq
OMalley et al.(2016)
At2g03500_colamp_a 		0.711 0.809
NIGT1
M02328_2.00 		Oryza sativa
NNKATHCNNN
NNNGDATMNN		 PBM
Weirauch et al.(2014)
pTH8646 		0.705 0.787
HRS1
M02284_2.00 		Arabidopsis thaliana
AGATTCYN
NRGAATCT		 PBM
Weirauch et al.(2014)
pTH7118 		0.703 0.787
HRS1
M01068_2.00 		Arabidopsis thaliana
NAGATTCBNN
NNVGAATCTN		 PBM
Sullivan et al.(2014)
pTH7648 		0.703 0.787
HRS1
M07004_2.00 		Arabidopsis thaliana
NDDWWVNAAKATTCY
RGAATMTTNBWWHHN		 Dap-seq
OMalley et al.(2016)
At1g13300_col_a 		0.703 0.787
HHO2
M02290_2.00 		Arabidopsis thaliana
NNKATHCNNN
NNNGDATMNN		 PBM
Weirauch et al.(2014)
pTH7115 		0.696 0.809
HHO2
M07029_2.00 		Arabidopsis thaliana
AKATTCY
RGAATMT		 Dap-seq
OMalley et al.(2016)
At1g68670_colamp_a 		0.696 0.809
HHO2
M07030_2.00 		Arabidopsis thaliana
RDATYNNAGATTC
GAATCTNNRATHY		 Dap-seq
OMalley et al.(2016)
At1g68670_col 		0.696 0.809
PK19779.1
M02354_2.00 		Cannabis sativa
NNKATNCNNN
NNNGNATMNN		 PBM
Weirauch et al.(2014)
pTH9610 		0.687 0.787
HHO6
M07024_2.00 		Arabidopsis thaliana
GAATCTNNDAT
ATHNNAGATTC		 Dap-seq
OMalley et al.(2016)
AT1G49560_col_a 		0.669 0.809
HHO6
M07025_2.00 		Arabidopsis thaliana
DGAATCTHNGATHCN
NGDATCNDAGATTCH		 Dap-seq
OMalley et al.(2016)
AT1G49560_colamp_a 		0.669 0.809
For this family, TFs with SR scores > 0.661 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
AT4G37180.1 Myb 212 263
AT4G37180.2 Myb 219 270
AT4G37180.3 Myb 212 262

Links

Other Myb/SANT family TFs
Other Arabidopsis thaliana TFs

Invalid Input OrderBy

341 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action