CDC5L (Homo sapiens)
Myb/SANT

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00249 (Myb_DNA-binding) IPR014778 ENSG00000096401 T269575_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
CDC5L
M11049_2.00		 Homo sapiens
GWKTTAAYRTAD
HTAYRTTAAMWC		 Transfac
Matys et al.(2006)
V$CDC5_01		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
CDC5
M02698_2.00 		Arabidopsis thaliana
NVCGCTGAGBN
NVCTCAGCGBN		 SELEX
Mathelier et al.(2014)
MA0579.1 		0.814 0.870
CDC5
M11037_2.00 		Arabidopsis thaliana
NVCGCTGAGBN
NVCTCAGCGBN		 Transfac
Matys et al.(2006)
P$CDC5_01 		0.814 0.870
For this family, TFs with SR scores > 0.661 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000360532 Myb 8 54
ENSP00000360532 Myb 60 104

Links

Other Myb/SANT family TFs
Other Homo sapiens TFs

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575 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action