Terf2 (Mus musculus)
Myb/SANT

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00249 (Myb_DNA-binding) IPR014778 ENSMUSG00000031921 T269787_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables double-stranded telomeric DNA binding activity and protein homodimerization activity. Involved in anterograde axonal transport; negative regulation of telomere maintenance via recombination; and telomeric loop formation. Acts upstream of or within in utero embryonic development; positive regulation of telomere maintenance; and protection from non-homologous end joining at telomere. Located in chromosome, telomeric region and male germ cell nucleus. Is expressed in cerebral cortex and cortical plate. Used to study xeroderma pigmentosum. Orthologous to human TERF2 (telomeric repeat binding factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Terf2
M02323_2.00		 Mus musculus
NAACCCTAV
BTAGGGTTN		 PBM
Weirauch et al.(2014)
pTH7805		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.661 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M02323_2.00 Myb 51 99

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000065586 Myb 423 471
ENSMUSP00000068948 Myb 488 536
ENSMUSP00000118759 Myb 487 535

Links

Other Myb/SANT family TFs
Other Mus musculus TFs

Invalid Input OrderBy

54 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action