myrf (Danio rerio)
Ndt80/PhoG

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF05224 (NDT80_PhoG) IPR007888 ENSDARG00000078676 T299754_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity and sequence-specific DNA binding activity. Predicted to be involved in central nervous system myelin maintenance; positive regulation of transcription, DNA-templated; and protein autoprocessing. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum membrane and nucleus. Used to study eye disease. Orthologous to human MYRF (myelin regulatory factor). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
myrf
M02384_2.00		 Danio rerio
TGGTACCR
YGGTACCA		 PBM
Weirauch et al.(2014)
pTH8654		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
MYRF
M02385_2.00 		Homo sapiens
TGGTACCA
TGGTACCA		 PBM
Weirauch et al.(2014)
pTH9310 		0.825 0.825
Myrf
M02386_2.00 		Mus musculus
NNGTRHSNNN
NNNSDYACNN		 PBM
Weirauch et al.(2014)
pTH8554 		0.825 0.825
For this family, TFs with SR scores > 0.700 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M02384_2.00 Ndt80/PhoG 51 198

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000104600 Ndt80/PhoG 322 469
ENSDARP00000127515 Ndt80/PhoG 322 469

Links

Other Ndt80/PhoG family TFs
Other Danio rerio TFs

Invalid Input OrderBy

65 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action