NCBI Gene Info:Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and ubiquitin protein ligase activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and protein autoubiquitination. Predicted to act upstream of or within negative regulation of MHC class II biosynthetic process. Predicted to be located in cytosol; nuclear lumen; and plasma membrane. Predicted to be active in nucleus. Orthologous to human NFX1 (nuclear transcription factor, X-box binding 1). [provided by Alliance of Genome Resources, Apr 2022] |