HNF4A (Homo sapiens)
Nuclear receptor

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00105 (zf-C4) IPR001628 ENSG00000101076 T303212_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
HNF4A
M03357_2.00
Homo sapiens
RWTGRACTTTGSACYB

VRGTSCAAAGTYCAWY
SELEX
Jolma et al.(2013)
HNF4A_1
(Direct) (Direct)
HNF4A
M03358_2.00
Homo sapiens
RRGGKCAAAGTCCRBN

NVYGGACTTTGMCCYY
SELEX
Jolma et al.(2013)
HNF4A_2
(Direct) (Direct)
HNF4A
M03359_2.00
Homo sapiens
NDTGGACTTTGDACYB

VRGTHCAAAGTCCAHN
SELEX
Jolma et al.(2013)
HNF4A_3
(Direct) (Direct)
HNF4A
M03360_2.00
Homo sapiens
RRGGTCAAAGKTCA

TGAMCTTTGACCYY
SELEX
Jolma et al.(2013)
HNF4A_4
(Direct) (Direct)
HNF4A
M03361_2.00
Homo sapiens
VRGGTCAAAGTCCANN

NNTGGACTTTGACCYB
SELEX
Jolma et al.(2013)
HNF4A_5
(Direct) (Direct)
HNF4A
M03362_2.00
Homo sapiens
RRGTYCAAAGKTCAH

DTGAMCTTTGRACYY
SELEX
Jolma et al.(2013)
HNF4A_6
(Direct) (Direct)
HNF4A
M05573_2.00
Homo sapiens
RRGGTCAAAGGTCRN

NYGACCTTTGACCYY
SELEX
Yin et al.(2017)
HNF4A_eDBD_HT-SELEX_1
(Direct) (Direct)
HNF4A
M05574_2.00
Homo sapiens
RRGGTCAAAGTCCAH

DTGGACTTTGACCYY
SELEX
Yin et al.(2017)
HNF4A_eDBD_HT-SELEX_2
(Direct) (Direct)
HNF4A
M05575_2.00
Homo sapiens
RRGTCCAAAGGTCRN

NYGACCTTTGGACYY
SELEX
Yin et al.(2017)
HNF4A_eDBD_HT-SELEX_3
(Direct) (Direct)
HNF4A
M05576_2.00
Homo sapiens
DTGGACTTTGGACYY

RRGTCCAAAGTCCAH
SELEX
Yin et al.(2017)
HNF4A_eDBD_HT-SELEX_4
(Direct) (Direct)
HNF4A
M05577_2.00
Homo sapiens
RRGGTCAAAGGTCRN

NYGACCTTTGACCYY
SELEX
Yin et al.(2017)
HNF4A_eDBD_Methyl-HT-SELEX_1
(Direct) (Direct)
HNF4A
M05578_2.00
Homo sapiens
RRGGTCAAAGTCCRN

NYGGACTTTGACCYY
SELEX
Yin et al.(2017)
HNF4A_eDBD_Methyl-HT-SELEX_2
(Direct) (Direct)
HNF4A
M05579_2.00
Homo sapiens
RRGTCCAAAGGTCRN

NYGACCTTTGGACYY
SELEX
Yin et al.(2017)
HNF4A_eDBD_Methyl-HT-SELEX_3
(Direct) (Direct)
HNF4A
M05580_2.00
Homo sapiens
DTGGACTTTGGACYY

RRGTCCAAAGTCCAH
SELEX
Yin et al.(2017)
HNF4A_eDBD_Methyl-HT-SELEX_4
(Direct) (Direct)
HNF4A
M08219_2.00
Homo sapiens
VRGDBCAAAGKYCAN

NTGRMCTTTGVHCYB
ChIP-seq
Contrino et al.(2012)
Mv81
(Direct) (Direct)
HNF4A
M08220_2.00
Homo sapiens
AGTCCA

TGGACT
ChIP-seq
Contrino et al.(2012)
Mv82
(Direct) (Direct)
HNF4A
M09268_2.00
Homo sapiens
VRGKNCAAAGTYCA

TGRACTTTGNMCYB
Misc
Kulakovskiy et al.(2013)
HNF4A_HUMAN.H11MO.0.A
(Direct) (Direct)
HNF4A
M09605_2.00
Homo sapiens
NNVRGDNCAAAGKYCA

TGRMCTTTGNHCYBNN
Misc
Heinz et al.(2010)
HepG2-HNF4a_GSE25021
(Direct) (Direct)
HNF4A
M11105_2.00
Homo sapiens
VRGGNCAAAGKYCRB

VYGRMCTTTGNCCYB
Transfac
Matys et al.(2006)
V$HNF4_01_B
(Direct) (Direct)
HNF4A
M11106_2.00
Homo sapiens
NNNRGDBYAAAGKBCANND

HNNTGVMCTTTRVHCYNNN
Transfac
Matys et al.(2006)
V$HNF4_01
(Direct) (Direct)
HNF4A
M11107_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$HNF4A_09
(Direct) (Direct)
HNF4A
M11108_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$HNF4A_10
(Direct) (Direct)
HNF4A
M11109_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$HNF4ALPHA_Q6
(Direct) (Direct)
HNF4A
M11110_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$HNF4A_Q3
(Direct) (Direct)
HNF4A
M11111_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$HNF4A_Q6_01
(Direct) (Direct)
HNF4A
M11112_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$HNF4_Q6_01
(Direct) (Direct)
HNF4A
M11113_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$HNF4_Q6_02
(Direct) (Direct)
HNF4A
M11114_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$HNF4_Q6_03
(Direct) (Direct)
HNF4A
M11115_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$HNF4_Q6_04
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Hnf4a
M00182_2.00
Mus musculus
NNRGKYMRNN

NNYKRMCYNN
PBM
Badis et al.(2009)
Hnf4a_2640
0.995 1.000
Hnf4a
M03426_2.00
Mus musculus
RRGGTCAAAGTCCANN

NNTGGACTTTGACCYY
SELEX
Jolma et al.(2013)
Hnf4a_1
0.995 1.000
Hnf4a
M09308_2.00
Mus musculus
NRGKBCAAAGTYCA

TGRACTTTGVMCYN
Misc
Kulakovskiy et al.(2013)
HNF4A_MOUSE.H11MO.0.A
0.995 1.000
HNF4G
M08155_2.00
Homo sapiens
NVRGDNCAAAGKYCA

TGRMCTTTGNHCYBN
ChIP-seq
Mathelier et al.(2014)
MA0484.1
0.994 0.929
HNF4G
M09287_2.00
Homo sapiens
VRGDNCAAAGKYCA

TGRMCTTTGNHCYB
Misc
Kulakovskiy et al.(2013)
HNF4G_HUMAN.H11MO.0.B
0.994 0.929
Hnf4g
M09307_2.00
Mus musculus
VRGDNCAAAGKYCA

TGRMCTTTGNHCYB
Misc
Kulakovskiy et al.(2013)
HNF4G_MOUSE.H11MO.0.C
0.994 0.929
HNF4G
M11155_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$HNF4G_01
0.994 0.929
HNF4G
M11156_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$HNF4G_02
0.994 0.929
Hnf4
M03935_2.00
Drosophila melanogaster
RGGKCAAAGGTCA

TGACCTTTGMCCY
SELEX
Nitta et al.(2015)
Hnf4_1
0.993 0.886
Hnf4
M03936_2.00
Drosophila melanogaster
RGGKCAAAGTYCA

TGRACTTTGMCCY
SELEX
Nitta et al.(2015)
Hnf4_2
0.993 0.886
Hnf4
M03937_2.00
Drosophila melanogaster
RGTVCAAAGKTCR

YGAMCTTTGBACY
SELEX
Nitta et al.(2015)
Hnf4_3
0.993 0.886
Hnf4
M03938_2.00
Drosophila melanogaster
RTGRACTTTGGACY

RGTCCAAAGTYCAY
SELEX
Nitta et al.(2015)
Hnf4_4
0.993 0.886
Hnf4
M06428_2.00
Drosophila melanogaster
DKNKWSSNGGGGTCA

TGACCCCNSSWMNMH
B1H
Zhu et al.(2011)
Hnf4_SANGER_10_FBgn0004914
0.993 0.886
Hnf4
M06429_2.00
Drosophila melanogaster
GGGGTCAH

DTGACCCC
B1H
Zhu et al.(2011)
Hnf4_SANGER_5_FBgn0004914
0.993 0.886
NR6A1
M05627_2.00
Homo sapiens
NNSAAGKTCAAGKKYRN

NYRMMCTTGAMCTTSNN
SELEX
Yin et al.(2017)
NR6A1_eDBD_HT-SELEX
0.844 0.529
NR6A1
M09284_2.00
Homo sapiens
AAGKTCAAGKTCA

TGAMCTTGAMCTT
Misc
Kulakovskiy et al.(2013)
NR6A1_HUMAN.H11MO.0.B
0.844 0.529
NR6A1
M11148_2.00
Homo sapiens
NKCAAGKTCAAGKTCANN

NNTGAMCTTGAMCTTGMN
Transfac
Matys et al.(2006)
V$GCNF_01
0.844 0.529
NR6A1
M11149_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$GCNF_Q3
0.844 0.529
NR6A1
M05628_2.00
Homo sapiens
NYSAAGKTCAAGKKCRN

NYGMMCTTGAMCTTSRN
SELEX
Yin et al.(2017)
NR6A1_eDBD_Methyl-HT-SELEX
0.844 0.529
nhr-49
M02413_2.00
Caenorhabditis elegans
NNNNWNHAN

NTDNWNNNN
PBM
Weirauch et al.(2014)
pTH5891
0.827 0.557
NR2F6
M02396_2.00
Homo sapiens
NNRGGTCR

YGACCYNN
PBM
Weirauch et al.(2014)
pTH6747
0.808 0.586
NR2F6
M03386_2.00
Homo sapiens
RRGGTCAAAAGGTCA

TGACCTTTTGACCYY
SELEX
Jolma et al.(2013)
NR2F6_1
0.808 0.586
NR2F6
M03387_2.00
Homo sapiens
RRGGTCAAAGGTCA

TGACCTTTGACCYY
SELEX
Jolma et al.(2013)
NR2F6_2
0.808 0.586
NR2F6
M03388_2.00
Homo sapiens
NRGGTCAAAGGTCA

TGACCTTTGACCYN
SELEX
Jolma et al.(2013)
NR2F6_3
0.808 0.586
NR2F6
M05641_2.00
Homo sapiens
RRGGTCAAAGGTCAN

NTGACCTTTGACCYY
SELEX
Yin et al.(2017)
NR2F6_eDBD_HT-SELEX_1
0.808 0.586
NR2F6
M05642_2.00
Homo sapiens
RAGGTCANTGACCTY

RAGGTCANTGACCTY
SELEX
Yin et al.(2017)
NR2F6_eDBD_HT-SELEX_2
0.808 0.586
NR2F6
M05645_2.00
Homo sapiens
NRGGTCARAGGTCRN

NYGACCTYTGACCYN
SELEX
Yin et al.(2017)
NR2F6_FL_HT-SELEX_1
0.808 0.586
NR2F6
M05646_2.00
Homo sapiens
NRGGTCANYGACCYY

RRGGTCRNTGACCYN
SELEX
Yin et al.(2017)
NR2F6_FL_HT-SELEX_2
0.808 0.586
NR2F6
M11153_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$EAR2_Q2
0.808 0.586
NR2F6
M11154_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$EAR2_Q4
0.808 0.586
NR2F6
M05643_2.00
Homo sapiens
RRGGTCAAAGGTCRN

NYGACCTTTGACCYY
SELEX
Yin et al.(2017)
NR2F6_eDBD_Methyl-HT-SELEX_1
0.808 0.586
NR2F6
M05644_2.00
Homo sapiens
RRGGTCRNYGACCYY

RRGGTCRNYGACCYY
SELEX
Yin et al.(2017)
NR2F6_eDBD_Methyl-HT-SELEX_2
0.808 0.586
NR2F6
M05647_2.00
Homo sapiens
NRGGTYADRGGKBRN

NYVMCCYHTRACCYN
SELEX
Yin et al.(2017)
NR2F6_FL_Methyl-HT-SELEX_1
0.808 0.586
NR2F6
M05648_2.00
Homo sapiens
NRGGTCANYGACCYN

NRGGTCRNTGACCYN
SELEX
Yin et al.(2017)
NR2F6_FL_Methyl-HT-SELEX_2
0.808 0.586
nr2f2
M02393_2.00
Danio rerio
NNRGGTCAN

NTGACCYNN
PBM
Weirauch et al.(2014)
pTH5882
0.801 0.557
Nr2f2
M00184_2.00
Mus musculus
RRGGTCAN

NTGACCYY
PBM
Badis et al.(2009)
Nr2f2_2192
0.801 0.557
Nr2f1
M00822_2.00
Mus musculus
DRGGTCRN

NYGACCYH
PBM
Weirauch et al.(2013)
pTH3811
0.801 0.557
NR2F1
M03403_2.00
Homo sapiens
RRGGTCAAAGGTCAN

NTGACCTTTGACCYY
SELEX
Jolma et al.(2013)
NR2F1_1
0.801 0.557
NR2F1
M03404_2.00
Homo sapiens
RRGGTCAARAGGTCAN

NTGACCTYTTGACCYY
SELEX
Jolma et al.(2013)
NR2F1_2
0.801 0.557
NR2F1
M03405_2.00
Homo sapiens
RRGGTCAN

NTGACCYY
SELEX
Jolma et al.(2013)
NR2F1_3
0.801 0.557
NR2F1
M03406_2.00
Homo sapiens
NHRRGGTCANVNG

CNBNTGACCYYDN
SELEX
Jolma et al.(2013)
NR2F1_4
0.801 0.557
NR2F1
M05661_2.00
Homo sapiens
NRGGTCAAAGGTCRN

NYGACCTTTGACCYN
SELEX
Yin et al.(2017)
NR2F1_eDBD_HT-SELEX_1
0.801 0.557
NR2F1
M05662_2.00
Homo sapiens
VRGGTCANYGACCYY

RRGGTCRNTGACCYB
SELEX
Yin et al.(2017)
NR2F1_eDBD_HT-SELEX_2
0.801 0.557
NR2F1
M05665_2.00
Homo sapiens
VRGGTCAAAGGTCAN

NTGACCTTTGACCYB
SELEX
Yin et al.(2017)
NR2F1_FL_HT-SELEX_1
0.801 0.557
NR2F1
M05666_2.00
Homo sapiens
RRGGTCANYGACCYY

RRGGTCRNTGACCYY
SELEX
Yin et al.(2017)
NR2F1_FL_HT-SELEX_2
0.801 0.557
NR2F2
M08157_2.00
Homo sapiens
NNAAGGTCANN

NNTGACCTTNN
ChIP-seq
Mathelier et al.(2014)
MA1111.1
0.801 0.557
NR2F2
M08223_2.00
Homo sapiens
AAAGGTCA

TGACCTTT
ChIP-seq
Contrino et al.(2012)
Mv102
0.801 0.557
NR2F2
M08224_2.00
Homo sapiens
GGKCARAGGB

VCCTYTGMCC
ChIP-seq
Contrino et al.(2012)
Mv104
0.801 0.557
NR2F1
M09291_2.00
Homo sapiens
NRRRBSRRRGGKCANVN

NBNTGMCCYYYSVYYYN
Misc
Kulakovskiy et al.(2013)
COT1_HUMAN.H11MO.0.C
0.801 0.557
NR2F2
M09293_2.00
Homo sapiens
NARRGGTCADRDN

NHYHTGACCYYTN
Misc
Kulakovskiy et al.(2013)
COT2_HUMAN.H11MO.0.A
0.801 0.557
Nr2f1
M09334_2.00
Mus musculus
YARAGGTCA

TGACCTYTR
Misc
Kulakovskiy et al.(2013)
COT1_MOUSE.H11MO.0.B
0.801 0.557
Nr2f2
M09325_2.00
Mus musculus
NNHRAGGTCANVD

HBNTGACCTYDNN
Misc
Kulakovskiy et al.(2013)
COT2_MOUSE.H11MO.0.A
0.801 0.557
NR2F2
M11180_2.00
Homo sapiens
WRRKKTCAARGGYTCA

TGARCCYTTGAMMYYW
Transfac
Matys et al.(2006)
V$ARP1_01
0.801 0.557
NR2F1
M11172_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$COUPTF1_Q6_01
0.801 0.557
NR2F2
M11181_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$COUPTF2_Q6
0.801 0.557
NR2F1
M05663_2.00
Homo sapiens
NRGGTCAAAGGTCRN

NYGACCTTTGACCYN
SELEX
Yin et al.(2017)
NR2F1_eDBD_Methyl-HT-SELEX_1
0.801 0.557
NR2F1
M05664_2.00
Homo sapiens
NRGGTCANYGACCYH

DRGGTCRNTGACCYN
SELEX
Yin et al.(2017)
NR2F1_eDBD_Methyl-HT-SELEX_2
0.801 0.557
NR2F1
M05667_2.00
Homo sapiens
NRGGTCAAAGGTCRN

NYGACCTTTGACCYN
SELEX
Yin et al.(2017)
NR2F1_FL_Methyl-HT-SELEX_1
0.801 0.557
NR2F1
M05668_2.00
Homo sapiens
RRGGTCRNYGACCYY

RRGGTCRNYGACCYY
SELEX
Yin et al.(2017)
NR2F1_FL_Methyl-HT-SELEX_2
0.801 0.557
svp
M06423_2.00
Drosophila melanogaster
ARGGTCA

TGACCYK
B1H
Zhu et al.(2011)
svp_SANGER_5_FBgn0003651
0.793 0.586
NR2E1
M02394_2.00
Homo sapiens
NGAGGTCARN

NYTGACCTCN
PBM
Weirauch et al.(2014)
pTH6281
0.772 0.586
Nr2e1
M00814_2.00
Mus musculus
NNNGTYRNNN

NNNYRACNNN
PBM
Weirauch et al.(2013)
pTH2936
0.772 0.586
A1YGC6_PANPA
M02421_2.00
Pan paniscus
NNGTCANNN

NNNTGACNN
PBM
Weirauch et al.(2014)
pTH5561
0.772 0.586
NR2E1
M03364_2.00
Homo sapiens
WDAAGTCAA

TTGACTTHW
SELEX
Jolma et al.(2013)
NR2E1_1
0.772 0.586
NR2E1
M03365_2.00
Homo sapiens
RARTCAWDAAGTCA

TGACTTHWTGAYTY
SELEX
Jolma et al.(2013)
NR2E1_2
0.772 0.586
Nr2e1
M03427_2.00
Mus musculus
WDAAGTCAW

WTGACTTHW
SELEX
Jolma et al.(2013)
Nr2e1_1
0.772 0.586
Nr2e1
M03428_2.00
Mus musculus
RRGTCAWDAAGTCA

TGACTTHWTGACYY
SELEX
Jolma et al.(2013)
Nr2e1_2
0.772 0.586
NR2E1
M05585_2.00
Homo sapiens
NNAAGTCAN

NTGACTTNN
SELEX
Yin et al.(2017)
NR2E1_FL_HT-SELEX
0.772 0.586
NR2E1
M05586_2.00
Homo sapiens
NDAAGTCAN

NTGACTTHN
SELEX
Yin et al.(2017)
NR2E1_FL_Methyl-HT-SELEX
0.772 0.586
tll
M02408_2.00
Drosophila melanogaster
NRASGTCAANNN

NNNTTGACSTYN
PBM
Weirauch et al.(2014)
pTH5714
0.752 0.571
tll
M03932_2.00
Drosophila melanogaster
NRAGTCAAAAGTCA

TGACTTTTGACTYN
SELEX
Nitta et al.(2015)
tll_1
0.752 0.571
tll
M03933_2.00
Drosophila melanogaster
NRAGTCAADAAGTCA

TGACTTHTTGACTYN
SELEX
Nitta et al.(2015)
tll_2
0.752 0.571
tll
M06558_2.00
Drosophila melanogaster
WAAAGTCAAM

KTTGACTTTW
B1H
Mathelier et al.(2014)
MA0459.1
0.752 0.571
tll
M06424_2.00
Drosophila melanogaster
AAAGTYA

TRACTTT
B1H
Zhu et al.(2011)
tll_FlyReg_FBgn0003720
0.752 0.571
tll
M06425_2.00
Drosophila melanogaster
WAAAGTCAAM

KTTGACTTTW
B1H
Zhu et al.(2011)
tll_NAR_FBgn0003720
0.752 0.571
tll
M09688_2.00
Drosophila melanogaster
MAAAGTCAAH

DTTGACTTTK
Misc
Kulakovskiy et al.(2009)
tll
0.752 0.571
tll
M11190_2.00
Drosophila melanogaster Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
I$TLL_Q6
0.752 0.571
usp
M03934_2.00
Drosophila melanogaster
ARRGGTCAAAGGTCA

TGACCTTTGACCYYT
SELEX
Nitta et al.(2015)
usp_1
0.752 0.614
usp
M06426_2.00
Drosophila melanogaster
HRRGGTCAH

DTGACCYYD
B1H
Zhu et al.(2011)
usp_SANGER_5_FBgn0003964
0.752 0.614
usp
M02709_2.00
Drosophila melanogaster
GGGGTCACSN

NSGTGACCCC
SELEX
Mathelier et al.(2014)
MA0016.1
0.752 0.614
usp
M09689_2.00
Drosophila melanogaster
KRGGTCACG

CGTGACCYM
Misc
Kulakovskiy et al.(2009)
usp
0.752 0.614
usp
M11191_2.00
Drosophila melanogaster
GRGGTCAYS

SRTGACCYC
Transfac
Matys et al.(2006)
I$CF1_01
0.752 0.614
usp
M11192_2.00
Drosophila melanogaster
GGGGTCAYS

SRTGACCCC
Transfac
Matys et al.(2006)
I$CF1_02
0.752 0.614
Rxrg
M02400_2.00
Mus musculus
VRGGTCAN

NTGACCYB
PBM
Weirauch et al.(2014)
pTH2880
0.750 0.571
RXRG
M03375_2.00
Homo sapiens
RRGGTCAAAGGTCA

TGACCTTTGACCYY
SELEX
Jolma et al.(2013)
RXRG_1
0.750 0.571
RXRG
M03376_2.00
Homo sapiens
RRGGTCATGACCYY

RRGGTCATGACCYY
SELEX
Jolma et al.(2013)
RXRG_2
0.750 0.571
RXRG
M03377_2.00
Homo sapiens
GRGGTCAAAGGTCA

TGACCTTTGACCYC
SELEX
Jolma et al.(2013)
RXRG_3
0.750 0.571
RXRG
M03378_2.00
Homo sapiens
NRGGTCATGACCYC

GRGGTCATGACCYN
SELEX
Jolma et al.(2013)
RXRG_4
0.750 0.571
RXRG
M02746_2.00
Homo sapiens
GGTCAAAGGTCA

TGACCTTTGACC
SELEX
Jolma et al.(2010)
RXRG_dimer
0.750 0.571
RXRG
M05615_2.00
Homo sapiens
VRGGTCAAAGGTCAN

NTGACCTTTGACCYB
SELEX
Yin et al.(2017)
RXRG_FL_HT-SELEX_1
0.750 0.571
RXRG
M05616_2.00
Homo sapiens
RRGGTCAYGACCYY

RRGGTCRTGACCYY
SELEX
Yin et al.(2017)
RXRG_FL_HT-SELEX_2
0.750 0.571
RXRG
M05879_2.00
Homo sapiens
RGGTBAARGGTBRND

HNYVACCYTTVACCY
SMiLE-seq
Isakova et al.(2017)
RXRg
0.750 0.571
RXRG
M09280_2.00
Homo sapiens
NGTCAAAGGTCAH

DTGACCTTTGACN
Misc
Kulakovskiy et al.(2013)
RXRG_HUMAN.H11MO.0.B
0.750 0.571
Rxrg
M09305_2.00
Mus musculus
VDDVDNSVNRAGKTCAAGGYCA

TGRCCTTGAMCTYNBSNHBHHB
Misc
Kulakovskiy et al.(2013)
RXRG_MOUSE.H11MO.0.B
0.750 0.571
RXRG
M05617_2.00
Homo sapiens
DRGGTBAARGGTBRN

NYVACCYTTVACCYH
SELEX
Yin et al.(2017)
RXRG_FL_Methyl-HT-SELEX_1
0.750 0.571
RXRG
M05618_2.00
Homo sapiens
VRGGTCAYGACCYB

VRGGTCRTGACCYB
SELEX
Yin et al.(2017)
RXRG_FL_Methyl-HT-SELEX_2
0.750 0.571
Rxrb
M02402_2.00
Mus musculus
VRGGTCAH

DTGACCYB
PBM
Weirauch et al.(2014)
pTH2861
0.748 0.614
RXRB
M03415_2.00
Homo sapiens
RRGGTCAAAGGTCA

TGACCTTTGACCYY
SELEX
Jolma et al.(2013)
RXRB_1
0.748 0.614
Rxrb
M03435_2.00
Mus musculus
GRGGTCAAAGGTCA

TGACCTTTGACCYC
SELEX
Jolma et al.(2013)
Rxrb_1
0.748 0.614
RXRB
M05681_2.00
Homo sapiens
RRGGTCAAAGGTCAN

NTGACCTTTGACCYY
SELEX
Yin et al.(2017)
RXRB_eDBD_HT-SELEX_1
0.748 0.614
RXRB
M05682_2.00
Homo sapiens
RRGGTCAYGACCYY

RRGGTCRTGACCYY
SELEX
Yin et al.(2017)
RXRB_eDBD_HT-SELEX_2
0.748 0.614
RXRB
M09297_2.00
Homo sapiens
DSAGGTCASD

HSTGACCTSH
Misc
Kulakovskiy et al.(2013)
RXRB_HUMAN.H11MO.0.C
0.748 0.614
Rxrb
M09330_2.00
Mus musculus
DSAGGTCASD

HSTGACCTSH
Misc
Kulakovskiy et al.(2013)
RXRB_MOUSE.H11MO.0.C
0.748 0.614
RXRB
M05683_2.00
Homo sapiens
RRGGTCAAAGGTCRN

NYGACCTTTGACCYY
SELEX
Yin et al.(2017)
RXRB_eDBD_Methyl-HT-SELEX_1
0.748 0.614
RXRB
M05684_2.00
Homo sapiens
RRGGTCRYGACCYY

RRGGTCRYGACCYY
SELEX
Yin et al.(2017)
RXRB_eDBD_Methyl-HT-SELEX_2
0.748 0.614
Smp_105090
M02412_2.00
Schistosoma mansoni
RGGTCANN

NNTGACCY
PBM
Weirauch et al.(2014)
pTH6174
0.748 0.529
For this family, TFs with SR scores > 0.745 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000312987 Nuclear receptor 58 127
ENSP00000315180 Nuclear receptor 36 105
ENSP00000396216 Nuclear receptor 36 105
ENSP00000410911 Nuclear receptor 58 127
ENSP00000412111 Nuclear receptor 58 127
ENSP00000476310 Nuclear receptor 33 102
ENSP00000476609 Nuclear receptor 36 105
ENSP00000481331 Nuclear receptor 33 102

Links

Other Nuclear receptor family TFs
Other Homo sapiens TFs

1090 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
Alligator_sinensis_CCG013447.1 Alligator sinensis Alligator_sinensis_CCG013447.1 I 0.000
B39674 Xenopus laevis B39674 I 0.000
ENSAMEG00000015606 Ailuropoda melanoleuca ENSAMEG00000015606 I 0.000
USF1 Bos taurus ENSBTAG00000017873 I 0.000
USF1 Canis familiaris ENSCAFG00000012689 I 0.000
USF1 Choloepus hoffmanni ENSCHOG00000011010 I 0.000
USF1 Callithrix jacchus ENSCJAG00000005396 I 0.000
USF1 Cavia porcellus ENSCPOG00000003957 I 0.000
ENSCSAG00000002622 Chlorocebus sabaeus ENSCSAG00000002622 I 0.000
ARHGAP30 Dasypus novemcinctus ENSDNOG00000005811 I 0.000
USF1 Equus caballus ENSECAG00000004755 I 0.000
USF1 Felis catus ENSFCAG00000012307 I 0.000
USF1 Homo sapiens ENSG00000158773 D 0.000
USF1 Gorilla gorilla ENSGGOG00000003935 I 0.000
ENSLACG00000001157 Latimeria chalumnae ENSLACG00000001157 I 0.000
USF1 Loxodonta africana ENSLAFG00000011338 I 0.000
ENSLOCG00000000641 Lepisosteus oculatus ENSLOCG00000000641 I 0.000
ENSMEUG00000009683 Macropus eugenii ENSMEUG00000009683 I 0.000
USF1 Microcebus murinus ENSMICG00000007199 I 0.000
USF1 Myotis lucifugus ENSMLUG00000009179 I 0.000
USF1 Macaca mulatta ENSMMUG00000002003 I 0.000
ENSMMUP00000002682 Macaca fascicularis ENSMMUP00000002682 I 0.000
USF1 Monodelphis domestica ENSMODG00000005443 I 0.000
ENSMPUG00000014181 Mustela putorius furo ENSMPUG00000014181 I 0.000
Usf1 Mus musculus ENSMUSG00000026641 D 0.000
ENSNLEG00000013935 Nomascus leucogenys ENSNLEG00000013935 I 0.000
ENSOARG00000009376 Ovis aries ENSOARG00000009376 I 0.000
USF1 Oryctolagus cuniculus ENSOCUG00000002352 I 0.000
ENSOGAG00000006705 Otolemur garnettii ENSOGAG00000006705 I 0.000
ENSONIG00000016360 Oreochromis niloticus ENSONIG00000016360 I 0.000
USF1 Ochotona princeps ENSOPRG00000003858 I 0.000
ENSP00000357000-D1 Bos grunniens ENSP00000357000-D1 I 0.000
ENSPANG00000016141 Papio anubis ENSPANG00000016141 I 0.000
ENSPPYG00000000619 Pongo abelii ENSPPYG00000000619 I 0.000
ENSPSIG00000008116 Pelodiscus sinensis ENSPSIG00000008116 I 0.000
USF1 Pan troglodytes ENSPTRG00000001565 I 0.000
USF1 Pteropus vampyrus ENSPVAG00000005489 I 0.000
Usf1 Rattus norvegicus ENSRNOG00000004255 I 0.000
ENSSHAG00000016124 Sarcophilus harrisii ENSSHAG00000016124 I 0.000
USF1 Sus scrofa ENSSSCG00000006371 I 0.000
ENSSTOG00000012364 Ictidomys tridecemlineatus ENSSTOG00000012364 I 0.000
USF1 Tupaia belangeri ENSTBEG00000003164 I 0.000
USF1 Tursiops truncatus ENSTTRG00000009151 I 0.000
USF1 Vicugna pacos ENSVPAG00000008421 I 0.000
Ogr08237 Ophisaurus gracilis Ogr08237 I 0.000
PHUM287950 Pediculus humanus PHUM287950 I 0.000
Pvit_07548 Pogona vitticeps Pvit_07548 I 0.000
usf1 Xenopus tropicalis XB-GENE-5918718 I 0.000
usf1.S Xenopus laevis XB-GENE-6255904 I 0.000