nhr-46 (Caenorhabditis elegans)
Nuclear receptor

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00105 (zf-C4) IPR001628 WBGene00003636 T306160_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in hypodermis; intestine; muscle cell; neurons; and reproductive system. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
nhr-46
M00692_2.00		 Caenorhabditis elegans
NNNDWNHRN
NYDNWHNNN		 PBM
Narasimhan et al.(2015)
pTH9924		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.745 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00692_2.00 Nuclear receptor 51 121

DNA Binding Domains

Protein ID Domain From To Sequence
C45E5.6a.1 Nuclear receptor 96 166
C45E5.6a.2 Nuclear receptor 96 166
C45E5.6b Nuclear receptor 144 214
C45E5.6c.1 Nuclear receptor 1 33
C45E5.6c.2 Nuclear receptor 1 33
C45E5.6c.3 Nuclear receptor 1 33
C45E5.6c.4 Nuclear receptor 1 33
C45E5.6c.5 Nuclear receptor 1 33
C45E5.6c.6 Nuclear receptor 1 33
C45E5.6d.1 Nuclear receptor 99 169
C45E5.6d.2 Nuclear receptor 99 169

Links

Other Nuclear receptor family TFs
Other Caenorhabditis elegans TFs

20 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CRE30546 Caenorhabditis remanei CRE30546 I 0.992
CRE28659 Caenorhabditis remanei CRE28659 I 0.992
CJA19491 Caenorhabditis japonica CJA19491 I 0.992
CBN08077 Caenorhabditis brenneri CBN08077 I 0.991
CBN16259 Caenorhabditis brenneri CBN16259 I 0.991
CBG19870 Caenorhabditis briggsae CBG19870 I 0.991
ANCCAN_22589 Ancylostoma caninum ANCCAN_22589 I 0.932
scaffold303-EXSNAP2012.4 Pristionchus exspectatus scaffold303-EXSNAP2012.4 I 0.928
L893_g13425 Steinernema glaseri L893_g13425 I 0.922
L892_g3686 Steinernema scapterisci L892_g3686 I 0.918
L898_g30036 Steinernema monticolum L898_g30036 I 0.918
L889_g304 Steinernema feltiae L889_g304 I 0.918
L596_g14937 Steinernema carpocapsae L596_g14937 I 0.918
PPA17263 Pristionchus pacificus PPA17263 I 0.916
scaffold731-EXSNAP2012.1 Pristionchus exspectatus scaffold731-EXSNAP2012.1 I 0.916
scaffold19-EXSNAP2012.26 Pristionchus exspectatus scaffold19-EXSNAP2012.26 I 0.898
nhr-118 Caenorhabditis elegans WBGene00003708 I 0.777
Minc11986 Meloidogyne incognita Minc11986 I 0.755
augustus_masked-nMf.1.1.scaf00383-processed-gene-0.1 Meloidogyne floridensis augustus_masked-nMf.1.1.scaf00383-processed-gene-0.1 I 0.755