CIS-BP Database: Catalog of Inferred Sequence Binding Preferences - Update
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nhr-130
(
Caenorhabditis elegans
)
Nuclear receptor
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00105 (zf-C4)
IPR001628
WBGene00003720
T306242_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease; hepatocellular carcinoma; lipid metabolism disorder; and myocardial infarction. Orthologous to human PPARA (peroxisome proliferator activated receptor alpha). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
nhr-182
M00701_2.00
Caenorhabditis elegans
DWBYGTGWCH
DGWCACRVWH
PBM
Narasimhan et al.(2015)
pTH10779
0.931
0.571
nhr-182
M00702_2.00
Caenorhabditis elegans
NNNHRTRNHN
NDNYAYDNNN
PBM
Narasimhan et al.(2015)
pTH6106
0.931
0.571
CBG01250
M02391_2.00
Caenorhabditis briggsae
WBYGTGTC
GACACRVW
PBM
Weirauch et al.(2014)
pTH6110
0.855
0.529
nhr-232
M00700_2.00
Caenorhabditis elegans
NNTNTDWYN
NRWHANANN
PBM
Narasimhan et al.(2015)
pTH10647
0.816
0.486
nhr-84
M02414_2.00
Caenorhabditis elegans
NRGTCACAAN
NTTGTGACYN
PBM
Weirauch et al.(2014)
pTH5828
0.746
0.571
For this family, TFs with SR scores >
0.745
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
T01G6.8
Nuclear receptor
35
105
YTCQVCALPAHGNHFGAISCRACAAFFRRACTGTKTTYKCKKQNNCDIWENGRYKCKKCRLDRCNEVGMDP
Links
Other
Nuclear receptor
family TFs
Other
Caenorhabditis elegans
TFs
69 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy