nhr-209 (Caenorhabditis elegans)
Nuclear receptor

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00105 (zf-C4) IPR001628 WBGene00011100 T306285_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in anatomical structure development; cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in Fanconi renotubular syndrome 4; familial combined hyperlipidemia; hypoglycemia; maturity-onset diabetes of the young type 1; and type 2 diabetes mellitus. Orthologous to human HNF4A (hepatocyte nuclear factor 4 alpha) and HNF4G (hepatocyte nuclear factor 4 gamma). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
nhr-154
M00698_2.00 		Caenorhabditis elegans
NRBRYCAHWD
HWDTGRYVYN		 PBM
Narasimhan et al.(2015)
pTH10650 		0.815 0.586
CBG23380
M01296_2.00 		Caenorhabditis briggsae
NDBDHHANWN
NWNTDDHVHN		 PBM
Lambert et al.(2019)
pTH11449 		0.807 0.571
For this family, TFs with SR scores > 0.745 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
R07B7.16 Nuclear receptor 44 116

Links

Other Nuclear receptor family TFs
Other Caenorhabditis elegans TFs

7 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CBG23379 Caenorhabditis briggsae CBG23379 I 0.934
nhr-154 Caenorhabditis elegans WBGene00007547 D 0.815
CRE27050 Caenorhabditis remanei CRE27050 I 0.807
CBN28497 Caenorhabditis brenneri CBN28497 I 0.807
CBG23380 Caenorhabditis briggsae CBG23380 D 0.807
CJA03696 Caenorhabditis japonica CJA03696 I 0.751
nhr-153 Caenorhabditis elegans WBGene00007546 I 0.751