nhr-139 (Caenorhabditis elegans)
Nuclear receptor

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00105 (zf-C4) IPR001628 WBGene00016365 T306326_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease; hepatocellular carcinoma; lipid metabolism disorder; and myocardial infarction. Orthologous to human PPARA (peroxisome proliferator activated receptor alpha). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
C33G8.8 Nuclear receptor 1 67

Links

Other Nuclear receptor family TFs
Other Caenorhabditis elegans TFs

19 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CRE27296 Caenorhabditis remanei CRE27296 N 0.955
CBN09901 Caenorhabditis brenneri CBN09901 N 0.949
nhr-162 Caenorhabditis elegans WBGene00016367 N 0.914
CRE08638 Caenorhabditis remanei CRE08638 N 0.911
nhr-271 Caenorhabditis elegans WBGene00011396 N 0.884
CBG17072 Caenorhabditis briggsae CBG17072 N 0.866
CRE08644 Caenorhabditis remanei CRE08644 N 0.856
CRE09074 Caenorhabditis remanei CRE09074 N 0.837
CBN21921 Caenorhabditis brenneri CBN21921 N 0.827
CRE08643 Caenorhabditis remanei CRE08643 N 0.820
CRE08641 Caenorhabditis remanei CRE08641 N 0.818
CRE08639 Caenorhabditis remanei CRE08639 N 0.811
nhr-63 Caenorhabditis elegans WBGene00003653 N 0.811
nhr-163 Caenorhabditis elegans WBGene00016368 N 0.805
nhr-107 Caenorhabditis elegans WBGene00003697 N 0.795
nhr-50 Caenorhabditis elegans WBGene00003640 N 0.782
nhr-140 Caenorhabditis elegans WBGene00016366 N 0.780
nhr-112 Caenorhabditis elegans WBGene00003702 N 0.779
CRE09075 Caenorhabditis remanei CRE09075 N 0.756